Early Antibiotics After Aspiration in ICU Patients

Status Recruiting

Clinical Trial Summary

The purpose of this study is to evaluate the use of early antibiotics in ICU patients who appear to have aspirated, to help determine whether this improves outcomes by reducing the later incidence of pneumonia and other negative consequences.

Clinical Trial Description

ICU patients with signs of aspiration on imaging and a clinical history supportive of aspiration, but with no clear signs of infectious pneumonia, will be randomized to receive either 5 days of empiric antibiotics or supportive care only. They will be followed for 30 days with a primary outcome of ICU length-of-stay and various secondary outcomes including mortality, ventilator days, and antibiotic days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05079620
Study type	Interventional
Source	UConn Health
Contact	Brandon Oto, PA-C
Phone	860-679-3107
Email	oto@uchc.edu
Status	Recruiting
Phase	Phase 4
Start date	November 30, 2021
Completion date	December 30, 2024

View Details

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