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Aneurysm clinical trials

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NCT ID: NCT01372709 Completed - Clinical trials for Abdominal Aortic Aneurysm

TriVascular Post-Market Registry

Start date: May 2011
Phase:
Study type: Observational

This is a prospective observational post-market study of subjects receiving the Ovation™ or Ovation Prime™ Abdominal Stent Graft System ("Ovation™ or Ovation Prime™ Abdominal Stent Graft System Post-Market Study") in the treatment of abdominal aortic aneurysms (AAA). The Ovation™ or Ovation Prime™ Abdominal Stent Graft System Post-Market study is intended to expand the clinical knowledge base by collecting data on subjects treated with the Ovation™ or Ovation Prime™ Abdominal Stent Graft System in actual clinical practice following commercial approval.

NCT ID: NCT01354184 Completed - Clinical trials for Abdominal Aortic Aneurysm

CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)

Start date: n/a
Phase: Phase 2
Study type: Interventional

This is an investigation of the efficacy and safety of CRD007 compared to placebo in the treatment of patients with abdominal aortic aneurysm.

NCT ID: NCT01353443 Completed - Clinical trials for Abdominal Aortic Aneurysm

Prophylactic Mesh Implantation After Abdominal Aortic Aneurysm Repair

Start date: February 2011
Phase: N/A
Study type: Interventional

AIDA Study is a prospective, multicentre, randomized, controlled clinical investigation with patients undergoing median laparotomy for Abdominal Aortic Aneurysm (AAA) repair. The primary objective of the clinical investigation is to test the hypothesis that insertion of an Optilene® Mesh Elastic mesh - a monofilament, light-weight, large pore sized, polypropylene mesh manufactured by Aesculap AG - is superior to suturing alone and will reduce the hernia formation rate within the first 2 years. A reduction from 30% to 10% of the patient population is assumed.

NCT ID: NCT01349582 Completed - Clinical trials for Intracranial Aneurysm

Flow Diversion in Intracranial Aneurysm Treatment

FIAT
Start date: May 2, 2011
Phase: N/A
Study type: Interventional

Flow diverters are a recent addition to the range of endovascular devices now available for the treatment of intracranial aneurysms. The FIAT trial aims at comparing flow diversion to best standard treatment in the context of a randomised controlled trial. Best standard treatment may include any of the following and will be left to the treating physician to decide : 1) conservative management; 2) coiling with or without high porosity stenting; 3) parent vessel occlusion with or without bypass; 4) surgical clipping. If the only treatment alternative is deemed to be flow diversion for compassionate use, then randomisation will not be carried out, but patient will enter a registry and her data recorded according to same schedule as randomised patients. The primary hypothesis is that flow diversion can be performed with an "acceptable" immediate complication rate, defined as less than 15% morbidity and mortality, AND increase the number of patients experiencing successful therapy, defined as complete or near complete occlusion of the aneurysm from 75 to 90%, relative to best standard treatment.

NCT ID: NCT01348828 Completed - Clinical trials for Abdominal Aortic Aneurysm

Feasibility and Safety Study of the Endologix Fenestrated Stent Graft System

Start date: October 19, 2011
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the safety and feasibility of the Endologix Fenestrated Stent Graft System for the endovascular repair of juxtarenal or pararenal aortic aneurysms.

NCT ID: NCT01344239 Completed - Clinical trials for Abdominal Aortic Aneurysm

Limb Remote Ischemic Preconditioning Reduces Heart and Lung Injury After Abdominal Aortic Aneurysm Repair

Start date: January 2008
Phase: N/A
Study type: Interventional

To investigate whether limb remote ischemic preconditioning (LRIP) has protective effects against intestinal and pulmonary injury in patients undergoing open infrarenal abdominal aortic aneurysm (AAA) repair.

NCT ID: NCT01340612 Completed - Clinical trials for Intracranial Aneurysm

Stenting in the Treatment of Aneurysm Trial

STAT
Start date: August 25, 2011
Phase: N/A
Study type: Interventional

The STAT trial aims at comparing coiling versus coiling plus stenting in patients with aneurysms prone to recurrence, that is large aneurysms or recurring aneurysms after previous coiling or wide-necked aneurysms. The primary hypothesis is that the use of stenting in addition to coiling decreases the recurrence rate from 33% to 20% at 12 months as compared to coiling alone.

NCT ID: NCT01328197 Completed - Clinical trials for Abdominal Aortic Aneurysms

Treovance Stent-Graft With Navitel Delivery System for Patients With Infrarenal Abdominal Aortic Aneurysms

Start date: June 2011
Phase: Phase 1
Study type: Interventional

The primary goal of the study is to assess the safety and performance of the Treovance device in subjects with infrarenal aortic aneurysms, specifically to evaluate if the diseased pathology can be treated with an acceptable adverse event rate and that the device performs as expected. The results of this study will permit the establishment of endpoints and clinical design for a subsequent U.S. trial.

NCT ID: NCT01326884 Completed - Clinical trials for Abdominal Aortic Aneurysm

Zenith Low Profile AAA Endovascular Graft (ZLP) Clinical Study

ZLP
Start date: February 2011
Phase: N/A
Study type: Interventional

A prospective study conducted in Japan to collect confirmatory peri-operative and 30-day information on use of the Zenith LP AAA Graft.

NCT ID: NCT01323439 Completed - Aneurysm Clinical Trials

Axium™ MicroFX™ for Endovascular Repair of IntraCranial Aneurysm-A Multicenter Study

AMERICA
Start date: April 2010
Phase: N/A
Study type: Observational

This is a multicenter, prospective single-arm trial evaluating the safety and efficacy of the Axium MicroFX coil system in 100 aneurysms.