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Clinical Trial Details — Status: Terminated

Administrative data

NCT number NCT05643573
Other study ID # 19767
Secondary ID 2023-503794-38-0
Status Terminated
Phase Phase 3
First received
Last updated
Start date December 5, 2022
Est. completion date January 31, 2024

Study information

Verified date February 2024
Source Bayer
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Researchers are looking for a better way to treat people with atrial fibrillation and prevent stroke or systemic embolism (blood clots travelling through the blood stream to plug another vessel). Atrial fibrillation is a condition of having irregular and often rapid heartbeat. It can lead to the formation of blood clots in the heart which can travel through the blood stream to plug another vessel, and like this lead to serious and life-threatening conditions, such as a stroke. A stroke occurs because the brain tissue beyond the blockage no longer receives nutrients and oxygen so that brain cells die. As strokes arising from atrial fibrillation can involve extensive areas of the brain, it is important to prevent them. Blood clots are formed in a process known as coagulation. Medications are already available to prevent the formation of blood clots. When taken by mouth (orally), they are known as oral anticoagulants (OACs) including apixaban. OACs decrease the risk of the above-mentioned serious and life-threatening conditions. The main side effect of OACs is an increase of the risk of bleeding. The study treatment asundexian is a new type of anticoagulant currently under development to provide further treatment options. Asundexian aims to further improve the standard of care with regard to the risk of bleeding. The main purpose of this study is to collect more data about how well asundexian works to prevent stroke and systemic embolism and how safe it is compared to apixaban in people with atrial fibrillation and at high risk for stroke. To see how well the study treatment asundexian works researchers compare: - how long asundexian works well and - how long apixaban works well after the start of the treatment. Working well means that the treatments can prevent the following from happening: - stroke and/or - systemic embolism. The study will keep collecting data until a certain number of strokes or embolisms happen in the study. To see how safe asundexian is, the researchers will compare how often major bleedings occur after taking the study treatments asundexian and apixaban, respectively. Major bleedings are bleedings that have a serious or even life-threatening impact on a person's health. The study participants will be randomly (by chance) assigned to 1 of 2 treatment groups, A and B. Dependent on the treatment group, the participants will either take the study treatment asundexian by mouth once a day or apixaban by mouth twice a day for approximately 9 - 33 months. Each participant will be in the study for approximately 9 - 34 months. There will be visits to the study site every 3 to 6 months and up to 7 phone calls. Those participants who do not want or are unable to have visits to the study site may join the study remotely in selected locations. The location name contains the abbreviation - DCT in such cases. During the study, the study team will: - take blood samples - do physical examinations - examine heart health using an electrocardiogram (ECG) - check vital signs such as blood pressure and heart rate - do pregnancy tests - ask the participants questions about their quality of life - ask the participants questions about how they are feeling and what adverse events they are having. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be related to the study treatments.


Recruitment information / eligibility

Status Terminated
Enrollment 14830
Est. completion date January 31, 2024
Est. primary completion date January 31, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - 18 years of age or older (at legal age of consent according to local legislation) at the time of signing the informed consent - Atrial fibrillation documented by ECG evidence with an indication for indefinite treatment with an oral anticoagulant - CHA2DS2-VASc score = 3 if male or = 4 if female, OR CHA2DS2-VASc score of 2 if male or 3 if female and enrichment criteria. Exclusion Criteria: - Mechanical heart valve prosthesis - Moderate-to-severe mitral stenosis at the time of inclusion into the study - Atrial fibrillation only due to reversible cause - Requirement for chronic anticoagulation for a different indication than AF

Study Design


Related Conditions & MeSH terms


Intervention

Drug:
Asundexian (BAY2433334)
Once a day
Apixaban
5 mg or 2.5 mg, twice a day, according to product label.
Asundexian matching placebo
Placebo to asundexian, once a day
Apixaban matching placebo
Placebo to apixaban, twice a day

Locations

Country Name City State
Argentina Instituto de Investigaciones Clinicas Bahia Blanca Bahía Blanca Buenos Aires
Argentina Centro de Investigaciones Metabólicas Buenos Aires Ciudad Auton. De Buenos Aires
Argentina Centro de Investigaciones Clínicas Caba Ciudad Auton. De Buenos Aires
Argentina Inst. de Cardiología de Corrientes Juana Francisca Cabral Corrientes
Argentina Centro de Investigación y Prevención Cardiovascular General Arenales Buenos Aires
Argentina Hospital Italiano de La Plata | Clinical Research Department La Plata Buenos Aires
Argentina Centro de Investigaciones Medicas Lanus | Research Department Lanus Buenos Aires
Argentina Instituto de Investigaciones Clínicas Mar del Plata Buenos Aires
Argentina Instituto Médico de la Fundación Estudios Clinicos Rosario Santa Fe
Argentina Laboratorio de Hemostasia y Trombosis Rosario Santa Fe
Argentina CardioAlem Investigaciones Monitoreos San Isidro SRL San Isidro Buenos Aires
Argentina Investigaciones Clinicas Tucuman | San Miguel de Tucuman, Argentina San Miguel de Tucumán Tucuman
Argentina Instituto de Investigaciones Clínicas San Nicolás San Nicolás Buenos Aires
Argentina Centro de Investigaciones Clinicas del Litoral Santa Fe
Argentina Centro de Investigaciones Medicas Temperley Temperley Buenos Aires
Argentina Centro de Especialidades Médicas Villa Luro Ciudad Auton. De Buenos Aires
Argentina Instituto de Investigaciones Clínicas Zárate Zárate Buenos Aires
Australia Flinders Medical Centre Adelaide South Australia
Australia Nightingale Research Adelaide South Australia
Australia Royal Adelaide Hospital Adelaide South Australia
Australia Advara HealthCare Wesley Auchenflower Queensland
Australia Grampians Health Ballarat Ballarat Victoria
Australia Sunshine Coast University Hospital Birtinya Queensland
Australia Blacktown Hospital Blacktownn New South Wales
Australia Eastern Health Box Hill Victoria
Australia Royal Brisbane & Women's Hospital Brisbane Queensland
Australia Concord Repatriation General Hospital Concord New South Wales
Australia The Canberra Hospital Garran Australian Capital Territory
Australia Barwon Health Geelong Victoria
Australia The Prince Charles Hospital Herston Queensland
Australia Baker Heart and Diabetes Institute Hoppers Crossing Victoria
Australia Nepean Hospital Kingswood
Australia Advara HealthCare Leabrook Leabrook South Australia
Australia South Western Sydney Local Health District | Liverpool Hospital - Stroke and Neurovascular Department Liverpool New South Wales
Australia Cabrini Malvern Malvern Victoria
Australia Core Research Group Pty Ltd | Brisbane, Australia Milton Queensland
Australia Fiona Stanley Hospital Murdoch Western Australia
Australia John Hunter Hospital New Lambton New South Wales
Australia Royal Melbourne Hospital Parkville Victoria
Australia Advara HealthCare Joondalup Perth Western Australia
Australia The Alfred Hospital Prahran Victoria
Australia Redcliffe District Hospital Redcliffe Queensland
Australia Gold Coast University Hospital Southport Queensland
Australia The Avenue Cardiovascular Centre St Kilda East Victoria
Australia Illawarra Shoalhaven Local Health District Wollongong New South Wales
Australia Queen Elizabeth Hospital AUS Woodville South South Australia
Austria Krankenhaus St. Josef Braunau | Innere Medizin I Braunau Oberösterreich
Austria LKH Feldkirch | Innere Medizin I mit Kardiologie Feldkirch Vorarlberg
Austria MedUni Graz | Kardiologie Graz Steiermark
Austria Landeskrankenhaus Hall | Abteilung fuer Innere Medizin Hall in Tirol Tirol
Austria MedUni Innsbruck | Kardiologie und Angiologie Innsbruck Tirol
Austria Klinikum Klagenfurt | Innere Medizin und Kardiologie Klagenfurt Kärnten
Austria Elisabethinen Linz | Kardiologie, Angiologie & Intensiv Med Linz Oberösterreich
Austria Kepler UK Linz | Kardiologie & Intensivmedizin Campus III Linz Oberösterreich
Austria Landesklinikum Mistelbach|Kardiologie u. Internistische Med Mistelbach Niederösterreich
Austria Uniklinikum Salzburg|Innere Medizin II, Kardiologie Salzburg
Austria UK St. Poelten | Innere Med III St. Poelten Niederösterreich
Austria Klinik Floridsdorf | Herz-, Gefaess- u. Kardio Ambulaz Vienna Wien
Austria MedUni Wien | Innere Medizin II, Kardiologie Vienna Wien
Austria Klinikum Wels-Grieskirchen | Innere Medizin II Wels Oberösterreich
Austria Hanusch Krankenhaus | 2. Medizinische Abteilung Wien
Austria Imed19-privat Wien
Belgium Algemeen Stedelijk Ziekenhuis Campus Aalst Aalst
Belgium OL Vrouwziekenhuis - Campus Aalst Aalst
Belgium ZNA Middelheim Antwerp
Belgium Imeldaziekenhuis - St-Elisabethkliniek / Cardiology Bonheiden Antwerpen
Belgium Algemeen Ziekenhuis Klina | Cardiology Department Brasschaat
Belgium AZ Sint-Jan Brugge-Oostende | Sint-Jan - Cardiology Brugge
Belgium CU Saint-Luc/UZ St-Luc Bruxelles - Brussel
Belgium AZ Sint Blasius, Cardiology, Dendermonde Dendermonde
Belgium UZ Antwerpen - Cardiology Edegem Antwerpen
Belgium Ziekenhuis Oost-Limburg | Genk, Sint-Jan campus - Cardiology Department Genk
Belgium AZ St-Lucas Campus St-Lucas - Cardiology Gent Oost-Vlaanderen
Belgium Maria Middelares General Hospital | Cardiology Department Gent Oost-Vlaanderen
Belgium Grand Hôpital de Charleroi Gilly
Belgium Jessa Ziekenhuis Hasselt
Belgium AZ Groeninge Campus Kennedylaan - Cardiology Kortrijk West-Vlaanderen
Belgium UZ Leuven Gasthuisberg Leuven Vlaams Brabant
Belgium CHR de la Citadelle - Cardiology Liege
Belgium CHC MontLégia Neurology Department Liège
Belgium AZ Sint-Maarten Mechelen
Belgium AZ Delta / Cardiology Roeselare
Belgium Vitaz Sint-Niklaas Moerland Sint-Niklaas
Belgium GZA Ziekenhuizen | Saint Augustine Campus - Cardiology Department Wilrijk Antwerpen
Belgium University Hospital Louvain Namur | Godinne - Cardiology Department Yvoir Namur
Brazil Clínica do Coração Aracaju Sergipe
Brazil Cardresearch Cardilogia Assistencial e de Pesquisas LTDA Belo Horizonte Minas Gerais
Brazil Clínica Procardio Ltda Blumenau Santa Catarina
Brazil UPECLIN - Unidade de Pesquisa Clínica de Botucatu Botucatu Sao Paulo
Brazil Inst. Pesq. Clínica de Campinas - Saraiva & Berlinger Campinas Sao Paulo
Brazil Centro de Pesquisa de São Francisco Curitiba Parana
Brazil Hospital Universitário Evangélico de Curitiba Curitiba Parana
Brazil QUANTA Diagnósticos e Terapia Curitiba Parana
Brazil Hospital das Clínicas de Goiânia Goiânia Goiás
Brazil ICM - Instituto do Coração de Marília Marília Sao Paulo
Brazil Eurolatino Pesquisas Médicas Ltda. Minas Gerais
Brazil Núcleo de Pesquisa Clínica do Hospital Angelina Caron Paraná Parana
Brazil Hospital Maternidade e Pronto Socorro Santa Lucia Poços de Caldas Minas Gerais
Brazil Hospital de Clínicas de Porto Alegre Porto Alegre Rio Grande Do Sul
Brazil Hospital Nossa Senhora da Conceição Porto Alegre Rio Grande Do Sul
Brazil Irmandade Santa Casa de Misericordia de Porto Alegre Porto Alegre Rio Grande Do Sul
Brazil Hospital São Lucas - Rio de Janeiro Rio de Janeiro
Brazil Instituto Cardio Pulmonar da Bahia Salvador Bahia
Brazil Hospital e Maternidade Dr Christóvão da Gama Santo André Sao Paulo
Brazil Hospital de Base | Integrated Research Center São José do Rio Preto Sao Paulo
Brazil Hospital Alemao Oswaldo Cruz Sao Paulo
Brazil Hospital Samaritano Paulista São Paulo Sao Paulo
Brazil Instituto Dante Pazzanese de Cardiologia São Paulo Sao Paulo
Brazil Irmandade da Santa Casa de Misericordia - Sao Paulo São Paulo Sao Paulo
Brazil PUC Campinas São Paulo Sao Paulo
Bulgaria Multiprofile Hospital for Active Treatment Puls | Clinical Trial Center Blagoevgrad
Bulgaria MHAT '' Heart and Brain'' Burgas Burgas
Bulgaria MC Avitsena EOOD Kardzhali
Bulgaria ¿ultidisc. hosp. for act. treatm. Sveti Georgi - Pernik OOD Pernik
Bulgaria Medical centre Hipokrat - N EOOD Plovdiv
Bulgaria Multiprofile Hospital for Active Treatment Medline Clinic Plovdiv
Bulgaria Multiprofile Hospital for Active Treatment Sveta Karidad | Cardiology Department Plovdiv
Bulgaria Medical Center Rusemed Ruse
Bulgaria MHAT Shumen AD Shumen
Bulgaria Multiprofile Hospital for Active Treatment - Silistra Silistra
Bulgaria Diagnostic-Consultative Center XX | Cardiology Department Sofia
Bulgaria FutureMeds | Diagnostic Consultative Center Ascendent Sofia
Bulgaria Medical Center Cardiohelp Sofia
Bulgaria Multiprofile Hospital for Active Treatment Knyaginya Klementina Sofia EAD | Cardiology Department Sofia
Bulgaria Multiprofile Hospital for Active Treatment National Cardiology Hospital | Cardiology Department Sofia
Bulgaria Multiprofile Hospital for Active Treatment Sveta Sofia Sofia
Bulgaria Second Medical Center Sofia EOOD Sofia
Bulgaria Umhatem N. I. Pirogov EAD / Cardiology Sofia
Bulgaria University Hospital for Active Treatment Tsaritsa Joanna - ISUL | Cardiology Clinic Sofia
Bulgaria Medical Center Zara-Med EOOD | Cardiology Department Stara Zagora
Bulgaria Multiprofile Hospital for Active Treatment Trakiya Park | Cardiology Department Stara Zagora
Bulgaria NOVA Clinic Medical Center | Varna, BG Varna
Bulgaria MHAT Dr Stefan Cherkezov Veliko Tarnovo
Canada Viacar Recherches Cliniques Inc. Brossard Quebec
Canada Cambridge Cardiac Care Center Cambridge Ontario
Canada CIUSSS Saguenay Lac-St-Jean Chicoutimi Quebec
Canada Edmonton Cardiology Consultants Edmonton Alberta
Canada University of Alberta Hospital Edmonton Alberta
Canada QEII Health Sciences Centre Halifax Nova Scotia
Canada Hamilton Health Sciences Hamilton Ontario
Canada Hamilton Med.Research Group - DCT Hamilton Ontario
Canada Hamilton Medical Research Group Hamilton Ontario
Canada McMaster University Medical Centre Hamilton Ontario
Canada Interior Health - Royal Inland Hospital Kamloops, British Columbia
Canada Centre intégré de santé et de services sociaux de Laval, Hôp Laval Quebec
Canada London Health Sciences Centre | University Hospital - London Heart Rhythm Program - Cardiology London Ontario
Canada Milestone Research London Ontario
Canada Centricity Research Mirabel Multispecialty Mirabel Quebec
Canada G.A. Research Associates, Ltd. Moncton New Brunswick
Canada CHUM - Centre hospitalier de l'Université de Montréal Montreal Quebec
Canada CIUSSS NÎM Hôpital Sacré-Coeur Montreal Quebec
Canada McGill University Health Centre - Glen Site Montreal Quebec
Canada Montreal Heart Institute Montréal, Quebec
Canada Fraser Clinical Trials, Inc. New Westminster British Columbia
Canada Oakville Cardiovascular Research Oakville Ontario
Canada Dr. James Cha Oshawa Ontario
Canada Kawartha Cardiology Clinical Trials Peterborough Ontario
Canada CHU de Québec-Université Laval Quebec
Canada Institut universitaire de cardiologie et de pneumologie de Q Québec Quebec
Canada Heart Health Institute Scarborough Ontario
Canada CIUSSS de l'Estrie-CHUS, Hopital Fleurimont Sherbrooke Quebec
Canada Niagara Health - St. Catharines Site St. Catharines Ontario
Canada Memorial University of Newfoundland St. John's Newfoundland and Labrador
Canada CISSSL - Hopital Pierre-Le Gardeur Terrebonne Quebec
Canada Sunnybrook Health Sciences Centre Toronto Ontario
Canada Toronto General Hospital UHN Toronto Ontario
Canada Unity Health Toronto: St. Michael's Hospital Toronto Ontario
Canada Women's College Hospital | WCH Main Site - Women's College Research Institute - Cardiology Department Toronto Ontario
Canada Diex Research Trois-Rivières Inc. Trois-Rivieres Quebec
Canada Vancouver General Hospital Vancouver British Columbia
Canada Victoria Heart Institute Foundation Victoria British Columbia
Canada Dr. Louis Yao York Ontario
China Baotou Central Hospital Baotou Inner Mongolia
China The First Affiliated Hospital of Baotou Medical College Baotou Inner Mongolia
China Beijing Anzhen Hospital, Capital Medical University Beijing
China Beijing Chaoyang Hospital, Capital Medical University Beijing
China Beijing Tongren Hospital, Capital Medical University (West) Beijing
China Beijing Tsinghua Changgung Hospital Beijing
China China-Japan Friendship Hospital Beijing
China Peking Union Medical College Hospital CAMS Beijing
China Peking University First Hospital Beijing
China Xuanwu Hospital Capital Medical University Beijing
China Cangzhou Central Hospital Cangzhou Hebei
China China-Japan Union Hospital of Jilin University Changchun Jilin
China The Third Hospital of Changsha Changsha Hunan
China The Third Xiangya Hospital of Central South University Changsha Hunan
China Chengdu Second People's Hospital Chengdu Sichuan
China SichuanAcademyofMedicalSciences&SichuanProvincialPeople'sHos Chengdu Sichuan
China West China Hospital,Sichuan University Chengdu Sichuan
China Daqing Oilfield General Hospital Daqing Heilongjiang
China People's Hospital of Deyang City Deyang Sichuan
China The 1st Affiliated Hospital Fujian Medical University Fuzhou Fujian
China Guangdong Provincial People's Hospital Guangzhou Guangdong
China Guangzhou First People Hospital Guangzhou Guangdong
China Guangzhou Panyu Central Hospital Guangzhou Guangdong
China The 2nd Affiliated Hospital of Guangzhou Medical University Guangzhou Guangdong
China The First Affiliated Hospital of Guangzhou University of TCM Guangzhou Guangdong
China The First Affiliated Hospital of Jinan University Guangzhou Guangdong
China Hainan Provincial People's Hospital Haikou Hainan
China Affiliated Hangzhou First People's Hospital, Zhejiang Univ Hangzhou Zhejiang
China The 1st Affiliated Hospital of Zhejiang University Hangzhou Zhejiang
China The 4th Affiliated Hospital of Harbin Medical University Harbin Heilongjiang
China The First Affiliated Hospital of Harbin Medical University Harbin Heilongjiang
China Inner Mongolia People's Hospital Hohhot Inner Mongolia
China Huai'an First People's Hospital, Nanjing Medical University Huai'An Jiangsu
China Huizhou Central People's Hospital Huizhou Guangdong
China Affiliated Hospital of Jiangsu University JiangSu Jiangsu
China Jinan Central Hospital Jinan Shandong
China Qilu Hospital of Shandong University Jinan Shandong
China The Second Hospital of Shandong University Jinan Shandong
China Affiliated Hospital of Jining Medical University Jining Shandong
China Jining No.1 People's Hospital Jining Shandong
China The First Affiliated Hospital of Jinzhou Medical University Jinzhou Liaoning
China Lanzhou University Second Hospital Lanzhou Gansu
China Liuzhou Worker's Hospital Liuzhou Guangxi
China 1st Affiliated Hospital of Henan Science and Technology Univ Luoyang Henan
China Luoyang Third People's Hospital Luoyang Henan
China Jiangxi Provincial People's Hospital Nanchang Jiangxi
China The First Affiliated Hospital of NanChang University Nanchang Jiangxi
China The Third Hospital of Nanchang Nanchang Jiangxi
China Nanjing First Hospital Nanjing Jiangsu
China Nanjing Jiangning Hospital Nanjing Jiangsu
China The Second Affiliated Hospital of Nanjing Medical university Nanjing Jiangsu
China Zhongda Hospital Southeast University Nanjing Jiangsu
China Hwa Mei Hospital, University of Chinese Academy Sciences Ningbo Zhejiang
China Ningbo First Hospital Ningbo Zhejiang
China Panjin Liaohe Oilfield Gem Flower Hospital Panjin Liaoning
China PingXiang People's Hospital Pingxiang Jiangxi
China Hainan Third People's Hospital (Province Nongken Sanya Hopt) Sanya Hainan
China Huashan Hospital, Fudan University Shanghai
China Shanghai General Hospital Shanghai
China Shanghai Putuo District Central Hospital Shanghai
China Zhongshan Hospital, Fudan University Shanghai
China The First Hospital of Hebei Medical Univesity Shijiazhuang Hebei
China Taian City Central Hospital Taian Shandong
China Shanxi Bethune Hospital Taiyuan Shanxi
China Shanxi Candiovascular Hospital Taiyuan Shanxi
China Taizhou Hospital of Zhejiang Province Taizhou Zhejiang
China Taizhou People's Hospital Taizhou Jiangsu
China Teda International Cardiovascular Hospital Tianjin
China Tianjin People's Hospital Tianjin
China Tonghua Central Hospital Tonghua Jilin
China The First Affiliated Hospital of Xinjiang Medical University Urumchi Xinjiang
China The First Affiliated Hospital of Wenzhou Medical University Wenzhou Zhejiang
China Union Hospt Tongji Medical Colleg. Huazhong univ. Scien&Tech Wudan Hubei
China Renmin Hospital of Wuhan University Wuhan Hubei
China The Central Hospital of Wuhan, Tongji Medl Collg Huazhong... Wuhan Hubei
China Wuhan No. 4 Hospital Wuhan Hubei
China Shaanxi Provincial People's Hospital Xi'an Shanxi
China Xiamen Cardiovascular Hospital Xiamen University Xiamen Fujian
China Yan'an University Xianyang Hospital Xianyang Shaanxi
China Qinghai University Affiliated Hospital Xining Qinghai
China Xinxiang Central Hospital Xinxiang Henan
China Northern Jiangsu People's Hospital Yangzhou Jiangsu
China Yangzhou No. 1 People's Hospital (West Hospital) Yangzhou Jiangsu
China General Hospital of Ningxia Medical University Yinchuan Ningxia
China The First People's Hospital of Yinchuan Yinchuan Ningxia
China Yuncheng Central Hospital Yuncheng Shanxi
China The First affiliated Hospital of Hebei North University Zhangjiakou Hebei
China Zibo Central Hospital Zibo Shandong
Czechia Amkardia s.r.o. Brno
Czechia Fakultni nemocnice Brno Brno
Czechia Kardiologicka ambulance Brno s.r.o. Brno
Czechia Vojenska nemocnice Brno Brno
Czechia Kardiologicka ambulance Cormedico Bruntal
Czechia Nemocnice Ceske Budejovice, a.s. Department of kardiologie Ceske Budejovice
Czechia Mrozek kardiologie Frydek-Mistek
Czechia MATMED s.r.o. Hodonin
Czechia Krajska Nemocnice Liberec Liberec
Czechia Fakultni Nemocnice Olomouc Olomouc
Czechia Benedor s.r.o. Ostrava - Poruba
Czechia MUDr. Michalik s.r.o. Ostrava-Zabreh
Czechia Fakultni nemocnice Plzen Plzen
Czechia Cevni Kulatak Praha
Czechia Fakultni nemocnice Kralovske Vinohrady Praha 10
Czechia Institut Klinicke a Experimentalni Mediciny Praha 4
Czechia Fakultni nemocnice v Motole Praha 5
Czechia Medicon Poliklinika Holesovice Praha 7
Czechia Nemocnice Slany Slany
Czechia Cardio Research s.r.o. Zlin
Denmark Region Nordjylland | Aalborg University Hospital - Cardiology Department Aalborg
Denmark Region Midtjylland | Aarhus University Hospital - Heart Diseases - Clinical Research Århus N
Denmark Capital Region | Amager Hospital - Cardiology Outpatient Clinic Copenhagen
Denmark Sydvestjysk Sygehus Esbjerg | Kardiologisk Forskningsenhed Esbjerg
Denmark Capital Region | Frederiksberg Hospital - Department of Cardiology Research Frederiksberg
Denmark Capital Region | Gentofte Hospital - Cardiology Research Hellerup
Denmark Capital Region | Herlev Hospital - Department of Heart Disease Herlev
Denmark Region Midtjylland | Regionshospitalet Godstrup - Clinic for Heart Research Herning
Denmark Nordsjaellands Hospital | Hillerod - Cardiology Department Hilleroed
Denmark Region Nordjylland | Hjoerring - Cardiology Department Hjørring
Denmark Holbæk Sygehus Holbæk
Denmark Capital Region | Hvidovre Hospital - Department of Cardiology Hvidovre
Denmark Sygehus Lillebaelt | Kolding Sygehus - Medicinske Sygdomme Kolding
Denmark Sjællands Universitetshospital Roskilde Roskilde
Denmark Odense University Hospital | Svendborg Hospital - Cardiovascular Research Unit Svendborg
Denmark Region Midtjylland | Viborg Regional Hospital - Cardiology - Heart Research Viborg
Estonia Dr Signe Alliksoo Family Doctors Practice Tallinn
Estonia East Tallinn Central Hospital Tallinn
Estonia North Estonia Medical Centre Foundation Tallinn
Estonia Office of Arvo Rosenthal Tallinn
Estonia Pirita Family Doctors Centre Tallinn
Estonia West Tallinn Central hospital Tallinn
Estonia Tartu University Hospital Tartu
Finland HUS Jorvin sairaala Espoo
Finland StudyCor Oy Jyväskylä
Finland Health Step Finland Oy Kuopio
Finland Kuopion yliopistollinen sairaala Kuopio
Finland Oulun yliopistollinen sairaala Oulu
Finland Tays Sydänsairaala Tampere
Finland Turun yliopistollinen keskussairaala Turku
France Centre Hospitalier Universitaire - Angers Angers
France Centre Hospitalier Intercommunal de la Côte Basque-Bayonne Bayonne
France Hopital Charles Nicolle Chu Rouen Bois-Guillaume
France Hôpital La Cavale Blanche - CHU de Brest Brest
France Hôpital Louis Pradel - Bron Bron
France CHU de Caen - Hôpital Côte de Nacre CAEN cedex 9
France Hôpital Trousseau - Tours Chambray-lès-Tours
France Centre Hospitalier - Cholet Cholet
France Hôpital Henri Mondor Creteil
France CHU GRENOBLE - Hopital Michallon GRENOBLE Cedex 09
France Centre Hospitalier Départemental Vendée LA ROCHE SUR YON cedex
France Centre Hospitalier Louis Pasteur Le Coudray
France Centre Hospitalier du Docteur Schnaffer - Lens Lens
France Hôpital Dupuytren Limoges Cedex
France Hôpital Guillaume et René Laennec - Nantes Nantes
France Nouvelles Cliniques Nantaises - Nantes NANTES cedex 2
France Hôpital Pasteur - Nice Nice
France Hopital Carémeau - Nîmes Nîmes
France Hôpital de la Pitié-Salpétrière Paris
France Institut Mutualiste Montsouris Paris
France Hopital Européen Georges Pompidou - Paris Paris Cedex 15
France Hôpital Cardiologique - Pessac Pessac
France CHU Rennes, H Pontchaillou, Cardiologie Rennes
France Centre Hospitalier Régional - Saint Brieuc Saint Brieuc
France Hôpital Civil - Strasbourg Strasbourg
France CHI Toulon - H La Seyne - Cardiologie Toulon
France Clinique Pasteur - Toulouse Toulouse
France Hôpital de Rangueil - Toulouse TOULOUSE cedex
France Centre Hospitalier Gustave Dron - Tourcoing Tourcoing
France Centre Hospitalier - Valenciennes Cedex Valenciennes
France Centre Hospitalier Universitaire de Nancy Vandoeuvre-les-nancy
Germany UniKlinikum Aachen|Kardio, Angio, Intensivmedizin Aachen Nordrhein-Westfalen
Germany Universitaets Herzzentrum Bad Krozingen Bad Krozingen Baden-Württemberg
Germany St.Johannes-Hospital|Klinik fuer Innere Medizin I Dortmund Nordrhein-Westfalen
Germany Krankenhaus Dresden-Friedrichstadt Dresden Sachsen
Germany Pratia | Klinische Forschung Dresden Dresden Sachsen
Germany Zentrum für klinische Prüfungen Dresden Sachsen
Germany Ev. Krankenhaus Hagen-Haspe|Kardiologie und Rhythmologie Hagen Nordrhein-Westfalen
Germany Cardiologicum Hamburg Hamburg
Germany Klinische Forschung Hamburg GmbH Hamburg
Germany Uniklinikum Hamburg-Eppendorf|Klinik für Kardiologie Hamburg
Germany Medizinische Hochschule Hannover|Kardiologie und Angiologie Hannover Niedersachsen
Germany Uni-Klinikum Heidelberg | Kardiologie Angiologie Pneumologie Heidelberg Baden-Württemberg
Germany Uniklinik Jena / Kardiologie Jena Thüringen
Germany St. Vinzenz-Hospital|Innere Medizin III, Kardiologie Koeln Nordrhein-Westfalen
Germany MEDICLIN Herzzentrum Lahr|Kardiologie Lahr Baden-Württemberg
Germany Uniklinik Leipzig / Kardiologie Leipzig Sachsen
Germany Klinikum Lüdenscheid - Märkische Kliniken GmbH Lüdenscheid Nordrhein-Westfalen
Germany Cardio Centrum Ludwigsburg Ludwigsburg Baden-Württemberg
Germany Universitätsmedizin der Johannes Gutenberg Universität Mainz Mainz Rheinland-Pfalz
Germany Praxis Hr. Dr. med. Jens Taggeselle Markkleeberg Sachsen
Germany Kliniken Maria Hilf GmbH Mönchengladbach Nordrhein-Westfalen
Germany Sana-Klinikum Remscheid|Kardio, Angio, Pneumo u. Intensivmed Remscheid Nordrhein-Westfalen
Germany Hegau-Bodensee-Klinikum Singen|I. Medizinische Klinik Singen Baden-Württemberg
Germany Siteworks Pruefzentrum Voelklingen Voelklingen Saarland
Germany Josephs-Hospital|Kardiologie, Rhythmologie und Angiologie Warendorf Nordrhein-Westfalen
Germany Kardiologische Praxis Hr. Dr. A. Al-Zoebi Wermsdorf Sachsen
Germany Forschungszentrum Ruhr KliFoCenter GmbH Witten Nordrhein-Westfalen
Germany Klinikum Worms gGmbH|Kardiologie und Angiologie Worms Rheinland-Pfalz
Greece University General Hospital of Alexandroupolis Alexandroupoli
Greece EVANGELISMOS General Hospital of Athens Athens
Greece G. GENNIMATAS General State Hospital of Athens Athens
Greece General Hospital of Athens "ALEXANDRA" Athens
Greece HIPPOKRATION General Hospital of Athens Athens
Greece LAIKO General Hospital of Athens Athens
Greece Naval Hospital of Athens Athens
Greece University General Hospital ATTIKON Chaidari
Greece Thriassio General Hospital of Elefsina Elefsina
Greece University General Hospital of Heraklion Heraklion
Greece Ioannina University General Hospital Ioannina
Greece KAT General Hospital of Athens Kifisia / Athens Attica
Greece Univ. General Hospital of Larissa Larissa
Greece University General Hospital of Larissa Larissa
Greece MITERA Hospital Maroussi
Greece Konstantopoulio General Hospital of Nea Ionia - AGIA OLGA Nea Ionia / Athens
Greece University General Hospital of Patra Patra
Greece AHEPA University General Hospital of Thessaloniki Thessaloniki
Greece Hippokration General Hospital of Thessaloniki Thessaloniki
Greece General Hospital ASKLEPIEIO VOULAS Voula
Hungary Cardiomobile Egeszsegugyi Szolgaltato Kft. Balatonfured
Hungary Budapesti Jahn Ferenc Del-pesti Korhaz es Rendelointezet Budapest
Hungary Budapesti Uzsoki Utcai Korhaz Budapest
Hungary Semmelweis University Budapest
Hungary Belinus Bt. Debrecen
Hungary Kardio Egeszseghaz - Dr Amer Sayour Egyeni Vallakozo Gyor
Hungary Trial Pharma Kft. Gyula Gyula
Hungary Somogy Varmegyei Kaposi Mor Oktato Korhaz Kaposvar
Hungary Komaromi Selye Janos Korhaz Komarom
Hungary Borsod-Abauj-Zemplen Varmegyei Korhaz es Egyetemi Oktatokorhaz Miskolc
Hungary TaNa Med Kft. Mosonmagyarovar
Hungary Kanizsai Dorottya Hospital Nagykanizsa
Hungary Borbanya Praxis Bt. Nyiregyhaza
Hungary Medifarma-98 Egeszsegugyi, Kereskedelmi es Szolgaltato Kft. Nyiregyhaza
Hungary Dr. Nagy Laszlo Egyeni Egeszsegugyi Vallalkozo Oroshaza
Hungary Oroshaza Hospital Oroshaza
Hungary Coromed Smo Kft Pecs
Hungary Pecsi Tudomanyegyetem Klinikai Kozpont Pecs
Hungary Complex Rendelo Med Zrt. Szekesfehervar
Hungary Tolna Varmegyei Balassa Janos Korhaz Szekszard
Hungary Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz Szombathely
Hungary Belvarosi Egeszseghaz Kft. Zalaegerszeg
India The Institute of Post Graduate Medical Education & Research (IPGMER) (SSKM Hospital) Calcutta
India Asian Institute of Gastroenterology (AIG Hospital) Hyderabad
India Lisie Hospital Kochi Kerala
India Vijan Cardiac & Critical Care Centre Nashik Maharashtra
India All India Institute of Medical Sciences (AIIMS) - New Delhi New Delhi
India Sir Gangaram Hospital, Delhi New Delhi
India Vardhman Mahavir Medical College & Safdarjung Hospital (VMMC-SJH) New Delhi
India King Edward Memorial (KEM) Hospital - Pune Pune
India Shri B.D. Mehta Mahavir Heart Institute Surat
Israel Clalit Health Services through HaEmek Medical Center Afula
Israel Assuta Ashdod Ashdod
Israel Barzilai Ashkelon University Medical Center | Cardiology Department Ashkelon
Israel Assuta Beer Sheva Beer Sheva
Israel Soroka University Medical Center Beer Sheva
Israel Hillel Yaffe Medical Center Hadera
Israel Bnai Zion Medical Center Haifa
Israel Lady Davis Carmel Medical Center Haifa
Israel Rambam Health Corporation Haifa
Israel Edith Wolfson Medical Center Holon
Israel Hadassah Hebrew University Hospital Ein Kerem Jerusalem
Israel Shaare Zedek Medical Center Jerusalem
Israel Meir Medical Center Kfar Saba
Israel Poriya Medical Center | Cardiology Department Lower Galilee
Israel Health Corporation of Galilee Medical Center Nahariya
Israel Clalit Health Services Rabin Medical Center-Beilinson Campus Petach Tikva
Israel Clalit Health Services Rabin Medical Center-Beilinson Campus Petah Tikva
Israel Chaim Sheba Medical Center Ramat Gan
Israel Kaplan Medical Center Rehovot
Israel Tel-Aviv Sourasky Medical Center Tel Aviv
Israel Health Corporation of the Ziv Medical Center (R.A.) Zefat
Israel Shamir Medical Center (Assaf Harofeh) Zrifin
Italy A.O.U. Ospedali Riuniti "Umberto I - G.M.Lancisi - G.Salesi" Ancona Marche
Italy AUSL Toscana Sud-Est Arezzo Toscana
Italy ASUR Marche - Area Vasta 5 Ascoli Piceno Marche
Italy Ente Ecclesiastico Ospedale Generale Regionale Miulli Bari Puglia
Italy ASST Papa Giovanni XXIII Bergamo Lombardia
Italy AUSL di Bologna Bologna Emilia-Romagna
Italy ASST del Garda Brescia Lombardia
Italy A.O Sant'Anna-San Sebastiano Caserta Campania
Italy ASL2 Lanciano-Vasto-Chieti Chieti Abruzzo
Italy A.O.U. di Ferrara Ferrara Emilia-Romagna
Italy A.O.U. Careggi Firenze Toscana
Italy A.O.U. Ospedali Riuniti Foggia Foggia Puglia
Italy IRCCS Centro Cardiologico Monzino S.p.A Milano Lombardia
Italy Istituto Clinico Humanitas - Humanitas Mirasole S.p.A. Milano Lombardia
Italy A.O.U. di Modena - Policlinico Modena Emilia-Romagna
Italy A.O.R.N. Ospedali dei Colli (Monaldi-Cotugno-CTO) Napoli Campania
Italy A.O.U. Policlinico Federico II Napoli Napoli Campania
Italy A.O.U. Maggiore della Carità Novara Piemonte
Italy A.O.U. di Padova Padova Veneto
Italy A.O.U. di Parma Parma Emilia-Romagna
Italy A.O. di Perugia Perugia Umbria
Italy A.O.U. Pisana Pisa Toscana
Italy A.O.U. Policlinico Umberto I Roma Lazio
Italy Asl Roma 2 Roma Lazio
Italy ULSS2 Marca Trevigiana Treviso Veneto
Italy ASST Sette Laghi Varese Lombardia
Italy ULSS3 Serenissima Venezia Veneto
Japan Ageo Central General Hospital Ageo Saitama
Japan Akashi Medical Center Akashi Hyogo
Japan Mazda Hospital of Mazda Motor Corporation Aki-gun Hiroshima
Japan Hyogo Prefectural Amagasaki General Medical Center Amagasaki Hyogo
Japan Asahikawa City Hospital Asahikawa Hokkaido
Japan Japan Red Cross Society Azumino Hospital Azumino Nagano
Japan Tokyo Medical and Dental University Hospital Bunkyo-ku Tokyo
Japan Tokyo-Eki Center-building Clinic Chuo-ku Tokyo
Japan Fujisawa City Hospital Fujisawa Kanagawa
Japan Fukui General Clinic Fukui
Japan Fukui Prefectural Hospital Fukui
Japan Fukuoka University Hospital Fukuoka
Japan Fukuoka University Nishijin Hospital Fukuoka
Japan Kyushu Central Hospital Fukuoka
Japan Social Medical Corporation the Chiyukai foundation Fukuoka Wajiro Hospital Fukuoka
Japan Munakata Suikokai General Hospital Fukutsu Fukuoka
Japan Chiba Tokushukai Hospital Funabashi Chiba
Japan Gifu Heart Center Gifu
Japan Minamino Cardiovascular Hospital Hachioji Tokyo
Japan Tokyo Angel Hospital Hachioji Tokyo
Japan Hakodate Municipal Hospital Hakodate Hokkaido
Japan Hakodate National Hospital Hakodate Hokkaido
Japan Public Central Hospital of Matto Ishikawa Hakusan Ishikawa
Japan National Hospital Organization Hamada Medical Center Hamada Shimane
Japan National hospital Organization Mito Medical Center Higashiibaraki Ibaraki
Japan Hyogo Prefectural Harima-Himeji General Medical Center Himeji Hyogo
Japan Hiroshima City Hiroshima Citizens Hospital Hiroshima
Japan Iida Hospital Iida Nagano
Japan Nippon Medical School Chiba Hokusoh Hospital Inzai Chiba
Japan Nihon University Itabashi Hospital Itabashi-ku Tokyo
Japan Nakamura Cardiovascular Clinic Itoshima Fukuoka
Japan Kagoshima Medical Center Kagoshima
Japan Tenyoukai Central Clinic Kagoshima
Japan Kanazawa Medical University Hospital Kahoku-gun Ishikawa
Japan Ishikawa Prefectural Central Hospital Kanazawa Ishikawa
Japan National Hospital Organization Kanazawa Medical Center Kanazawa Ishikawa
Japan Mitoyo General Hospital Kanonji Kagawa
Japan Oosumikanoya Hospital Kanoya Kagoshima
Japan Ibaraki Prefectural Central Hospital Kasama Ibaraki
Japan Kasugai Municipal Hospital Kasugai Aichi
Japan Kawaguchi Cardiovascular and Respiratory Hospital Kawaguchi Saitama
Japan The Veritas Hospital Kawanishi Hyogo
Japan Kimitsu Chuo Hospital Kisarazu Chiba
Japan Kishiwada Tokushukai Hospital Kishiwada Osaka
Japan North Alps Medical Center Azumi Hospital Kitaazumi-gun Nagano
Japan Kokura Memorial Hospital Kitakyushu Fukuoka
Japan Steel Memorial Yawata Hospital Kitakyushu Fukuoka
Japan Kobe City Medical Center General Hospital Kobe Hyogo
Japan Chikamori Hospital Kochi
Japan Yamanashi Prefectural Central Hospital Kofu Yamanashi
Japan Komatsu Municipal Hospital Komatsu Ishikawa
Japan Asama Nanroku Komoro Medical Center Komoro Nagano
Japan Kumamoto Kinoh Hospital Kumamoto
Japan National Hospital Organization Kyoto Medical Center Kyoto
Japan Rakuwakai Otowa Hospital Kyoto
Japan Machida Municipal Hospital Machida Tokyo
Japan Matsuyama Shimin Hospital Matsuyama Ehime
Japan National Hospital Organization Tokyo Medical Center Meguro-ku Tokyo
Japan Tokyo Saiseikai Central Hospital Minato Tokyo
Japan Mito Saiseikai General Hospital Mito Ibaraki
Japan Hayama Heart Center Miura-gun Kanagawa
Japan Miyazaki Medical Association Hospital Miyazaki
Japan Iwate Prefectural Central Hospital Morioka Iwate
Japan Japan Community Healthcare. Organization Chukyo Hospital Nagoya Aichi
Japan Japanese RedCross Aichi Medical Center Nagoya Daini Hospital Nagoya Aichi
Japan R.I.A.C Naha City Hospital Naha Okinawa
Japan Go Neurosurgical Clinic Nakagawa Fukuoka
Japan Hokushin General Hospital Nakano Nagano
Japan Oita Prefectural Hospital Oita
Japan Okayama City General Medical Center Okayama City Hospital Okayama
Japan Okayama Rosai Hospital Okayama
Japan The Sakakibara Heart Institute of Okayama Okayama
Japan Omihachiman Community Medical Center Omihachiman Shiga
Japan Fukuoka Shin Mizumaki Hospital Onga-gun Fukuoka
Japan Onga Nakama Medical Association Onga Hospital Onga-gun Fukuoka
Japan Japan Community Health Care Organization Osaka Hospital Osaka
Japan Kitada Clinic Osaka
Japan Nippon Life Hospital Osaka
Japan Osaka Police Hospital Osaka
Japan Osaka Saiseikai Nakatsu Hospital Osaka
Japan Sakurabashi Watanabe Hospital Osaka
Japan Saga Memorial Hospital Saga
Japan Iwatsuki-minami Hospital Saitama
Japan Sainokuni Higashiomiya Medical Center Saitama
Japan Sanai hospital Saitama
Japan Toho University Sakura Medical Center Sakura Chiba
Japan Hanaoka Seishu Memorial Hospital Sapporo Hokkaido
Japan Matsuda Cardiovascular clinic Sapporo Hokkaido
Japan Mita Internist and Cardiology Clinic Sapporo Hokkaido
Japan Miyanomori Memorial Hospital Sapporo Hokkaido
Japan Miyanosawa Clinic of Internal Medicine and Cardiology Sapporo Hokkaido
Japan Sapporo Higashi Tokushukai Hospital Sapporo Hokkaido
Japan Teine Keijinkai Hospital Sapporo Hokkaido
Japan Sendai Cardiovascular Center Sendai Miyagi
Japan Tohoku Medical and Pharmaceutical University Hospital Sendai Miyagi
Japan Dokkyo Medical University Hospital Shimotsuga-gun Tochigi
Japan Tokyo Yamate Medical Center Shinjuku-ku Tokyo
Japan Shirakawa Kosei General Hospital Shirakawa Fukushima
Japan Shizuoka City Shizuoka Hospital Shizuoka
Japan JCHO Tokuyama Central Hospital Shunan Yamaguchi
Japan NewHeart Watanabe Institute Suginami-ku Tokyo
Japan Osaka Saiseikai Senri Hospital Suita Osaka
Japan Japanese Red Cross Society Suwa Hospital Suwa Nagano
Japan Suzuka Chuo General Hospital Suzuka Mie
Japan National Hospital Organization Disaster Medical Center Tachikawa Tokyo
Japan Kagawa Prefectural Central Hospital Takamatsu Kagawa
Japan Higashi Takarazuka Satoh Hospital Takarazuka Hyogo
Japan National Hospital Organization Takasaki General Medical Center Takasaki Gunma
Japan Oji General Hospital Tomakomai Hokkaido
Japan Tomakomai City Hospital Tomakomai Hokkaido
Japan JA Toride Medical Center Toride Ibaraki
Japan Toyota Kosei Hospital Toyota Aichi
Japan Tsuchiura Kyodo General Hospital Tsuchiura Ibaraki
Japan Urasoe General Hospital Urasoe Okinawa
Japan Saiseikai Wakayama Hospital Wakayama
Japan Yanagawa Hospital Yanagawa Fukuoka
Japan Yao Tokushukai General Hospital Yao Osaka
Japan Yokohama City University Medical Center Yokohama Kanagawa
Japan Yokohama Sakae Kyosai Hospital Yokohama Kanagawa
Korea, Republic of Hallym University Sacred Heart Hospital Anyang Gyeonggido
Korea, Republic of The Catholic University of Korea Seoul St. Mary's Hospital Bucheon-si, Gyeonggido
Korea, Republic of Dong-A University Hospital Busan
Korea, Republic of Pusan National University Hospital Busan Busan Gwang''yeogsi
Korea, Republic of Keimyung University Dongsan Medical Center Daegu
Korea, Republic of Kyungpook National University Hospital Daegu Daegu Gwang''yeogsi
Korea, Republic of Chonnam National University Hospital Gwangju
Korea, Republic of Gachon University Gil Medical Center Incheon
Korea, Republic of Korea University Anam Hospital Seongbuk
Korea, Republic of Bundang Cha Hospital Seongnam-si Gyeonggido
Korea, Republic of Seoul National University Bundang Hospital Seongnam-si Gyeonggido
Korea, Republic of Asan Medical Center Seoul
Korea, Republic of Chung-Ang University Hospital Seoul
Korea, Republic of Samsung Medical Center Seoul
Korea, Republic of Seoul National University Hospital Seoul
Korea, Republic of Severance Hospital, Yonsei University Health System Seoul
Korea, Republic of The Catholic Univ. of Korea Eunpyeong St. Mary's Hospital Seoul Seoul Teugbyeolsi
Korea, Republic of Ajou University Hospital Suwon Gyeonggido
Korea, Republic of Uijeongbu ST. Mary's Hospital Uijeongbu Gyeonggido
Korea, Republic of Yonsei University Wonju Christian Hospital Wonju Gang''weondo
Latvia Daugavpils Regional Hospital Daugavpils
Latvia Doctor's Practice in Cardiology Daugavpils
Latvia SIA ARI Med Daugavpils
Latvia Rutas Eglites GP Practice Kuldiga
Latvia Liepaja Regional Hospital Liepaja
Latvia Lija Mora physician practice Ogre
Latvia 1st Riga Clinical Hospital Riga
Latvia APS Clinic Riga
Latvia Health Center 4 Riga
Latvia Health Center Adoria Riga
Latvia P. Stradins Clinical University Hospital Riga
Latvia Riga East Clinical University Hospital "Gailezers" Riga
Latvia Vidzemes Hospital Valmiera
Latvia Gita Rancane - cardiology private practice Ventspils
Lithuania Hospital of LT University of Health Sciences Kaunas Clinics Kaunas
Lithuania InMedica clinic Zaliakalnis Kaunas
Lithuania Kardiolitos klinikos / BMP Kaunas
Lithuania LUHS Kauno Hospital (Josvainiu str.) Kaunas
Lithuania LUHS Kauno Hospital (Laisves ave.) Kaunas
Lithuania Mariu klinika JSC Kaunas
Lithuania Saules family medicine center Kaunas
Lithuania Kardiologijos ir reabilitacijos klinika Klaipeda
Lithuania Klaipeda Republican Hospital Klaipeda
Lithuania Klaipeda Seamen's Hospital Klaipeda
Lithuania Klaipeda Seamen's Hospital Cardiology Department I Klaipeda
Lithuania Siauliai Republican hospital Siauliai
Lithuania InMedica Clinic Santariskes Vilnius
Lithuania Vilnius University Hospital Santaros Klinikos Vilnius
Malaysia Hospital Sultanah Bahiyah Alor Setar
Malaysia University Hospital Kebangsaan Malaysia Cheras
Malaysia Hospital Sultanah Aminah Johor Bahru
Malaysia Hospital Raja Perempuan Zainab II Kelantan
Malaysia Hospital Universiti Sains Malaysia Kelantan
Malaysia Institute Jantung Negara Kuala Lumpur
Malaysia University Malaya Medical Centre Kuala Lumpur
Malaysia Hospital Tengku Ampuan Afzan Pahang
Malaysia Hospital Seberang Jaya Pulau Pinang
Malaysia Sarawak General Hospital Sarawak
Malaysia Sarawak Heart Centre Sarawak
Malaysia Hospital Al-Sultan Abdullah (UiTM Hospital) Selangor
Malaysia Hospital Pengajar Universiti Putra Malaysia Selangor
Malaysia Hospital Serdang Selangor
Malaysia Seremban Hospital Neurology Seremban
Netherlands Ziekenhuis Amstelland Amstelveen
Netherlands Academisch Medisch Centrum (AMC) Amsterdam
Netherlands Gelre Ziekenhuizen Apeldoorn / Cardiology Apeldoorn
Netherlands Rijnstate | Arnhem - Internal Medicine Department - Vascular Research Arnhem
Netherlands Rode Kruis Ziekenhuis Beverwijk
Netherlands Tergooiziekenhuizen-Blaricum Blaricum
Netherlands Amphia Breda | Department of Cardiology, BMC Research Breda
Netherlands HagaZiekenhuis | Cardiology Department Den Haag
Netherlands Van Weel-Bethesda Ziekenhuis Dirksland
Netherlands Albert Schweitzer Ziekenhuis, Dordwijk Dordrecht
Netherlands Catharina Hospital | Cardiology Department Eindhoven
Netherlands Treant locatie Bethesda Emmen
Netherlands MST|TCT-Foundation Cardiovascular Research and Education Enschede
Netherlands Admiraal de Ruyterziekenhuis Goes Zeeland
Netherlands Beatrixziekenhuis Gorinchem
Netherlands Martini Ziekenhuis, Locatie van Swieten Groningen
Netherlands Universitair Medisch Centrum Groningen Groningen
Netherlands Spaarne Gasthuis - locatie Zuid Haarlem
Netherlands Saxenburgh Medisch Centrum Hardenberg
Netherlands Bravis Ziekenhuis Roosendaal
Netherlands Ziekenhuis Rivierenland | Cardiology Research Department Tiel
Netherlands VieCuri - Medisch Centrum voor Noord-Limburg locatie Venlo Venlo
Netherlands Zaans Medisch Centrum Zaandam
Norway Ålesund Sykehus, Kardiologisk Seksjon Ålesund
Norway Nordlandssykehuset HF Bodø
Norway Vestre Viken HF - Drammen Sykehus Cardiology Drammen
Norway Sykehuset Innlandet HF Elverum Elverum
Norway Sykehuset Østfold HF Fredrikstad Fredrikstad
Norway Vestre Viken HF - Bærum Sykehus Cardiology Gjettum
Norway Sykehuset Innlandet HF Gjøvik Gjøvik
Norway Universitetssykehuset i Nord Norge, Harstad Harstad
Norway Sykehuset Innlandet HF Lillehammer Lillehammer
Norway Helse Møre og Romsdal HF Molde
Norway Akershus University Hospital Cardiology Department Nordbyhagen
Norway Diakonhjemmets sykehus Oslo
Norway Oslo Universitetssykehus HF, Rikshospitalet Oslo
Norway OUS Ullevål Cardiology Department Oslo
Norway Skedsmo Medisinske Senter Skedsmokorset
Norway Stavanger Universitetssjukehus Stavanger
Norway Universitetssykehuset Nord-Norge HF Tromsø Tromsø
Poland KLIMED Marek Klimkiewicz Bialystok
Poland Uniwersytecki Szpital Kliniczny w Bialymstoku Bialystok
Poland Centrum Medyczne KerMed Bydgoszcz
Poland MICS Centrum Medyczne Bydgoszcz Bydgoszcz
Poland Uniwersyteckie Centrum Kliniczne Gdansk
Poland Samodzielny Publiczny Specjalistyczny Szpital Zachodni Grodzisk Mazowiecki
Poland CLINICAL MEDICAL RESEARCH Sp. z o. o. Katowice
Poland Vita Longa Sp. z o.o. Katowice
Poland Unicardia Specjalistyczne Centrum Leczenia Ch.Serca i Naczyn Krakow
Poland Centrum Terapii Wspolczesnej Lodz
Poland MED-GASTR Sp. z o.o. Sp. k. Lodz
Poland Centrum Medyczne Ogrodowa G. i M. Kania Lekarze i Lekarze Dentysci Spólka Partnerska z siedziba w Skierniewicach Lowicz
Poland 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie Lublin
Poland NZOZ "Twoja Przychodnia" Sp. z o.o. Lublin
Poland Etyka Osrodek Badan Klinicznych Olsztyn
Poland Futuremeds sp. z o. o. Olsztyn
Poland NZOZ Heureka Piaseczno
Poland Irmed Klimkiewicz, Rudziewicz-Kowalska Sp.j. Piotrkow Trybunalski
Poland Solumed Centrum Medyczne Poznan
Poland KO-MED Centra Kliniczne Pulawy Pulawy
Poland EMED Centrum Uslug Medycznych Ewa Smialek Rzeszow
Poland ClinMedica Research Sp. z o.o. Skierniewice
Poland "Nowe Zdrowie-Ck" Kieltucki I Wspolnicy Spolka Jawna Staszow
Poland Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji Warszawa
Poland NBR Polska Tomasz Klodawski Warszawa
Poland KO-MED Centra Kliniczne Zamosc Zamosc
Portugal Hospital Garcia de Orta | Research Department Almada
Portugal Centro Clinico Academico Braga | Braga, Portugal Braga
Portugal Centro Hospitalar e Universitario de Coimbra, E.P.E. | Department of Cardiology, Research Unit Coimbra
Portugal Centro Hospitalar Universitario Cova de Beira | Clinical Research Department Covilha Castelo Branco
Portugal Centro Hospitalar de Tamega e Sousa | Hospital Padre Americo - Cardiology Department Guilhufe
Portugal Hospital da Senhora da Oliveira | Clinical Research Department Guimaraes, Braga Braga
Portugal Centro Hospitalar de Leiria | Santo Andre Hospital - Research Center Leiria
Portugal Centro Hospitalar de Lisboa Ocidental | Clin Res Dept Lisboa
Portugal Centro Hospitalar Universitário de Lisboa Norte | Heart and Vessels Department Lisboa
Portugal Lusiadas | Hospital Lusiadas Lisboa - Lusiadas Knowledge Center Lisboa
Portugal Luz Saude | Hospital da Luz Lisboa - Centro de Investigacao Clinica Lisboa
Portugal ULSM - Hospital Pedro Hispano Matosinhos Porto
Portugal CHUSJ - Hospital Sao Joao Porto
Portugal Ucardio | Cardiology Department Riachos Santarém
Portugal Hospital da Luz - Setubal Setubal Setúbal
Portugal Centro Hospitalar Vila Nova de Gaia/Espinho | Unit 1 - Clinical Research Office Vila Nova de Gaia
Portugal Centro Hospitalar De Tras os Montes e Alto Douro, EPE | Hospital Sao Pedro - Centro de investigacao clinica Vila Real
Romania Sp. Judetean de Urgenta Dr. Constantin Opris Baia Mare Baia Mare
Romania Emergency County Hospital, Braila Braila
Romania S.C Thera Card S.R.L Brasov
Romania S.C. Centrul Medical de Diagn si Tratam Ambulator Neomed SRL Brasov
Romania Emergency Institute for Cardiovascular Diseases Bucharest
Romania Spitalul Clinic de Urgenta Sf. Ioan Bucharest
Romania Emergency Institute for Cardiovascular Diseases Bucuresti
Romania Spitalul Clinic Colentina Bucuresti
Romania Spitatul Universitar de Urgenta Bucuresti Bucuresti
Romania Niculae Stancioiu Heart Institute Cluj-Napoca Cluj Napoca
Romania Spitalul Clinic de Recuperare Cluj-Napoca Cluj Napoca
Romania CardioMed Cluj-Napoca
Romania S.C. Sal Med SRL Pitesti
Romania Spitalul Judetean de Urgenta Satu Mare Satu Mare
Romania Spitalul de urgenta Sf. Ioan Cel Nou Suceava
Romania CMI. Dr. Podoleanu Cristian Targu Mures Mures
Romania Emergency Institute of Cardiovascular Diseases & Transplant Targu Mures
Romania S.C. Cardio Med S.R.L. Targu Mures
Romania Municipal Clinical Emergency Hospital of Timisoara Timisoara Timis
Romania Timisoara Institute of Cardiovascular Diseases Timisoara
Singapore Changi General Hospital Singapore
Singapore National Heart Centre Singapore Singapore
Singapore National University Hospital Singapore
Singapore Ng Teng Fong General Hospital Singapore
Singapore Sengkang General Hospital Singapore
Singapore SingHealth Polyclinics - Pasir Ris Singapore
Singapore Tan Tock Seng Hospital Singapore
Slovakia ALIAN s.r.o. Bardejov
Slovakia GALENUM s.r.o. Bratislava
Slovakia Kardiosanus | Bratislava, Slovakia Bratislava
Slovakia Nemocnica s poliklinikou Brezno, n.o. Brezno
Slovakia KARDIO R s.r.o. Kosice
Slovakia Medical Group Kosice s.r.o. | Kosice, Slovakia Kosice
Slovakia KARDIO-ANGIO s.r.o. Levice
Slovakia KardioLEV s.r.o. Levoca
Slovakia Internal and Diabetes Clinic - IN-DIA s.r.o. | Lucenec, Slovakia Lucenec
Slovakia KARDIO 1 | Lucenec, Slovakia Lucenec
Slovakia KardioMed s.r.o. Lucenec
Slovakia ORALEK, s.r.o. Namestovo
Slovakia Kardiocentrum Nitra | Cardiology Clinic - Outpatient Department Nitra
Slovakia Specializovana nemocnica sv. Svorada Zobor, n.o. Nitra
Slovakia KaCH, s.r.o. Nove Zamky
Slovakia BENIMED s.r.o. Piestany
Slovakia Medikard | Department of Internal Medicine Presov
Slovakia MEDISPOL s.r.o. Presov
Slovakia Interna SK s.r.o. Svidnik
Slovakia Kardiologicka ambulancia Trnava, MUDr. Vladimir Macek Trnava
Slovakia Medivasa s.r.o. Zilina
Spain University Hospital of A Coruna | Cardiology department A Coruña
Spain Hospital General Universitario de Alicante Doctor Balmis | Cardiology Department Alicante
Spain Hospital de la Santa Creu i Sant Pau | Cardiology Department Barcelona
Spain Hospital Quironsalud Barcelona | Internal Medicine Department Barcelona
Spain Vall d'Hebron Barcelona Hospital Campus | Vall d'Hebron Hospital Universitario - Cardiology Department Barcelona
Spain Complejo Hospitalario Universitario de Ferrol | Hospital Naval - Unidad de Hipertensión Arterial Ferrol A Coruña
Spain Hospital Universitari de Bellvitge | Bellvitge Biomedical Research Institute - Cardiology - AF, Stroke Prevention L'Hospitalet de Llobregat Barcelona
Spain Hospital Alta Resolucion de Lebrija | Cardiology Service Department Lebrija Sevilla
Spain H. Universitario 12 de Octubre - Cardiologia Madrid
Spain Hospital Universitario de La Princesa | Internal Medicine Department Madrid
Spain Hospital Universitario La Paz | Cardiology Department - AF, Stroke Prevention Madrid
Spain Hospital Universitario La Paz | IdiPAZ - Neurology Department Madrid
Spain Hospital Universitario Ramon y Cajal | Departamento de Medicina Interna Madrid
Spain Hospital Universitario Virgen de la Victoria | Cardiology Department Malaga Málaga
Spain Hospital Clinico Universitario Virgen de la Arrixaca | Cardiology Department Murcia
Spain Hospital Universitario Central de Asturias | Servicio de Cardiologia Oviedo Asturias
Spain Jose Manuel Pascual Pascual S.A. | Hospital Virgen del Camino - Internal Medicine Department Sanlucar de Barrameda Cádiz
Spain Hospital Clinico Universitario de Santiago de Compostela | Cardiology Department Santiago de Compostela A Coruña
Spain Hospital Universitario Virgen del Rocio | Hospital General - Departmaneto de Cardiologia y Cirugia Cardiovascular Sevilla
Spain Hospital Alta Resolucion de Utrera | Cardiology Service Department Utrera Sevilla
Spain Hospital General Universitario de Valencia | Cardiology Department Valencia
Spain La Fe University and Polytechnic Hospital | Cardiology Department Valencia
Spain Jose Manuel Pascual Pascual S.A. | Hospital Virgen de las Montanas - Internal Medicine Department Villamartin Cádiz
Sweden Södra Älvsborgs Sjukhus Borås
Sweden Falu Lasarett Falun
Sweden SU/Östra Göteborg
Sweden Helsingborgs Lasarett Helsingborg
Sweden Universitetssjukhuset i Linköping Linköping
Sweden Clemenstorget Hjärtmottagning Lund
Sweden Skånes Universitetssjukhus Lund
Sweden SU/Mölndal Mölndal
Sweden Vrinnevisjukhuset Norrköping
Sweden Universitetssjukhuset Örebro Örebro
Sweden Skellefteå Lasarett Skellefteå
Sweden Danderyds sjukhus Stockholm
Sweden Karolinska Universitetssjukhuset Stockholm
Sweden Karolinska Universitetssjukhuset Huddinge Stockholm Stockholm
Sweden Södersjukhuset AB Stockholm
Sweden Norrlands Universitetssjukhus, Umea Umea
Sweden Akademiska Sjukhuset Uppsala
Sweden Västmanlands Sjukhus Västerås Västerås
Switzerland Kantonsspital Aarau Aarau Aargau
Switzerland Kantonsspital Baden Baden
Switzerland Inselspital Universitätsspital Bern Bern
Switzerland Cardiocentro Ticino Lugano
Switzerland Kantonsspital St. Gallen Saint Gallen Sankt Gallen
Switzerland UniversitätsSpital Zürich Zürich
Taiwan Changhua Christian Hospital Changhua
Taiwan Mackay Memorial Hospital - Hsinchu Branch Hsinchu
Taiwan Buddhist Tzu-Chi General Hospital, Hualien Hualien
Taiwan Chang Gung Memorial Hospital Kaohsiung Kaohsiung
Taiwan E-Da Hospital Kaohsiung
Taiwan Veterans General Hospital Kaohsiung
Taiwan Kaohsiung Medical University Chung-Ho Memorial Hospital Kaohsiung City Kaohsiung
Taiwan MacKay Memorial Hospital Tamsui Branch New Taipei City Taipei
Taiwan China Medical University Hospital Taichung
Taiwan Chung Shan Medical University Hospital Taichung
Taiwan Taichung Veterans General Hospital Taichung
Taiwan Chi Mei Medical Center Taikang Tainan
Taiwan National Cheng Kung University Hospital Tainan
Taiwan Cathay General Hospital Taipei
Taiwan Mackay Memorial Hospital Taipei
Taiwan National Taiwan University Hospital Taipei
Taiwan Taipei Medical University Hospital Taipei
Taiwan Taipei Municipal Wanfang Hospital Taipei
Taiwan Taipei Veterans General Hospital Taipei
Taiwan Shin Kong Wu Ho-Su Memorial Hospital Taipei City Taipei
Taiwan Tri-Service General Hospital Taipei City
Taiwan Chang Gung Memorial Hospital at Linkou Taoyuan
Taiwan National Yang Ming Chiao Tung University Hospital Yilan City Ilan
Turkey S.B.U. Adana Sehir Egitim ve Arastirma Hastanesi Adana
Turkey Afyonkarahisar Saglik Bilimleri Universitesi Afyonkarahisar
Turkey Baskent Universitesi Tip Fakultesi Hastanesi Ankara
Turkey Health Ministry Of Türkiye Republic Ankara Bilkent City Hospital Ankara
Turkey Akdeniz Universitesi Tip Fakultesi Hastanesi Antalya
Turkey Hitit Universitesi Tip Fakultesi Corum
Turkey Ataturk Universitesi Tip Fakultesi Erzurum
Turkey Eskisehir Osmangazi Universitesi Tip Fakultesi Eskisehir
Turkey Istanbul Mehmet Akif Ersoy Gogus Kalp Damar Cerrahisi E.A.H. Istanbul
Turkey Istanbul Universitesi Cerrahpasa - Kardiyoloji Anabilim Dali Istanbul
Turkey Marmara Uni. Tip Fak. Pendik EAH Kardiyoloji Istanbul
Turkey Dokuz Eylul Universitesi Tip Fakultesi Izmir
Turkey Izmir Ekonomi Universitesi Medikal Point Hastanesi Izmir
Turkey Erciyes Universitesi Tip Fakultesi Kayseri
Turkey Kocaeli Universitesi Tip Fakultesi Kocaeli
Turkey Kutahya Saglik Bilimleri Uni. Evliya Celebi Egitim ve Arasti Kutahya
Turkey Saglik Bilimleri Univ. Samsun EAH Kardiyoloji Departmani Samsun
United Kingdom Wansbeck General Hospital Ashington Northumberland
United Kingdom North Hampshire Hospital Basingstoke Hampshire
United Kingdom Soho Health Centre, Future Meds Birmingham West Midlands
United Kingdom Ely Bridge Medical Centre Cardiff
United Kingdom Countess of Chester Hospital Chester Cheshire
United Kingdom Chesterfield Royal Hospital Chesterfield Derbyshire
United Kingdom St Richard's Hospital Chichester West Sussex
United Kingdom Craigavon Area Hospital Craigavon North Ireland
United Kingdom Russells Hall Hospital Dudley West Midlands
United Kingdom Staploe Medical Centre Ely Cambridgeshire
United Kingdom Glasgow Royal Infirmary | Stroke Unit Glasgow Glasgow City
United Kingdom Northwick Park Hospital Harrow London
United Kingdom University Hospitals Leicester Leicester Leicestershire
United Kingdom Heart and Chest Hospital Liverpool
United Kingdom Charing Cross Hospital London
United Kingdom King's College Hospital - NHS Foundation Trust London
United Kingdom Queen Elizabeth the Queen Mother Hospital Margate Kent
United Kingdom James Cook University Hospital South Tees Middlesborough North Yorkshire
United Kingdom Freeman Hospital Newcastle Tyne And Wear
United Kingdom Poole Hospital NHS Trust Poole Dorset
United Kingdom Lister Hospital Stevenage Hertfordshire
United Kingdom Torbay Hospital Torbay Devon
United Kingdom Future Meds - Bromborough Wirral
United Kingdom Worcestershire Acute Hospital Trust Worcester Worcestershire
United States Cambridge Medical Trials Alexandria Louisiana
United States PharmaTex Research, LLC Amarillo Texas
United States Accellacare-Ames Ames Iowa
United States AnMed Clinical Research Anderson South Carolina
United States Grady Memorial Hospital Atlanta Georgia
United States Johns Hopkins Hospital/Health System Baltimore Maryland
United States LifeBridge Health | Sinai Hospital | Platelet and Thrombosis Research Department Baltimore Maryland
United States St. Agnes Hospital Baltimore Maryland
United States Northeast Cardiology Associates Bangor Maine
United States Ochsner Clinic Foundation Baton Rouge Louisiana
United States McLaren Bay Region Medical Center Bay City Michigan
United States Florida Premier Cardiology Boynton Beach Florida
United States Integrity Clinical Research | Cardiology Associates of South Florida Boynton Beach Florida
United States Cardiovascular and Vein Center of Florida Bradenton Florida
United States Nova Clinical Research | Brandenton, FL Bradenton Florida
United States Advanced Heart Care, LLC | Bridgewater, NJ Bridgewater New Jersey
United States Holston Medical Group - Bristol Bristol Tennessee
United States Cooper Specialty Care at Voorhees Camden New Jersey
United States Capital Area Research, LLC Camp Hill Pennsylvania
United States Aultman | Aultman Hospital Main Campus - Clinical Trials Canton Ohio
United States University of North Carolina Chapel Hill North Carolina
United States Erlanger Health, Inc. Chattanooga Tennessee
United States Clearwater Cardiovascular Associates | Clearwater, FL Clearwater Florida
United States Johns Hopkins University Columbia Maryland
United States Life Spring Research Coral Gables Florida
United States Valley Clinical Trials, Inc. | Covina, CA Covina California
United States Cardiovascular Associates Research, LLC Covington Louisiana
United States Science 37 Culver City California
United States NSC Research INC Cumming Georgia
United States Southwest Family Medicine Associates Dallas Texas
United States Cardiology Associates Research Company Daytona Beach Florida
United States Cardiology Consultants, PA Daytona Beach Florida
United States Heller Heart Health Delray Beach Florida
United States Prime Revival Reserach Institute, LLC | Denton, TX Denton Texas
United States Henry Ford Health System Detroit Michigan
United States SEC Clinical Research Dothan Alabama
United States Doylestown Hospital Doylestown Pennsylvania
United States Alta Pharmaceutical Research Center, LLC Dunwoody Georgia
United States Duke Univ. Medical Center Durham North Carolina
United States Duke University School of Medicine Durham North Carolina
United States David Turbay MD PLLC El Paso Texas
United States Midwest Cardiovascular Research and Education Foundation Elkhart Indiana
United States Inova Fairfax Hospital - Fairfax Fairfax Virginia
United States Eastern Shore Research Institute, LLC | Fairhope, AL Fairhope Alabama
United States Virginia Heart Falls Church Virginia
United States Lillestol Research, LLC Fargo North Dakota
United States Aa Mrc, Llc Flint Michigan
United States Piedmont Research Partners LLC Fort Mill South Carolina
United States Anderson Medical Research LLC Fort Washington Maryland
United States Texas Health Physicians Group - Fort Worth Fort Worth Texas
United States Texas Health Research & Education Institute Fort Worth Texas
United States Malcom Randall VA Medical Ctr Gainesville Florida
United States Stern Cardiovascular Center Germantown Tennessee
United States Northshore Medical Center Glenview Illinois
United States Nebraska Heart Institute- Grand Island Grand Island Nebraska
United States Medication Management, LLC Greensboro North Carolina
United States Cardiology Associates of Northwest Indiana, PC Hammond Indiana
United States Pennsylvania State University College of Medicine Hershey Pennsylvania
United States Indago Research & Health Center, Inc. Hialeah Florida
United States Houston Methodist Hospital Houston Texas
United States IU Health Physicians Cardiology Indianapolis Indiana
United States Nature Coast Clinical Research, LLC Inverness Florida
United States Apex Cardiology, LLC Jackson Tennessee
United States Jackson Heart Clinic | Jackson, MS Jackson Mississippi
United States University of Florida - Jacksonville Jacksonville Florida
United States Kettering Health Network | Research Institute Kettering Ohio
United States TCR Institute Kingwood Texas
United States Accellacare | Mt. Pleasant, South Carolina Ladson South Carolina
United States Sparrow Clinical Research Institute | Sparrow Hospital - Clinical Research Department Lansing Michigan
United States Baptist Health Lexington Lexington Kentucky
United States NJ Medcare/NJ Heart Linden New Jersey
United States Arkansas Cardiology - Little Rock Little Rock Arkansas
United States South Denver Cardiology Associates, PC Littleton Colorado
United States VA Long Beach Healthcare System Long Beach California
United States Heart Vein & Vascular | Longwood, FL Longwood Florida
United States VA Greater Los Angeles Healthcare System Los Angeles California
United States Baptist Health Medical Group - Louisville Cardiology Louisville Kentucky
United States Garden State Heart Care Manalapan New Jersey
United States Carient Heart and Vascular Manassas Virginia
United States M Health Fairview Maplewood Minnesota
United States Rama Research LLC | Marion, OH Marion Ohio
United States North Dallas Research Associate | McKinney, TX McKinney Texas
United States North Texas Research Associates McKinney Texas
United States St. Luke's Health System | St. Luke's Clinic - Idaho Cardiology Associates Meridian Idaho
United States Circuit Clinical/Crystal Run Middletown New York
United States Minneapolis VA Medical Center Minneapolis Minnesota
United States Mobile Heart Specialists, PC Mobile Alabama
United States Clinical Trials of America, Inc. Mount Airy North Carolina
United States Inspira Medical Centers | Clinical Research Office Mullica Hill New Jersey
United States Advanced Research for Health Improvement Naples Florida
United States Southwest Florida Research | Naples, FL Naples Florida
United States Vanderbilt University Medical Center Nashville Tennessee
United States Ochsner Medical Center - New Orleans New Orleans Louisiana
United States NYU Langone Health | NYU Langone Medical Associates Chelsea - Cardiovascular Research New York New York
United States Radin Cardiovascular Medical Group, Inc. Newport Beach California
United States York Clinical Research Norfolk Virginia
United States Amicis Research Center | Northridge, CA Northridge California
United States Cardiology Associates of Fairfield County, P.C. | Stamford, CT Norwalk Connecticut
United States Affinity Health Research Institute | Oak Brook, IL Oak Brook Illinois
United States South Oklahoma Heart Research, LLC Oklahoma City Oklahoma
United States Research Integrity, LLC Owensboro Kentucky
United States Cardiology Partners Clinical Research Institute Palm Beach Gardens Florida
United States Baptist Heart and Vascular/Cardiology Consultants Pensacola Florida
United States Thomas Jefferson University Hospitals Philadelphia Pennsylvania
United States Styde Research LLC | Plano, TX Plano Texas
United States Peace River Cardiovascular Center | Port Charlotte, FL Port Charlotte Florida
United States Sound Medical Research Port Orchard Washington
* Note: There are 1037 locations in all - only the first 1000 are shown.

Sponsors (1)

Lead Sponsor Collaborator
Bayer

Countries where clinical trial is conducted

United States,  Argentina,  Australia,  Austria,  Belgium,  Brazil,  Bulgaria,  Canada,  China,  Czechia,  Denmark,  Estonia,  Finland,  France,  Germany,  Greece,  Hungary,  India,  Israel,  Italy,  Japan,  Korea, Republic of,  Latvia,  Lithuania,  Malaysia,  Netherlands,  Norway,  Poland,  Portugal,  Romania,  Singapore,  Slovakia,  Spain,  Sweden,  Switzerland,  Taiwan,  Turkey,  United Kingdom, 

Outcome

Type Measure Description Time frame Safety issue
Primary Time to first occurrence of composite of stroke or systemic embolism Up to 34 months
Primary Time to first occurrence of ISTH major bleeding ISTH = International Society on Thrombosis and Hemostasis Up to 34 months
Primary Time to first occurrence of composite of stroke, systemic embolism, or ISTH major bleeding Up to 34 months
Secondary Time to first occurrence of composite of ischemic stroke or systemic embolism Up to 34 months
Secondary Time to first occurrence of all-cause mortality Up to 34 months
Secondary Time to first occurrence of ischemic stroke Up to 34 months
Secondary Time to first occurrence of CV death CV = cardiovascular Up to 34 months
Secondary Time to first occurrence of composite of CV death, stroke, or myocardial infarction Up to 34 months
Secondary Time to first occurrence of composite of ISTH major or clinically relevant non-major bleeding Up to 34 months
Secondary Time to first occurrence of clinically relevant non-major bleeding Up to 34 months
Secondary Time to first occurrence of hemorrhagic stroke Up to 34 months
Secondary Time to first occurrence of intracranial hemorrhage Up to 34 months
Secondary Time to first occurrence of fatal bleeding Up to 34 months
Secondary Time to first occurrence of minor bleeding Up to 34 months
Secondary Time to first occurrence of composite of stroke, systemic embolism, ISTH major bleeding, or all-cause mortality Up to 34 months
Secondary Time to first occurrence of composite of disabling stroke (mRS = 3), critical bleeding, or all-cause mortality mRS = modified Rankin Scale Up to 34 months
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