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Anesthesia clinical trials

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NCT ID: NCT03261115 Completed - Anesthesia Clinical Trials

Effects of Benzocaine 20% Topical Anesthetic and no Topical Agent on Pain Perception During Intra-oral Injections

Start date: August 16, 2017
Phase: N/A
Study type: Interventional

The aim of this randomized controlled trial. is to test the efficacy of topical anesthesia against the use of no topical agent during buccal infiltration in maxillary anterior teeth. The rationale behind this comparison is to evaluate the practical, clinical outcome of not using any topical agent if in fact topical anesthesia does not reduce pain as reported by various studies and if consequently its usage was to be discontinued.

NCT ID: NCT03255824 Completed - Anesthesia Clinical Trials

A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation

Start date: March 20, 2018
Phase: Phase 4
Study type: Interventional

Hypothesis: A combination of midazolam with dexmedetomidine for sedation during third molar surgery will provide 1) superior patient satisfaction, 2) superior operator satisfaction and 3) no significant hemodynamic or respiratory changes when compared to a sedation combination of midazolam, fentanyl and propofol for sedation during third molar surgery.

NCT ID: NCT03251105 Completed - Surgery Clinical Trials

Supreme Versus Proseal Laryngeal Mask Airways in Infants

Start date: April 27, 2016
Phase: N/A
Study type: Interventional

In this study, the Supreme and ProSeal LMAs in infants were compared by measuring their performance characteristics, including insertion features, ventilation parameters, induced changes in hemodynamics and rates of postoperative complications.

NCT ID: NCT03248908 Completed - Anesthesia Clinical Trials

Pupillary Dilation Reflex Assessment for Intraoperative Analgesic Titration.

PUP-AIT
Start date: October 12, 2017
Phase: N/A
Study type: Interventional

In this double blinded randomized controlled study, the pupillary dilation reflex is used for as a nociceptive indicator for opioid administration during elective surgery under general anesthesia.

NCT ID: NCT03247998 Not yet recruiting - Stroke Clinical Trials

GA vs. CS for Endovascular Stroke Therapy

Start date: August 31, 2017
Phase: N/A
Study type: Interventional

After a stroke caused by a blockage (clot) in a blood vessel in the brain, patients may have the clot removed by threading a catheter from the groin up to the affected area of the brain. An anesthesiologist is involved in the patient's care during this procedure to maximize patient safety and procedural efficiency. The options for anesthesia for this procedure are general anesthesia (where the patient is unconscious) or sedation (where the patient is in a relaxed, calm, sleepy condition). Currently, it is unclear which of these anesthetic options contributes to the best patient outcome. The investigators would like to investigate whether or not one method of anesthesia (general or sedation) is better to use than the other when removing the clot.

NCT ID: NCT03244436 Completed - Anesthesia Clinical Trials

Emergency Surgery Following Pediatric Catheterization

Start date: June 15, 2013
Phase: N/A
Study type: Observational

We study the outcome and prequesties of emergency surgeries that were necessary following accidents in the pediatric cardiac catheterization lab

NCT ID: NCT03241004 Terminated - Anesthesia Clinical Trials

Does Melatonin Affect Anesthetic MAC (Minimum Alveolar Concentration)?

Start date: July 7, 2017
Phase: N/A
Study type: Interventional

This study aims to determine if anesthetic depth can be deepened non-pharmacologically through use of sleep masks. This study seeks to demonstrate a relationship between the depth of anesthesia with application of sleep masks intraoperatively and in the critical care setting.

NCT ID: NCT03240354 Completed - Anesthesia Clinical Trials

Paediatric Microcuff Pressure Study

MicroCuff
Start date: August 6, 2018
Phase: N/A
Study type: Interventional

In paediatric anaesthesia, use of cuffed endotracheal (ET) tubes is subject to much debate. The concern is the possibility of damage to tracheal mucosa by excessive pressure from the cuff. The cuff pressure can increase during anaesthesia, especially if nitrous oxide is used. Using saline to inflate the cuff has been shown to reduce intra-operative cuff pressure variation in adult studies, although it is not standard practice. Although the literature contains reports of cuff pressure increases during paediatric anaesthesia, there are no reports of attempts to address this. Use of pressure monitoring is recommended by AAGBI, but may not be consistently done. A safe method of limiting pressure, that is effective, imposes minimal extra workload and has minimal cost, would reduce risk to patients. This study aims to investigate the effect on intra-operative cuff pressure of using saline to inflate the ET tube cuff, compared to standard practice of air inflation. Continuous pressure monitoring will be used to determine the proportion of cases where interventions are required to keep the pressure below a safe maximum level.

NCT ID: NCT03238625 Completed - Anesthesia Clinical Trials

Painless Local Anaesthesia With Bicarbonate Admixture

Start date: August 1, 2017
Phase: Phase 2
Study type: Interventional

This study examines whether the injection of local anesthesia mixed with sodium bicarbonate in the ratio of 3:1 creates a less burning sensation and is as effective regarding the anesthetic effect as in the ratio of 9:1.

NCT ID: NCT03231696 Completed - Anesthesia Clinical Trials

Visibility - Classification of Sono-visibility of Anatomical Structures in Peripheral Nerve Blocks

Visibility
Start date: January 2012
Phase: N/A
Study type: Observational

We assessed the visibility of peripheral nerves while ultrasound guided blockades with a novel scoring system to evaluate differences in visibility of different nerves.