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NCT ID: NCT04546412 Completed - ART Clinical Trials

Importance of the Microtubule Cytoskeleton in Oocyte Competence

Start date: October 9, 2020
Phase:
Study type: Observational

This study will assess if there are microtubule cytoplasmic features specifically associated with oocyte vitrification.

NCT ID: NCT04456010 Completed - COVID19 Clinical Trials

COVID-19 in ART: Perception and Experience

COVAPEX
Start date: June 1, 2020
Phase:
Study type: Observational

Non-urgent medical care, such as fertility treatments, has been massively postponed during the past weeks due to the COVID19 pandemic. The lockdown and the closure of IVF centers might cause anxiety and depression among infertile couples, who are already exposed to the distressing experience of infertility and for whom the wait for a baby already appears unending. Few data are available regarding the impact of SARS-CoV-2 on pregnant women and foetus, or on fertility. This study aims to assess the views of infertile couple regarding the potential risks of COVID during their fertility treatment and their personal experience of the COVID pandemic and their expectation for further treatment .

NCT ID: NCT04396210 Completed - COVID Clinical Trials

Patients Perspectives on Discontinuation of Their Fertility Treatment Due to the COVID-19 Pandemic

Start date: May 14, 2020
Phase:
Study type: Observational

The COVID-19 pandemic brought new challenges to our nationwide healthcare system, with rapid escalation of the number of affected individuals over a handful of weeks. From March 13, a first set of measures was taken to minimise the spread of the virus, which largely impacted societal and economical daily life. A view days later, on March 17, the country was put in "lockdown" and all non-urgent medical treatments were cancelled or postponed. As recommended by the major scientific fertility societies, all non-ivf fertility treatments were discontinued abruptly, whereas started ivf stimulations were continued until oocyte aspiration, where after a freeze-all strategy was applied. There is little information available for women aiming for pregnancy or embarking on assisted conception. Given the modelling of the pandemic, including the time to peak and subsequent tail, considerable delays in conception to substantially attenuate risk may be required, which will inevitably impact patients wellbeing and overall success rates. A questionnaire was developed to explore patients perspectives on different aspects of their fertility treatment during the COVID-19 pandemic. The questionnaire contains the following sections: - demographic variables; - questions regarding the fertility history of the respondent; - questions regarding the impact of fertility treatment cancellation / postponing fertility treatment during COVID-19 on their life, psychological wellbeing and relationship; - questions regarding continuing medical treatment on their own, or seeking treatment elsewhere; - questions regarding the satisfaction of measures taken by their fertility center regarding the COVID-19 pandemic; - questions regarding expectations of further treatments, with focus on safety issues related to the COVID-19 pandemic. Eligible patients will be selected electronically from our database and digital agenda. After selection, patients will be contacted via email to participate. Two reminders will be send in case the questionnaire is not filled out: a first reminder after one week, a second reminder after two weeks.

NCT ID: NCT04395755 Completed - COVID-19 Clinical Trials

Impact of COVID-19 on Psychological Status in Case of IVF Interrupted or Postponed

Start date: April 1, 2020
Phase:
Study type: Observational

Infertility is a severely distressing experience for many couples. Depression and anxiety are psychological disorders associated with infertility, and they may worsen during infertility treatments. This study times to understand the changes in the psychological status of infertile patients who had in vitro fertilization (IVF) treatment interrupted or postponed because of the COVID-19 pandemic.

NCT ID: NCT04295083 Completed - ART Clinical Trials

Effect of Clay Based Group Study With Elderly Living Alone

Start date: December 27, 2017
Phase: N/A
Study type: Interventional

This study determines the effectiveness of clay-based group study on the loneliness and hopelessness levels in elderly living alone. For this, while the experimental group will six 1,5 h weekly of clay-based group study and interviewed face-to-face twice, the control group will interview face-to-face twice

NCT ID: NCT04253470 Completed - Female Infertility Clinical Trials

Debate on Progesterone Elevation on the Day of Triggering

PE
Start date: January 1, 2012
Phase:
Study type: Observational

The association between serum progesterone (P) levels, measured on the day of ovulation trigger, and the outcome of in vitro fertilization cycles, has been one of the major controversies in the field of ovarian stimulation endocrinology. This is a single-center retrospective cohort study. Study duration period is from January 2012 to December 2016. All fresh embryo transfer (ET) both at cleavage stage and blastocyst stage, performed in Humanitas Fertility Center during the study period, were included.

NCT ID: NCT04039217 Completed - HIV Clinical Trials

Antiretroviral Therapy (ART) Persistence in Different Body Compartments in HIV Negative MSM

Start date: September 30, 2019
Phase: Phase 4
Study type: Interventional

The study seeks to understand how anti-HIV drug Biktarvy, which contains the drugs tenofovir alafenamide (TAF), emtricitabine (FTC), and bictegravir (BIC) is absorbed and how long it persists in different body compartments, including mucosal tissues, as it may be considered for PrEP or PEP regimens in the future.

NCT ID: NCT03986099 Completed - ART Clinical Trials

Community Based Antiretroviral Therapy (CBART) Among Children on Chronic ART

CBART
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

A randomized, open label trial of two strategies for Virus Load Differentiated Care (VLDC) monitoring of virologic outcome in a rural community based treatment program in Zimbabwe.

NCT ID: NCT03822429 Completed - Fertility Disorders Clinical Trials

Cumulative Live Birth Rate (CLBR) After a Complete IVF Cycle: a Single Center Retrospective Study

Start date: January 1, 2010
Phase:
Study type: Observational

We need to identify a new parameter to evaluate the success rate of IVF techniques. CLBR has been suggested as a suitable way for reporting success of IVF program: it implies capturing the totality of live birth episodes following successive treatments. For patients CLBR is easy to understand because it summarizes the chance of a live birth over an entire treatment period. CLBR per oocyte retrieval is more meaningful as it is the best indicator of quality and success in IVF and it allows the best indicator of quality and success in IVF with different strategies for freezing embryos.

NCT ID: NCT03808194 Completed - HIV Infections Clinical Trials

Lotto to Link Study: A Prospective, Interventional, Randomized Study of Conditional Incentives

Start date: October 26, 2017
Phase: N/A
Study type: Interventional

In this study the investigators will adapt and strengthen, test effectiveness, and explore implementation of conditional lottery incentive linkage strategies to engage men in HIV care and ART in KwaZulu-Natal, South Africa.