Clinical Trials Logo

Bipolar Disorder clinical trials

View clinical trials related to Bipolar Disorder.

Filter by:

NCT ID: NCT02804334 Terminated - Bipolar Disorder Clinical Trials

The Role of Molecules in Blood Cells for Diagnosing Bipolar Disorders

Start date: June 2016
Phase:
Study type: Observational

The goal of this project is to study ~45 molecules in blood cells that may differentiate patients with bipolar disorder from healthy controls.

NCT ID: NCT02757521 Terminated - Bipolar Disorder Clinical Trials

Nitrous TRD Bipolar Depression

Start date: March 25, 2016
Phase: Early Phase 1
Study type: Interventional

Investigators will study approximately 64 patients with Treatment-Resistant Bipolar Depressive Disorder, defined as a failure of at least 1 antidepressants in the current depressive episode and 2 lifetime medication failures. The study will last approximately 6 to 8 weeks, involving randomization into one of two treatment groups receiving 3 one hour long inhalation treatments over a week.

NCT ID: NCT02749006 Terminated - Bipolar Depression Clinical Trials

Efficacy of rTMS in Bipolar Depression

rTMS-BD
Start date: April 2016
Phase: N/A
Study type: Interventional

Bipolar Disorder is a common condition that is characterized by periods of mood elevation however periods of chronic and recurring depressive episodes are more common and can be severely disabling. Effective treatments exist, however a significant portion of bipolar depressed patients do not respond to, or have difficulty tolerating many of these interventions. Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulatory technique that is effective in major depression and there is evidence for its efficacy in bipolar depression which needs to be assessed in larger randomized controlled trials. This study is a randomised, double-blind, sham-controlled trial over four weeks. The primary objective is to assess improvement in depressive symptoms in acute bipolar depressed patients on treatment with intermittent Theta-Burst Stimulation (iTBS) in comparison to sham-rTMS.

NCT ID: NCT02740244 Terminated - Bipolar Depression Clinical Trials

Effect of Intermittent ThetaBurst Stimulation in Treatment-resistant Bipolar Depression

iTBS-BIP
Start date: January 2011
Phase: N/A
Study type: Interventional

The aim is to evaluate the evaluate the clinical interest and the safety of repetitive transcranial magnetic stimulation (rTMS) delivered as intermittent Theta burst stimulation(iTBS) on severity of depression in patients with treatment-resistant bipolar disorder.

NCT ID: NCT02727127 Terminated - Healthy Clinical Trials

Brain Ion Homeostasis, Lithium and Bipolar Disorder

Start date: September 2015
Phase:
Study type: Observational

In this project, investigators intend to carry out the first simultaneous, in vivo, imaging study of lithium content and sodium ion homeostasis in the brain of Bipolar Disorder (BPD) patients under Lithium therapy.

NCT ID: NCT02726659 Terminated - Bipolar Disorder Clinical Trials

Adjunctive Use of Celecoxib in the Treatment of Bipolar Postpartum Depression

Start date: May 2016
Phase: Phase 3
Study type: Interventional

The investigators will conduct a 6-week, randomized, double-blind, placebo-controlled trial of celecoxib as an add-on treatment to the mood stabilizer among women with bipolar I or II postpartum depression. Women who are taking a mood stabilizer for treatment of bipolar disorder in the postpartum treatment will receive either a placebo or celecoxib add-on treatment. Patients will be monitored regularly to assess psychiatric symptoms and side effects. The investigators aim to evaluate the potential antidepressant effect of celecoxib in bipolar postpartum depression.

NCT ID: NCT02707276 Terminated - Clinical trials for Bipolar Depression Depressed Phase

LFMS: Initial Trial in Geriatric Bipolar Depression

LFMS
Start date: September 7, 2016
Phase: N/A
Study type: Interventional

The primary aim of this study is to assess the efficacy of Low Field Magnetic Stimulation (LFMS) in treating symptoms of depression and anxiety in older adults suffering from bipolar depression. The investigators also aim to assess any cognitive benefits from regular LFMS treatments in older adults suffering from bipolar depression.

NCT ID: NCT02623504 Terminated - Bipolar Disorder Clinical Trials

DB/Maintenance of Equetro (Carbamazepine) in Children With Acute Manic or Mixed Bipolar 1 Disorder

Start date: October 24, 2016
Phase: Phase 4
Study type: Interventional

A phase 4 unequal randomization, double blind study to evaluate the dose tolerance and safety of extended release Equetro (carbamazepine) versus placebo followed by an Open label and long term maintenance treatment in children and adolescents aged 10-17 years diagnosed with acute manic or mixed Bipolar I Disorder

NCT ID: NCT02505022 Terminated - Schizophrenia Clinical Trials

Role Functioning Changes NOS

Start date: January 2016
Phase:
Study type: Observational

During this study the investigators will 1) collect measures of social cognition and social functioning in adolescents and young adults who are experiencing early symptoms of a major mental disorder; and 2) evaluate the predictive value and utility of a new role functioning assessment measure for individuals experiencing changes in their lives after an index episode of mental illness. This will happen in the context of providing treatment-as-usual to individuals who arrive seeking help with the early phases of mental illness.

NCT ID: NCT02472483 Terminated - Bipolar Disorder Clinical Trials

Effectiveness of TCC Followed by MBCT and Predictive Factors (Genetic, Clinical and Cognitive) Response

TCC-MBCT
Start date: September 13, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether a Cognitive and Behavioral group Therapy (CBT) + Mindfulness Based Cognitive Therapy (MBCT) decreased relapses and hospitalizations and improved outcomes (depressive and manic symptoms, self-esteem, and quality of life) in a large sample of refractory bipolar I patients on mood stabilizers.