Blood Collection From Individuals With Lung Disease for Genetic Studies

Asthma Clinical Trial

Official title:

Collection of Blood for Gene Expression/Genomic Studies in Individuals With Chronic Lung Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00362739
• Other study ID #: 0508008095
• Status: Completed
• Phase: N/A
• First received: August 8, 2006
• Last updated: April 28, 2016
• Start date: September 2005
• Est. completion date: August 2015

Study information

• Verified date: April 2016
• Source: Weill Medical College of Cornell University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This is a research study where researchers are collecting blood to evaluate the genetic characteristics of individuals with chronic lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, cystic fibrosis, and lung cancer.

Description:

The investigators hope to be able to identify an association between a genetic make-up in the blood samples and the risks of developing a particular lung disease, or severity of a lung disease. The findings of this study might be important to develop future preventative methods and potential treatments for the management of lung disease. The investigators aim to collect blood samples from 300 people with lung disease and 300 controls over 5 years.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 3087
• Est. completion date: August 2015
• Est. primary completion date: August 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Must provide informed consent

• Males and females, age 18 years and older

• Lung disease proven by at least one of the following:

• symptoms consistent with pulmonary disease

• chest X-rays consistent with lung disease

• pulmonary function tests consistent with lung disease

• lung biopsy consistent with lung disease

• family history of lung disease

• disease of organs with know associated with lung disease

• individuals suspected of history of lung disease based on history and/or physical examination

• normal controls (individuals without history of lung disease) to be sampled to provide a comparison to the lung disease cohort.

Exclusion Criteria:

• Drug and/or alcohol abuse within the past six months

• Females who are pregnant or nursing

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Asthma
• COPD
• Cystic Fibrosis
• Interstitial Lung Disease
• Lung Cancer
• Lung Diseases
• Lung Diseases, Interstitial

Locations

Country	Name	City	State
United States	New York Presbyterian Hospital -- Weill Cornell Medical College of Cornell University	New York	New York

Sponsors (1)

Lead Sponsor	Collaborator
Weill Medical College of Cornell University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Establish a set of normal ranges for various parameters in healthy individual specimens and compare to specimens from individuals with lung disease to determine parameters resulting in disease susceptibility and severity.		5 years	No