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Atrial Fibrillation clinical trials

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NCT ID: NCT01530750 Recruiting - Atrial Fibrillation Clinical Trials

READ-POAF Pilot Studies Postoperative Atrial Fibrillation After Cardiac Surgery

Start date: March 2012
Phase: N/A
Study type: Observational

Postoperative atrial fibrillation after coronary artery bypass grafting will be monitored up to 1 year after the procedure by implanting a Reveal XT internal loop recorder two weeks before the surgery. Frequency, burden, and possible risk factors will be described. During the operation direct contact epicardial mapping will be performed and tissue samples will be collected to identify an electrophysiological and a structural substrate for development of AF.

NCT ID: NCT01502176 Recruiting - Complications Clinical Trials

A Retrospective Register Study to Map the Frequency of Short Duration Atrial Fibrillation (AF) Among All Patients Admitted to Roskilde Sygehus in Denmark in 2010

Start date: December 2011
Phase: N/A
Study type: Observational

Retrospective observational study of patients with atrial fibrillation admitted to Roskilde University Hospital in 2010.

NCT ID: NCT01444573 Recruiting - Atrial Fibrillation Clinical Trials

Rate Ventricular Control Therapy in Patients With Permanent Atrial Fibrillation

REVEAL
Start date: September 2011
Phase: Phase 3
Study type: Interventional

The investigators hypothesized that very lenient rate control is not inferior to strict or lenient rate control assessed by implantable continuous ECG monitor for preventing cardiovascular hospitalization and mortality in patients with long-standing persistent or permanent atrial fibrillation

NCT ID: NCT01363193 Recruiting - Obesity Clinical Trials

Safety and Efficacy of Lean Body Weight-based IV Heparin Dosing in Obese/Morbidly Obese Patients

Start date: July 2011
Phase: N/A
Study type: Interventional

Standard weight-based IV heparin for normal weight patients is based on actual body weight (ABW). However, no well-defined guidelines have been established for patients considered to be obese or morbidly obese. In current practice, the calculated ABW based heparin initial bolus dose and infusion rates are quite high, and therefore often not used for obese/morbidly obese patients for fear of bleeding. Heparin is distributed in the body approximately the same as blood and does not get distributed to adipose tissue. There are some studies suggesting that lean body weight (LBW) might be a better basis for dosing heparin. LBW is a calculated weight that excludes the weight of fat. The investigators hypothesize that intravenous heparin dosing based on the Lean body weight of obese/morbidly obese patients would be safe and effective in achieving a therapeutic level of heparin in 24 hours compared to the usual practice in this patient population.

NCT ID: NCT01352416 Recruiting - Clinical trials for Heart; Dysfunction Postoperative, Cardiac Surgery

Suppression Of Atrial Fibrillation With Ranolazine After Cardiac Surgery

Start date: September 2010
Phase: N/A
Study type: Interventional

The objective of this study is to show that ranolazine is a safe, viable and potent alternative for post-operative atrial fibrillation suppression in patients undergoing cardiac surgery

NCT ID: NCT01349491 Recruiting - Atrial Fibrillation Clinical Trials

Ranolazine for the Prevention of Atrial Fibrillation After Electrical Cardioversion

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The investigators hypothesize that ranolazine would decrease the incidence of recurrence of Atrial Fibrillation (AF) after electrical cardioversion of persistent AF. Patients with persistent AF who are candidates for electrical cardioversion will be randomized to either placebo or ranolazine after successful electrical cardioversion.

NCT ID: NCT01341353 Recruiting - Atrial Fibrillation Clinical Trials

Catheter Ablation Versus Antiarrythmic Drugs for Atrial Fibrillation in China

Start date: April 2011
Phase: Phase 4
Study type: Interventional

The mainstay of treatment for atrial fibrillation remains pharmacological;however,catheter ablation has increasingly been used over the last decades. The relative merits of each strategy have not been extensively studied. Our study was designed to determine if catheter ablation is a feasible option as first-line therapy for treating patients with symptomatic AF.

NCT ID: NCT01339611 Recruiting - Atrial Fibrillation Clinical Trials

Education Program for Patients Receiving Oral Anticoagulation

Start date: May 2011
Phase: N/A
Study type: Interventional

The aim of the study is to test if patients under oral anticoagulation therapy who are going to participate in the education program will have better Health-related quality of life, higher rate in pharmacological treatment adherence and better self efficacy to manage the treatment.

NCT ID: NCT01265758 Recruiting - Atrial Fibrillation Clinical Trials

Telemetric Arrhythmia Diagnosis in Adults

TELEMARC1
Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to assess efficacy of prolonged Full Disclosure electrocardiogram (ECG) monitoring and signal analysis using advanced telemetric technology in comparison with a standard Holter ECG recording and an Event Holter recording to diagnose cardiac arrhythmia.

NCT ID: NCT01265303 Recruiting - Atrial Fibrillation Clinical Trials

Telemetric Arrhythmia and Syncope Diagnosis - Evaluation of Arrhythmia Treatment Efficacy

TELEMARC 4
Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to assess efficacy of prolonged Full Disclosure ECG monitoring and signal analysis using advanced GSM telemetric technology to prescribe the most appropriate treatment of arrhythmia.