Clinical Trials Logo

Anesthesia clinical trials

View clinical trials related to Anesthesia.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT06370130 Completed - Anesthesia Clinical Trials

Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion

Start date: May 1, 2022
Phase: Early Phase 1
Study type: Interventional

Objective To prospectively determine the median effective dose (ED50) of propofol for inhibiting a response to laryngeal mask airway (LMA) insertion when combined with different doses of esketamine in female patients. Methods Fifty-eight female patients (aged 20-60, ASAⅠ-Ⅱ) scheduled for elective hysteroscopy were enrolled and randomly divided into two groups, one administered 0.2 mg/kg of esketamine (K1 group, n = 28) and the other 0.3 mg/kg of esketamine (K2 group, n = 30). The two groups received the corresponding doses of esketamine intravenously, followed by an intravenous injection of propofol (injection time was 30 s). The initial dose of propofol was 2 mg/kg, and the dose ratio of propofol in the adjacent patients was 0.9. If there was a positive reaction to LMA insertion, the dose ratio in the next patient was increased by one gradient, and if not, the dose ratio was decreased by one gradient. The median effective dose (ED50), 95% effective dose (ED95) and 95% confidence interval (95%CI) of propofol for inhibiting a response to LMA insertion in the two esketamine groups were calculated using a probit analysis.

NCT ID: NCT06358183 Completed - Surgery Clinical Trials

Surgical Capacity in Zimbabwean Public Hospitals

Start date: April 24, 2019
Phase:
Study type: Observational

This study aimed to understand how ready Zimbabwe's public hospitals are to perform essential surgeries, which are critical for treating a wide range of health issues from emergencies like car accidents to planned procedures such as childbirth by caesarean section. The researchers looked at hospitals across Zimbabwe to see what kind of surgery facilities, equipment, and specialists were available.

NCT ID: NCT06356649 Completed - Anesthesia Clinical Trials

Investigation of the Effects of Pressure Support Ventilation and Positive Airway Pressure Modes During Extubation

Start date: March 15, 2023
Phase:
Study type: Observational [Patient Registry]

Controlled ventilation is applied to patients intubated for general anesthesia. Additionally, positive end-expiratory pressure (PEEP) and pressure support are mechanical ventilation modes that have been used in general anesthesia practice for many years. When the recovery-extubation phase is reached, intermittent bag-mask ventilation is usually used and the patient is allowed to breathe spontaneously and is extubated when an adequate respiratory level is reached. It has been shown in previous studies that the use of intermittent mask ventilation causes postoperative atelectasis. Different methods have been used to prevent postoperative atelectasis. In our study, we aimed to observe the effect of terminating general anesthesia at the end of the operation and using PEEP and pressure-supported ventilation during the extubation phase on early complications.

NCT ID: NCT06320691 Completed - Anesthesia Clinical Trials

General vs Spinal Anesthesia for Total Joint Arthroplasty-Anterior Approach: A Single-Institution Observational Study

Start date: January 10, 2014
Phase:
Study type: Observational

The study compares the effects of various anesthetic techniques on anterior approach total hip arthroplasty results retrospectively

NCT ID: NCT06314984 Completed - Anesthesia Clinical Trials

Jet Injectors Versus Conventional Anesthetic Technique in Children

Start date: July 21, 2021
Phase: N/A
Study type: Interventional

This clinical study was conducted to compare the needleless Comfort-in jet injector device and the conventional needle technique in terms of 1. Pain level during the administration of local anesthesia in children. 2. Their effectiveness during pulpotomy procedures in primary molars. Whether comfort-in jet injector device will achieve sufficient anesthesia for the procedures undertaken during pulpotomy or not when compared to the conventional technique and the pain levels of both techniques during the anesthesia step.

NCT ID: NCT06271161 Completed - Postoperative Pain Clinical Trials

The Effect of Pharyngeal Cooling Applications on Postoperative Throat Pain and Nausea Vomiting

Start date: January 1, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to to evaluate the effects of a throat pack soaked with saline at +4 ºC on postoperative throat pain (POTP) and postoperative nausea and vomiting (PONV) in dental surgical procedures performed under general anesthesia. The main questions it aims to answer are: 1. How long can we keep the pharyngeal mucosa cold using tampons and cold wash solutions? 2. Does cooling the pharyngeal mucosa reduce the incidence of postoperative sore throat and nausea and vomiting?

NCT ID: NCT06249659 Completed - Surgery Clinical Trials

Impact of Extubation Location After Surgery on Perioperative Times

Extub_Loca
Start date: September 1, 2020
Phase:
Study type: Observational

The additional time required to awaken a patient is one of the main reasons for not extubating him or her in the operating room (OR). Conversely, transferring an intubated patient to recovery room (RR), prolonging the duration of anesthesia and intubation, in a limited environment in human resources, may lead to increased complications' rates. Little is known about those time lengths and complications rates.

NCT ID: NCT06228040 Completed - Anesthesia Clinical Trials

Is Pre-anaesthetic Teleconsultation a Safe Alternative to Traditional Pre-anaesthetic Consultation?

Start date: January 18, 2024
Phase: N/A
Study type: Interventional

A pre-anaesthetic consultation is compulsory. It must be carried out at least 8 days before a scheduled medical and/or surgical operation. Its main objectives are to take the patient's history, carry out a clinical examination, select the complementary examinations that should be carried out, and inform the patient of the procedure and the type of anaesthetic proposed. In a world moving towards virtualisation, a number of medical specialities have opted for remote consultations, either by telephone or video-conferencing. Teleconsultation seems to offer greater satisfaction, not only for patients, but also for surgeons and anaesthetists. It is also associated with a reduction in the distance travelled by patients, costs and financial expenditure, with no increase in the rate of cancellation of surgery. For the first time at the Brussels University Hospital (Erasme), the anaesthesia and intensive care team will gradually introduce the system of pre-anaesthetic teleconsultation by telephone from October 2023. The aim of our study is to evaluate the effectiveness of preanaesthetic teleconsultation at the Erasme HUB. In fact, it would be better to have results based on local expertise in order to give an answer on the effectiveness, safety and security of this innovative method, which will be officially implemented in October 2023.

NCT ID: NCT06214169 Completed - Anesthesia Clinical Trials

Effect of Addition of Cisatracurium to Lidocaine VS Plain Lidocaine

Start date: June 15, 2023
Phase: N/A
Study type: Interventional

The goal of this Randomized Control Trial is to compare the effects of addition of cisatracurium to lignocaine for IVRA Vs. Plain lignocaine in All ASA physical status I & II patients between 20 to 55 years of age, scheduled for elective hand surgery (carpal tunnel, trigger finger, tendon release, fracture reduction and tendon repair). The main question[s] it aims to answer are: • Does addition of Cisatracurium to plain lignocaine improve the overall quality of anesthesia? • Does use of cisatracurium lead to improved postop analgesia and decreased parenteral analgesic requirements? Participants will be Forty-four patients undergoing elective hand surgery during IVRA randomly assigned to two groups of 22 patients each. All demographic details (age, gender, body weight) will be noted, all will be briefed about visual analogue score (0 to 10) for pain. Group 1 (control group) will receive lidocaine 2% diluted with saline, group 2 (cisatracurium group) will receive cisatracurium plus lidocaine 2% diluted with saline. A standard technique would be employed for IVRA. The following parameters to be assessed: onset and offset of sensory and motor block, Intra-operative pain at 5, 10, 20, 30 minutes after tourniquet application by using visual analogue score (VAS), and postoperative pain using visual analogue score (VAS) measured at 5-minute,1, 2, 4, 8 hours postoperatively.

NCT ID: NCT06192082 Completed - Anesthesia Clinical Trials

Adverse Cardiovascular Events During Painless Gastroscopy Diagnosis and Treatment in Elderly Frail Patients

frail
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

This study aims to compare the effects of conscious sedation and intravenous general anesthesia on cardiovascular events in frail patients undergoing digestive endoscopy diagnosis and treatment.