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Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism — ENIGMA-I  

Autism Spectrum Disorder Clinical Trial

Official title:
Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism

Clinical Trial Summary

The aim of the study is to enrich the understanding of the physiological mechanisms that predispose autistic adolescents to mental illness. It will inform a possible pathway and biomarker handprint of mental illness severity and prognosis to formulate a neurobiologically informed personalization strategy that could be applied for selecting appropriate Evidence Based Intervention (EBI) for treating an adolescent formally diagnosed with Autism.

Clinical Trial Description

The goal of this observational study is: 1. to identify environmental factors which may significantly contribute to the already vulnerable mental health of autistic adolescents in the age group of 11 - 15 years in developing mental illness; 2. to perform quantitative modelling of the Epigenetic - Genetic/Metabolomic - Mental health (EGM) process chain for designing control strategies based on the subjects' personal, environmental, historical, and current state. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06299618
Study type Observational
Source University College Cork
Contact Project Manager
Phone +353(0)21 4205082
Email enigma@ucc.ie
Status Not yet recruiting
Phase
Start date April 2024
Completion date December 2025
View Details
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