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Asthma clinical trials

View clinical trials related to Asthma.

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NCT ID: NCT00117338 Completed - Asthma Clinical Trials

A Study of an Intravenous Drug in Pediatric Patients With Acute Asthma (0476-301)

Start date: July 2005
Phase: Phase 3
Study type: Interventional

This study will attempt to find out if the addition of an intravenous form of a drug that is already used for treating asthma in children will help resolve asthma attacks faster than using the current standard care alone.

NCT ID: NCT00116324 Completed - Asthma Clinical Trials

Predicting the Response to Montelukast by Genetic Variation in Asthmatics

Start date: April 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine a specific variation in the genetic code for an enzyme (LTC4 synthase) which plays an important role in the airway inflammation associated with asthma. We hypothesize that asthmatic patients with this variant gene will have a better response to montelukast than patients with the wild type gene, as measured by the ability of montelukast to protect against a hypertonic saline challenge.

NCT ID: NCT00116311 Active, not recruiting - Healthy Clinical Trials

Effects of Allergen Inhalation on Adenosine Receptor Expression in Sputum and Peripheral Blood

Start date: July 2005
Phase: N/A
Study type: Observational

The purpose of this study is to determine whether asthmatics have different adenosine receptor expression profiles than healthy controls. We hypothesize that asthmatics will have increased adenosine receptor expression versus control subjects. We also want to study the effects of allergen inhalation on adenosine receptor expression in asthmatics. We believe that adenosine receptor expression will be upregulated after allergen inhalation. Both hypotheses are being tested in sputum and peripheral blood.

NCT ID: NCT00116103 Completed - Asthma Clinical Trials

A Study of the Safety and Efficacy of Tacrolimus Inhalation Aerosol in Subjects With Persistent Asthma

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of tacrolimus inhalation aerosol in subjects with persistent asthma.

NCT ID: NCT00115323 Completed - Asthma Clinical Trials

Comparison of Two Medication Adherence Strategies to Improve Asthma Treatment Adherence

Start date: May 2005
Phase: N/A
Study type: Interventional

This is a randomized, controlled study that will compare two medication adherence strategies in adults with moderate or severe persistent asthma as a method for improving or maintaining treatment adherence.

NCT ID: NCT00115297 Active, not recruiting - Asthma Clinical Trials

Montelukast for Early Life Wheezing

Start date: September 2004
Phase: Phase 2/Phase 3
Study type: Interventional

This study will determine the effects of montelukast on the duration of wheezing in children 12 months to 3 years of age who visit a physician for care of a wheezing illness. Only patients from the Ankara area of Hacettepe University Medical Center in Turkey will be included in this study.

NCT ID: NCT00115284 Completed - Asthma Clinical Trials

Changes in Physician Performance Through Continuous Professional Development

Start date: January 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether having physicians evaluate their management of certain diseases as part of board recertification results in improved patient care.

NCT ID: NCT00114881 Active, not recruiting - Asthma Clinical Trials

Urban Environmental Factors and Childhood Asthma

URECA
Start date: February 2, 2005
Phase:
Study type: Observational

Minority children who grow up in poor urban neighborhoods have the highest rates of asthma, and also experience greater morbidity from acute exacerbations of this disease. The aim of this study is to further identify environmental factors unique to the inner city that affect immune development and the expression of wheezing, atopy and asthma for purposes of identifying new strategies for asthma prevention.

NCT ID: NCT00114413 Completed - Asthma Clinical Trials

Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents

Start date: August 2004
Phase: N/A
Study type: Interventional

The purpose of ICAC-01 is to determine whether an asthma treatment strategy that measures exhaled nitric oxide (eNO) to indicate disease progression is more effective in treating asthma symptoms when combined with existing asthma treatment guidelines than treatment using the guidelines alone.

NCT ID: NCT00113659 Completed - Asthma Clinical Trials

Use of a Probiotic Supplement to Prevent Asthma in Infants

Start date: June 2005
Phase: N/A
Study type: Interventional

The goal of the study is to understand the mechanisms of how antigen presentation affects the developing immune system and subsequently affects susceptibility to, or protects against, asthma development. This randomized controlled study will test the effectiveness of daily supplementation of Lactobacillus GG for the first 6 months of life on the early immunological development of asthma.