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DUAL Antithrombotic Therapy in Patients With AF and ACS

Atrial Fibrillation Clinical Trial

Official title:
An Open-label, Randomized, Controlled, Multicenter Study to Evaluate DUAL Antithrombotic Therapy With Rivaroxaban Plus Ticagrelor vs. Rivaroxaban Plus Clopidogrel in Patients With Atrial Fibrillation and Acute Coronary Syndrome

Clinical Trial Summary

The study aims to show inferiority of rivaroxaban plus ticagrelor when compared to rivaroxaban plus clopidogrel in terms of safety. Safety will be determined by comparing the rates of death or ischemic event-including myocardial infarction, definite or probable stent thrombosis, stroke, or urgent revascularization.

Clinical Trial Description

The main objective of this study is to compare a Dual Antithrombotic Therapy (DAT) regimen of rivaroxaban plus ticagrelor with rivaroxaban plus clopidogrel in Patients With Non Valvular Atrial Fibrillation (NVAF) and Acute Coronary Syndrome. The study aims to show inferiority of rivaroxaban plus ticagrelor when compared to rivaroxaban plus clopidogrel in terms of safety. Safety will be determined by comparing the rates of death or ischemic event-including myocardial infarction, definite or probable stent thrombosis, stroke, or urgent revascularization. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04023630
Study type Interventional
Source Second Affiliated Hospital, School of Medicine, Zhejiang University
Contact Jun Jiang, PhD
Phone 13588706891
Email hu888po@126.com
Status Not yet recruiting
Phase Phase 4
Start date October 1, 2019
Completion date September 30, 2021
View Details
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