Asthma Clinical Trial
Official title:
Assessing the Prevalence of Respiratory Impairment in Chronic Inflammatory Bowel Diseases
Patients will be recruited during a routine consultation with a physician in the
hepato-gastroenterology department.
At the end of the consultation, patients will have to complete the following questionnaire:
"European Community Respiratory Health Survey" which allows the screening of patients at risk
of chronic respiratory diseases (asthma, COPD, bronchiectasis, emphysema).
In the event of a declaration of functional respiratory signs, a consultation with a
pulmonologist will be systematically proposed. At the end of this consultation, if the doctor
deems it necessary, further investigations will be proposed and/or regular follow-up
organised.
The main objective of this study is to estimate the prevalence of respiratory symptoms
leading to a diagnosis of chronic respiratory disease in patients with inflammatory bowel
diseases (IBD) (Crohn's disease and UC).
The main criterion for judgement will be the frequency of functional respiratory signs
(wheezing, dyspnea, cough, sputum) reported by IBD patients through an adapted self-report
questionnaire.
Approximately one-third of IBD patients will develop systemic extra-digestive manifestations
(joint, dermatologic or ophthalmologic) during the course of their disease and up to 25% will
develop these systemic manifestations even before the diagnosis of IBD. Among these systemic
affections, respiratory manifestations remain poorly known because they are not searched for
in daily clinical practice.
The main objective of this study is to estimate the prevalence of respiratory symptoms
leading to a diagnosis of chronic respiratory disease (asthma, COPD, bronchiectasis) in
patients with IBD (Crohn's disease and UC).
Patients will be recruited during a routine consultation with a physician in the
hepato-gastroenterology department as part of the management of their chronic inflammatory
bowel disease.
During this consultation, the investigating physician will explain to the patient the
objective of the study and check with him/her the eligibility criteria. The patient will then
be given an information note. He or she may ask any questions he or she wishes and if he or
she refuses to participate in the study, he or she will have to sign an objection form in
duplicate (one copy will be given to the patient and the other will be kept in the medical
file). The doctor will also sign these two copies.
At the end of the consultation, patients will have to complete the following questionnaire:
"European Community Respiratory Health Survey" which allows the screening of patients at risk
of chronic respiratory diseases (asthma, COPD, bronchiectasis, emphysema).
In the event of a declaration of functional respiratory signs, a consultation with a
pulmonologist from the Department of Pulmonology of the CHRU Nancy-Brabois will be
systematically proposed. At the end of this consultation, if the doctor deems it necessary,
further investigations will be proposed and/or regular follow-up organised. Patients will be
informed of this potential follow-up in pneumology before the questionnaire is given. There
is no change in the usual follow-up of the population in case of non-reporting of functional
respiratory signs.
The main criterion for judgement will be the frequency of functional respiratory signs
(wheezing, dyspnea, cough, sputum) reported by IBD patients through an adapted self-report
questionnaire.
If our hypothesis is confirmed, this will have direct practical consequences on the global
and multidisciplinary management of IBD patients, in particular through a systematic search
for chronic respiratory disease, which is currently under-researched in these patients.
This will improve the quality of life as well as the morbidity and mortality of our patients.
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