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Clinical Trial Summary

The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia.


Clinical Trial Description

In June 2016, an intranasal delivery system of local anesthesia called Kovanaze, gained FDA approval. Kovanaze is available as a 0.2 ml metered spray and is intended to achieve pulpal anesthesia of 5 maxillary teeth on either side of the face.

With the ability to avoid the traditional painful injection Kovanaze offers promise in the field of maxillary anesthesia and this study intends to:

1. Compare Kovanaze to conventional needle anesthetic in adults

2. Evaluate patient anxiety, tolerance and acceptability of Kovanaze in patients undergoing dental procedures ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04104789
Study type Interventional
Source Virginia Commonwealth University
Contact
Status Withdrawn
Phase Phase 2
Start date September 2020
Completion date October 2021

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