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Anxiety and Depression clinical trials

View clinical trials related to Anxiety and Depression.

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NCT ID: NCT06188923 Not yet recruiting - Clinical trials for Anxiety and Depression

A New Intervention to Improve Function in Veterans With Anxiety and Depression

Start date: October 1, 2024
Phase: Phase 2
Study type: Interventional

Anxiety and depression symptoms occur at high rates in Veteran populations and can significantly impact function, compromising the ability to work and to successfully form and maintain valued relationships. Several other symptoms commonly occur with anxiety and depression, including poor sleep quality and chronic pain. Since all these symptoms frequently occur together, they may have a common underlying biological basis. A single medication that could effectively treat all these symptoms would be ideal. Converging data suggest that pregnenolone is a promising pharmacological agent for treating multiple psychiatric symptoms and functional impairment. The investigators thus propose to conduct a clinical trial of pregnenolone in Veterans with anxiety and depression symptoms. Pregnenolone has minimal side effects, and the prior research demonstrates that pregnenolone is well-tolerated by Veterans. Treatment with pregnenolone could thus be an efficacious new therapeutic for Veterans experiencing depression, anxiety, poor sleep quality and chronic pain conditions.

NCT ID: NCT06116812 Recruiting - Breast Cancer Clinical Trials

The Effect of Laughter and Mindfulness Therapy Applications on Women With Breast Cancer Receiving Chemotherapy: Randomized Controlled Study

Start date: January 1, 2024
Phase: N/A
Study type: Interventional

Breast cancer is defined as the most common type of cancer that causes death among women (Siegel et al. 2019). It constitutes 24% of cancers and 15% of cancer-related deaths in women (T.R. Ministry of Health 2020). According to statistics made towards the end of 2020, there are 7.8 million women in the world who were diagnosed with breast cancer in the last 5 years and are alive. It is estimated that one in every 8 women will develop breast cancer in developed countries (WHO 2021). The Ministry of Health reported the frequency of breast cancer in our country as 45.6/100,000 in women in 2018. The incidence of breast cancer is reported to be higher, especially in the 45-54 age range (TC Ministry of Health 2020). Chemotherapy is one of the most frequently preferred treatment methods in the treatment of breast cancer and can cause serious side effects such as pain, nausea and vomiting, loss of appetite, shortness of breath, mouth sores, fatigue, insomnia, anxiety and depression, and may lead to a deterioration in the quality of life of patients (Waks and Winer 2019, Samami et al. 2021, Sajadian et al. 2017, McFarland et al. 2018, Hamer et al. 2017). In the international and national literature, no study has been found comparing the effects of laughter and mindfulness therapy on the anxiety, depression, quality of life and spiritual well-being experienced by breast cancer patients. In this study, it is planned to investigate the effects of laughter and mindfulness therapy applications on the anxiety, depression, quality of life and spiritual well-being levels of women with breast cancer receiving chemotherapy.

NCT ID: NCT05747092 Recruiting - Clinical trials for Anxiety and Depression

Pain Killer, Anxiety and Mucogingival Therapy

Start date: January 14, 2022
Phase: N/A
Study type: Interventional

Is the pain killer consumption after gingival treatment related to the level of patient anxiety or to the type of therapy?

NCT ID: NCT04989972 Withdrawn - Clinical trials for Anxiety and Depression

Assessing the Efficacy of Micro-dosed Psilocybin on Reducing Anxiety & Depression Levels in Adults

Start date: September 15, 2022
Phase: Phase 2
Study type: Interventional

To investigate the efficacy of a 16 week treatment with PSIL428 patient reported anxiety levels in otherwise healthy individuals suffering from depression and or anxiety symptoms.

NCT ID: NCT04925765 Completed - Pregnancy Related Clinical Trials

Virtual Reality Biofeedback for Postpartum Anxiety and Depression

VITALISE
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to test patient feasibility and acceptability of virtual reality biofeedback program in postpartum women for anxiety and depression outcomes.

NCT ID: NCT01197313 Completed - Exercise Clinical Trials

Depression and Quality of Life in Chronic Heart Failure Patients and the Caregivers

Start date: December 2006
Phase: N/A
Study type: Interventional

Anxiety and depression are often present in patients with chronic heart failure (CHF). This study aimed to evaluate the influence of anxiety and depression on the physical function, disability, and quality of life (QOL) in CHF. This study examined the effects of 8-week home-based exercise on these parameters, and investigated the correlations between these outcome changes.