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Asthma clinical trials

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NCT ID: NCT01113138 Completed - Asthma Clinical Trials

Study of the Metabolism of Two Magnesium Supplements in Healthy Volunteers

Start date: December 2012
Phase: N/A
Study type: Interventional

The present study is part of a project titled 'Magnesium in asthma and chronic obstructive pulmonary disease'. The hypothesis of the main project is that daily magnesium supplement will benefit patients with asthma and chronic obstructive pulmonary disease. The aim of this part of the project is to study the pharmacokinetics of the following two magnesium supplements: - Mablet (dietary supplement) - Magnesium Sulfate (solution for infusion)

NCT ID: NCT01113034 Completed - Asthma Clinical Trials

A Safety Trial of DAS181 (Fludase®) in Adult Subjects With Well-Controlled Asthma or Bronchiectasis

DAS181
Start date: July 2010
Phase: Phase 1
Study type: Interventional

The primary objective is to evaluate whether DAS181 is safe in subjects with well-controlled asthma or bronchiectasis.

NCT ID: NCT01111110 Completed - Asthma Clinical Trials

Response to Albuterol Delivered Through an Anti-static Valved Holding Chamber During Nocturnal Bronchospasm

Start date: May 2008
Phase: N/A
Study type: Interventional

Delivery of HFA albuterol through an antistatic valved holding chamber (VHC) will improve bronchodilator response during nocturnal bronchospasm.

NCT ID: NCT01110460 Completed - Asthma Clinical Trials

Prospective Study on Asthma Control

PRISMA
Start date: January 2009
Phase: N/A
Study type: Observational

Accordingly, the new update of the Global Initiative for Asthma (GINA) guidelines 2006 is based on the control of the disease and attempts to quantify and graduate the level of control by using a classification of asthmatic subjects into controlled,partly controlled and uncontrolled groups. Achieving and maintaining optimal asthma control is a major goal of asthma management. Although the results of clinical trials advocate that asthma control can be reached in most patients, there is evidence that many subjects with asthma have poorly controlled disease and that there is a significant gap between the treatment goals and the current level of asthma control achieved in the general population. The aim of this study is to assess the prevalence of uncontrolled and partly controlled asthma in Italy using a patient-based tool such as Asthma Control Test.

NCT ID: NCT01109745 Completed - Asthma Clinical Trials

Effectiveness of the Pelican Instrument in Medical Care

PELICANII
Start date: August 2011
Phase: N/A
Study type: Interventional

The objective of this project is to establish the effectiveness of implementation of a self-administered electronic asthma-specific quality of life instrument for childhood asthma in primary care and specialist care.

NCT ID: NCT01106326 Completed - Asthma Clinical Trials

A Pilot Study to Improve Preventive Asthma Care for Urban Adolescents

Start date: September 2009
Phase: N/A
Study type: Interventional

The goal of this pilot study is to implement directly observed therapy with preventive asthma medications through a partnership with the school nurse (with input and direction from the primary care provider) to assure that the teen receives guideline based preventive medications, and provide a motivational interviewing intervention to help the teen transition to independence with their medical treatment plan. We hypothesize that this community-based pilot intervention will; 1) be feasible and acceptable among this population and among school personnel, and 2) yield reduced asthma morbidity (symptom-free days, absenteeism, and emergency room / urgent care use for asthma care). We anticipate that enhancing preventive healthcare for urban teens with asthma through partnerships with schools will yield improved health, prevention of suffering, decreased absenteeism from school, and reduced healthcare costs. This new method of preventive care delivery could be sustained within the school nursing system, and could be implemented in schools nationwide. Further, it could be applied to other chronic illnesses affecting disadvantaged populations.

NCT ID: NCT01105923 Active, not recruiting - Breast Cancer Clinical Trials

Study of an Intervention to Improve Problem List Accuracy and Use

MAPLE
Start date: May 2010
Phase: N/A
Study type: Interventional

The aim of this study is to identify patients with problem list gaps and intervene to correct these gaps by creating clinical decision support interventions that alert providers to likely problem list gaps and offer clinicians the opportunity to correct them. The investigators will randomize the clinics that will receive the intervention and formally evaluate the study after a period of 6 months for improved problem list completeness to determine the effectiveness of our intervention.

NCT ID: NCT01105754 Completed - Asthma Clinical Trials

A Multifaceted Prompting Intervention for Urban Children With Asthma

PAIR-UP
Start date: October 2008
Phase: N/A
Study type: Interventional

The overall goal of this project is to evaluate whether a multifaceted prompting intervention, administered in the urban primary care office setting, reduces morbidity among urban children with asthma. This study builds on our experience with a pilot study in two urban continuity clinics, in which we found that prompting clinicians about asthma severity and care guidelines at the time of an office visit resulted in improved preventive care delivery to inner-city children. This type of prompting program has the potential to substantially improve care for impoverished children with asthma, and we propose to establish: 1) whether these findings can be replicated in a similar study including a larger sample of urban children from different types of practices, and 2) whether the positive effects can be enhanced by more specific prompting directed towards both the provider and the caregiver and by providing practice-level supports and feedback. We hypothesize that children receiving a multifaceted prompting intervention (MPI) will experience less asthma-related morbidity (defined by symptom-free days at the 2-month follow-up) compared to children receiving usual care. Our secondary hypothesis is that children receiving the MPI will receive improved preventive asthma care (defined by guideline-based corrective actions taken at the index visit) compared to children receiving usual care.

NCT ID: NCT01104012 Completed - Rhinitis, Allergic Clinical Trials

Validation of Proteomic Analyses for Allergic Asthma and Rhinitis

VAPARA
Start date: May 2010
Phase: N/A
Study type: Observational

The purpose of this study is to verify and validate the intrinsic diagnostic value in terms of sensitivity and specificity of proteomic profiles determined during a pre-study for discriminating between allergy related asthma and allergy related rhinitis.

NCT ID: NCT01103349 Completed - Asthma Clinical Trials

BI 671800 in Asthmatic Patients on Inhaled Corticosteroids

Start date: April 20, 2010
Phase: Phase 2
Study type: Interventional

This is a 6 week study to assess the effect of BI 671800 in patients with asthma. It is a double blind, parallel arm trial testing the safety and efficacy of BI 671800. The main objective is to assess the effect on lung function. The study will also provide data on the pharmacokinetics of BI 671800.