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Anesthesia clinical trials

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NCT ID: NCT03910179 Recruiting - Anesthesia Clinical Trials

Dynamic Arterial Elastance During General Anesthesia Induction

Start date: September 10, 2019
Phase:
Study type: Observational

This study evaluates if dynamic arterial elastance measured before general anesthesia induction can predict the occurrence of hypotension due to general anesthesia induction.

NCT ID: NCT03903991 Completed - Anesthesia Clinical Trials

Evaluation of the Reliability of Oesophageal Temperature in THOracic Surgery

ThoTem
Start date: July 18, 2019
Phase:
Study type: Observational

Controlling hypothermia is essential in anesthesia to limit postoperative complications. Temperature monitoring is therefore essential. However, the reliability of esophageal temperature during open chest lung surgery is discussed and not accurately assessed in the literature.

NCT ID: NCT03901599 Completed - Anesthesia Clinical Trials

Protective Ventilation Based on Alveolar Ventilation in Children

PROVENTIPED
Start date: May 16, 2019
Phase:
Study type: Observational

Protective ventilation decreased morbidity and mortality in adults' patients and is now a standard of care in intensive care unit and in anesthesiology. In children, there is no evidence in the literature to recommend protective ventilation during anaesthesia. Moreover the ratio of instrumental dead space to tidal volume is higher in children than in adults. Therefore, it is difficult to propose an "optimal" tidal volume for all children. The objective of this study is to evaluate the use of alveolar ventilation (estimated by the volumetric capnography) in children under anesthesia. The hypothesis is that in children, alveolar ventilation reported to ideal body weight is a constant to maintain normocarbia, unlike the tidal volume.

NCT ID: NCT03897985 Completed - Anesthesia Clinical Trials

Measurement of Anaesthesia-depth Trough Narcotrend TM in Patients Undergoing Electro-Convulsion-Therapy (ECT)- Influence of Anasthesia Depth on Quality of Convulsion

TM TradeMark
Start date: May 1, 2019
Phase:
Study type: Observational

The Electro-Convulsion-Therapy (ECT) is a well accepted treatment option in severe depression. The quality of ECT is evaluated basing on minimal seizure duration (>15sec), the sympathic response and the postictal EEG-suppression. For the treatment general anaesthesia is needed. On the other hand anaesthesia strongly influences the quality of the seizure. The goal is to find an anaesthesia-depth that is needed for the well-being of the patient and allows a good ECT. In daily routine the dose of anesthetic agents and the assesment of anesthesia-depth is based on the subjective estimation of the anesthetist and also on ealier interventions. The aim of the study is to assess any correlation between measured anesthesia-depth using the Narcotrend TM and the Quality of the ECT.

NCT ID: NCT03894904 Completed - Anesthesia Clinical Trials

Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients

Start date: April 1, 2019
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare intraoperative papaverine plus heparin to heparin alone for prevention of arterial spasm and maintenance of patency of peripheral arterial catheters during surgery in pediatric patients. The hypothesis is that periodic, intraoperative small-volume boluses of diluted papaverine plus heparin in peripheral arterial catheters of pediatric patients will prevent arterial spasm and help maintain patency of arterial catheters during general anesthesia.

NCT ID: NCT03891342 Completed - Surgery Clinical Trials

Effect of Fluid Challenge on Glycocalyx

Start date: February 2016
Phase: N/A
Study type: Interventional

Interventional study comparing effect of two regimes of fluid challenge in patients with sepsis and in patients undergoing elective major surgery on glycocalyx by using perfused Boundary Region in sublingual microcirculation.

NCT ID: NCT03887949 Recruiting - Anesthesia Clinical Trials

Comparison of Three Modes of Ventilation During Robot-assisted Hysterectomy in Trendelenburg Position

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Robot-assisted hysterectomy is associated with pneumoperioneum with CO2 and Trendelenburg position, which may have adverse cardiopulmonary effects. A new ventilation mode; pressure-controlled ventilation with volume guaranteed mode (PCV-VG) delivers constant tidal volume with constant inspiratory pressure, using a decelerating flow pattern. This prospective, randomized study is designed to compare the effects of PCV-VG, volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) on respiratory and hemodynamic variables in patients undergoing Robot-assisted hysterectomy.

NCT ID: NCT03882541 Completed - Pain Clinical Trials

Could Music be an Alternative to Sedation in Patients Treated Total Knee Arthroplasty With Regional Anesthesia?

Start date: January 8, 2017
Phase: N/A
Study type: Interventional

Background: Anxiety is a common phenomenon in hospitalized patients. In order to reduce it during the surgical procedure, sedatives and anxiolytics are used, which can cause undesirable side effects for patients. Music is described as an effective tool to reduce this anxiety suffered by the patient in the perioperative process. Objectives: To evaluate the effect of music in patients anxiety and pain during perioperative process in surgical intervention with regional anaesthesia without sedatives or anxiolytics. Design: A randomized parallel clinical trial study with single-blinded and three harms. Setting: Operating theater of a public district hospital (serving around 111.000 people) Participants: All patients operated of Total Knee Arthroplasty (TKA) with regional anaesthesia with age between 50 and 85 years old within level I or II of the classification of the American Society of Anaesthesiologists (ASA). Methods: A total of 81 patients for TKA were randomly assigned to: a control group (headphones without music, without sedation), a sedative group (headphones without music, with sedation) and a experimental group (headphones with music, without sedation). 27 participants for each group. All the participants were using headphones so that it was a single-blinded study. The experimental group were provided with the same music, Piano Guys group. The variables of study were: the pain was measured by vale numerical scale (VNS), the anxiety was measured by the use of State-Trait Anxiety Inventory (STAI), heart rate (HR) variability, blood pressure (BP) variability, saturation of oxygen (Sat02). Relevance to Clinical Practice: sedation that can causes unwanted side effects by surgical patients can be replaced by music. The music decrease anxiety and pain values in orthopaedic surgery patients. Keywords: Anxiety, Drugs, Music therapy, Pain, Perioperative, Surgery.

NCT ID: NCT03875742 Completed - Anesthesia Clinical Trials

Interfascial Blocks Executed by Novice Operators in a Simulator Model: a Comparison of Two Types of Needles

Start date: May 20, 2019
Phase: N/A
Study type: Interventional

This study will compare two different needles for interfascial blocks. All participants will execute the block on simulator with both needles. The participants will be randomized in two groups to choose the starting needle.

NCT ID: NCT03872635 Completed - Anesthesia Clinical Trials

Effects of Anesthesia on Tumor Immunity and Insulin Resistance During Perioperative Period

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

To evaluate the effects of preoperative oral carbohydrate on postoperative insulin resistance and tumor immunity in cervical cancer patients with neoadjuvant chemotherapy.