Factors Affecting the Endodontic Treatment Outcome

Apical Periodontitis Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05221450
• Other study ID #: 0120-402/2019/5
• Status: Recruiting
• Start date: January 1, 2008
• Est. completion date: December 2028

Study information

• Verified date: April 2024
• Source: Odontos, Specialisticna Zobna Ambulanta, d.o.o.
• Contact: Rok Juric, DMD
• Phone: +386 1 2323231
• Email: rok.juric[@]odontos.si
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this prospective cohort observational study is: (i) to assess the endodontic treatment outcome in a private specialist endodontic office in Slovenia; (ii) to estimate the effect of various pre-, intra- and postoperative factors onto endodontic treatment outcome.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 700
• Est. completion date: December 2028
• Est. primary completion date: December 2027
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• patients referred to the private endodontic specialist office for endodontic treatment
• written informed consent was obtained prior beginning of the treatment.

Exclusion Criteria:

• preoperative advanced periodontal disease
• prior microsurgical root-end resection performed
• apices of the tooth were not clearly discernible on any of periapical radiographs
• endodontic treated teeth were extracted for non-endodontic reason
• the patient did not attend a follow-up examination.

Related Conditions & MeSH terms

• Apical Periodontitis
• Granuloma
• Periapical Periodontitis
• Periodontitis

Intervention

Procedure:
• primary endodontic treatment

Locations

Country	Name	City	State
Slovenia	Odontos, specialisticna zobna ambulanta, d.o.o.	Ljubljana

Sponsors (2)

Lead Sponsor	Collaborator
Odontos, Specialisticna Zobna Ambulanta, d.o.o.	University of Ljubljana, Faculty of Medicine

Country where clinical trial is conducted

Slovenia, 

References & Publications (6)

European Society of Endodontology. Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int Endod J. 2006 Dec;39(12):921-30. doi: 10.1111/j.1365-2591.2006.01180.x. — View Citation

Friedman S, Abitbol S, Lawrence HP. Treatment outcome in endodontics: the Toronto Study. Phase 1: initial treatment. J Endod. 2003 Dec;29(12):787-93. doi: 10.1097/00004770-200312000-00001. — View Citation

Ng YL, Mann V, Gulabivala K. A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health. Int Endod J. 2011 Jul;44(7):583-609. doi: 10.1111/j.1365-2591.2011.01872.x. Epub 2011 Mar 2. — View Citation

Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. Outcome of primary root canal treatment: systematic review of the literature - part 1. Effects of study characteristics on probability of success. Int Endod J. 2007 Dec;40(12):921-39. doi: 10.1111/j.1365-2591.2007.01322.x. Epub 2007 Oct 10. — View Citation

Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. Outcome of primary root canal treatment: systematic review of the literature -- Part 2. Influence of clinical factors. Int Endod J. 2008 Jan;41(1):6-31. doi: 10.1111/j.1365-2591.2007.01323.x. Epub 2007 Oct 10. — View Citation

Ricucci D, Russo J, Rutberg M, Burleson JA, Spangberg LS. A prospective cohort study of endodontic treatments of 1,369 root canals: results after 5 years. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):825-42. doi: 10.1016/j.tripleo.2011.08.003. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Treatment outcome based on strict combined radiographic and clinical criteria	Successful treatment outcome is defined as an absence of radiographic sign of apical periodontitis (periapical index PAI <= 2) and clinical signs of inflamation (swelling, sinus tract, tenderness to periapical palpation and percussion, pain) on follow-up examination 1-4 years postoperatively	1-4 years postoperatively