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Asthma clinical trials

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NCT ID: NCT00635882 Completed - Asthma Clinical Trials

Asthma Study Comparing Anti-Inflammatory Effects of 3 Doses of Mometasone Furoate/Formoterol Fumarate and Medium Dose Mometasone Furoate (Study P05122 AM1)(COMPLETED)

Start date: February 2008
Phase: Phase 2
Study type: Interventional

This is a 2-week double-blind, placebo-controlled, parallel group study comparing the anti-inflammatory effects of low, medium, and high dose mometasone furoate/formoterol fumarate (MF/F) metered dose inhaler (MDI) formulation and medium dose mometasone furoate (MF) dry powder inhaler (DPI) and MDI formulations in adults and adolescents with persistent allergic asthma.

NCT ID: NCT00634608 Completed - Obesity Clinical Trials

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

Start date: February 2008
Phase: N/A
Study type: Interventional

The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow. Hypothesis 1: Individuals in the intervention group who receive tailored email health information with provider selected MedlinePlus links and added commentary for patient specific conditions will be more likely to seek information / use MedlinePlus compared with individuals in the control group. Hypothesis 2: Individuals in the intervention group who receive tailored email health information with provider selected MedlinePlus links and added commentary for patient specific conditions will be more satisfied with the information received compared with individuals in the control group.

NCT ID: NCT00634036 Completed - Asthma Clinical Trials

Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics

GLITZ Asthma
Start date: October 2009
Phase: Phase 2
Study type: Interventional

Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics. Researchers believe this occurs because excess adipose tissue (fat) in the body can cause higher-than-normal levels of leptin and lower-than-normal levels of adiponectin in the blood. The researchers of this study are testing a medication called pioglitazone in overweight asthmatics because they believe it can help regulate leptin and adiponectin and that this may improve symptoms of asthma.

NCT ID: NCT00632502 Completed - Neutrophilic Asthma Clinical Trials

Neutrophilic Asthma Study With Navarixin (MK-7123, SCH 527123) (MK-7123-017)(COMPLETED)

Start date: May 1, 2008
Phase: Phase 2
Study type: Interventional

4-Week Safety Study in Subjects with Neutrophilic Asthma

NCT ID: NCT00629785 Completed - Obesity Clinical Trials

The Analysis of BMI, Asthma Prevalence, and Lung Functions of Schoolchildren in Southern Taiwan

Start date: n/a
Phase: N/A
Study type: Observational

The prevalence of obesity and asthma has increased in recent decades. We investigated the relationship between body mass index (BMI) and lung function, and also tried to determine if asthma prevalence differs between obese and non-obese children. We propose this cross-sectional, retrospective analysis to figure out whether the BMI is associated with elevated prevalence of asthma, and how their lung function changes in different BMI groups.

NCT ID: NCT00628953 Completed - Asthma Clinical Trials

Adult Asthmatics and Acid Reflux

Start date: October 2002
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Nexium in the treatment of subjects with persistent asthma believed to have acid reflux as a contributory factor to control of their asthma.

NCT ID: NCT00628758 Completed - Asthma Clinical Trials

A Comparison of Symbicort® Single Inhaler Therapy and Conventional Best Practice for the Treatment of Persistent Asthma

PASSION
Start date: December 2005
Phase: Phase 3
Study type: Interventional

The primary objective is to compare the efficacy of Symbicort Single inhaler Therapy with treatment according to conventional best practice in adult patients with persistent asthma.

NCT ID: NCT00628563 Completed - Asthma Clinical Trials

REALL: A Retrospective Observational Study to Compare the Effectiveness and Cost-Effectiveness Between Different Step-3 Asthma Treatment Strategies

REALL
Start date: September 2007
Phase: N/A
Study type: Observational

This is a retrospective observational study utilising anonymised individual patient clinical and prescribing information routinely collected by UK General Practitioners (GPs). This information will be observed for two years, one year pre and one year post- "Index Prescription Date" (IPD). The IPD is the date when a patient was first switched to any option of the step-3 asthma treatment regimen. The one year before the IPD is the baseline period and will be reviewed for risk factors and confounding factors. The one year after the IPD is the outcome period and will be observed to see the outcomes of the new treatment.

NCT ID: NCT00627731 Completed - Asthma Clinical Trials

Oral Glucocorticosteroid in the Treatment of Severe Asthma Exacerbation in Hospitalized Patients

Start date: June 2007
Phase: Phase 4
Study type: Interventional

A comparison of oral prednisolone administration with intravenous methylprednisolone infusion in the treatment of acute asthma exacerbation in hospitalized patients. Oral glucocorticosteroids administration may be effective as intravenous high-dose methylprednisolone infusion.

NCT ID: NCT00627679 Completed - Asthma Clinical Trials

Safety and Blood Level Study of Unit Dose Budesonide

UDB P101
Start date: December 2005
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the tolerability and pharmacokinetics of three doses of MAP0010 (Unit Dose Budesonide) compared with Pulmicort Respules® (Budesonide) in healthy volunteers.