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Brain Metabolism clinical trials

View clinical trials related to Brain Metabolism.

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NCT ID: NCT03849963 Enrolling by invitation - Brain Metabolism Clinical Trials

Imaging Oxidative Metabolism and Neurotransmitter Synthesis in the Human Brain

HP Brain
Start date: July 30, 2020
Phase:
Study type: Observational

Investigators propose to develop hyperpolarized [13C]-labeled pyruvate as potential imaging probes to assess two essential in vivo processes in cerebral metabolism: oxidative metabolism and synthesis of a neurotransmitter in this observational study.

NCT ID: NCT03473678 Completed - Blood Pressure Clinical Trials

Dietary Nitrate and Healthy Older Adults

Start date: February 12, 2014
Phase: N/A
Study type: Interventional

This study investigates the influence of dietary nitrate supplementation on cardiovascular health and physical and cognitive performance in older adults. Participants will receive both a nitrate containing beetroot juice for 10 days and a nitrate depleted beetroot juice for 10 days

NCT ID: NCT02357550 Completed - Brain Metabolism Clinical Trials

Ketones Influence on Glucose Metabolism in Brain. A Human Positron Emission Tomography (PET) Study

Start date: March 2015
Phase: N/A
Study type: Interventional

This project tend to investigate the affection of ketone bodies on brain metabolism. This will be done by measuring human cerebral uptake of energy substrates, together with functional parameters, using PET imaging and appropriate radiotracers under hyperketonemia in healthy subjects by ketone infusion. Hypotheses 1. Increased levels of ketone bodies in healthy subjects leads to decreased glucose uptake by brain cells contributing to hyperglycaemia. 2. Increased levels of ketone bodies in healthy subjects leads to increased cerebral blood flow. 3. Altered oxygen consumption during hyperketonemia in healthy subjects.

NCT ID: NCT01562808 Completed - Cognition Clinical Trials

Change in Brain Metabolism and Cognitive Function by Aripiprazole

Start date: January 2009
Phase: N/A
Study type: Interventional

Dopamine receptor occupancy and brain metabolism were measured using positron emission tomography after the administration of aripiprazole. Working memory performance was also measured using N-back task. The investigators explored the relationship between changes in brain metabolism and working memory performance.