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NCT04963023 Clinical Trial

Biomarkers of Chronic Obstructive Pulmonary Disease

Asthma Clinical Trial

— BIOBPCO  

Official title:
Specific Biomarker Identification of Different Subgroups of Chronic Obstructive Pulmonary Disease

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04963023
Other study ID # PI2021_843_0051
Secondary ID
Status Completed
Phase
First received
Last updated
Start date June 15, 2021
Est. completion date July 1, 2023

Study information
Verified date August 2023
Source Centre Hospitalier Universitaire, Amiens
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.

Recruitment information / eligibility
Status Completed
Enrollment 75
Est. completion date July 1, 2023
Est. primary completion date July 1, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - BPCO patients - ACOS patients - asthmatic patient without BPCO Exclusion Criteria: - infection - exacerbation - immunosuppressive treatment - immunosuppressive disease

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Physical examinations
BPCO physical examinations
Diagnostic Test:
• blood test
blood test in order to study immunologic markers

Locations
Country Name City State
France CHU Amiens Amiens

Sponsors (1)
Lead Sponsor Collaborator
Centre Hospitalier Universitaire, Amiens

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary identification specific blood immunologic marker for COPD COPD biomarkers are blood immunologic markers one hour
Secondary Complete blood count (CBC) Variation between COPD and asthmatic patients one hour
Secondary c-reactive protein concentration variation between COPD and asthmatic patients one hour
Secondary Plasma protein electrophoresis profile Variation between COPD and asthmatic patients one hour
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