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Anesthesia clinical trials

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NCT ID: NCT05609955 Completed - Surgery Clinical Trials

Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac

Start date: January 1, 2022
Phase: Phase 4
Study type: Interventional

This study aims to compare two groups of post-orthopedic patients who received a standard regimen, namely ketorolac 30mg, to the second group, which was given the standard regimen and adjuvant magnesium sulfate 30mg/kgBW 1 hour preoperatively. If it is proven useful, it is hoped that pain will be more controlled, reduce pain complications, reduce treatment costs, and reduce the duration of hospital stays.

NCT ID: NCT05601622 Not yet recruiting - Anesthesia Clinical Trials

RPVI for Fluid Responsiveness in Children

Start date: November 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to validate Rainbow pleth variability index for prediction of fluid responsiveness in children.

NCT ID: NCT05601427 Recruiting - Anesthesia Clinical Trials

Intra-Operative Adductor Canal Blocks

Start date: March 22, 2023
Phase: N/A
Study type: Interventional

Adductor canal blocks (ACB) have been recommended in total knee arthroplasty (TKA) to provide better control of post-operative pain, facilitate early ambulation, and reduce length of stay in the hospital. ACB is typically done before surgery by an anesthesiologist, which may increase time per case, cost, and requires the specialized skills of an anesthesiologist trained in regional anesthesia. Recent studies have suggested that surgeons can safely and reliably administer the adductor canal blocks (sACB) during surgery. However, there is currently very limited data on the clinical efficacy of such sACBs, and no studies assessing this technique in the context TKA that are discharged the same day. As such, this randomized control trial (RCT) is being done to compare sACBs to conventional anesthesiologist-performed adductor canal blocks (aACB).

NCT ID: NCT05590312 Recruiting - Anesthesia Clinical Trials

Comparison of Total Oxidant and Total Antioxidant Capacities in Low-Flow and High-Flow General Anesthesia

Start date: August 1, 2022
Phase:
Study type: Observational

The goal of this observational study is to determine whether low-flow anesthesia has a positive contribution to the total oxidant/antioxidant balance.

NCT ID: NCT05570682 Recruiting - Anesthesia Clinical Trials

Manually Controlled Infusion vs Target Controlled Infusion for StrokeThrombectomy

HASTE
Start date: October 9, 2022
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial is to compare manual general anesthesia induction to general anesthesia induction guided by target controlled infusion system in cerebral ischemic stroke The main questions it aims to answer are: - Does target controlled infusion has a more favorauble hemodynamic profile than manual general anesthesia induction? - Do patients receiving general anesthesia with target controlled infusion system have a more favourable outcome? Participants will receive general anesthesia induction with a target controlled infusion system and will be compared to patients receiving manual general anesthesia induction.

NCT ID: NCT05569460 Recruiting - Anesthesia Clinical Trials

Construction of Perioperative Medical Data Platform and Its Typical Practice to Predict Postoperative Acute Moderate to Severe Pain With Machine Learning Models

Start date: October 2022
Phase:
Study type: Observational

Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in perioperative medical management.

NCT ID: NCT05566067 Not yet recruiting - Anesthesia Clinical Trials

Survey of Anesthesiology Residents' Perceptions of Critical Care Medicine as a Career

Start date: December 2023
Phase:
Study type: Observational

This study's goal is to investigate the reasons behind the decline in interest in critical care fellowships among anesthesia residents.

NCT ID: NCT05564741 Not yet recruiting - Anesthesia Clinical Trials

Acute Hip Fracture and Spinal Anaesthesia Injection Time

Start date: October 2022
Phase: Phase 4
Study type: Interventional

The systemic effects of spinal anesthesia is not fully known. Our aim of this study is to assess whether there is a difference in hemodynamic effects if the spinal dose is given fast (15s) or slow (90s) in elderly patients with acute hip fracture (AHF). Ninety (n=90) patients with AHF planned for surgery within 72h at our hospital will be enrolled in the study and randomly devided into two groups. The patients will receive one predetermined dose of spinal anesthesia followed by an advanced minimally-invasive hemodynamic monitoring through an arterial line using FloTrac-system. The hemodynamic parameters will be conducted 10 minutes prior to the spinal anaesthesia and 30 minutes after the spinal block is given. Hypotension was defined as a fall in MAP > 30 % or a MAP <65mmHg.

NCT ID: NCT05563025 Recruiting - Anesthesia Clinical Trials

Comparison of Time and Cost Efficiency in Arthroscopic Shoulder Surgery Under Regional Anesthesia vs General Anesthesia

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Start date: December 16, 2022
Phase:
Study type: Observational

Arthroscopic Shoulder surgery can be done not only under general anesthesia but also regional technics. In this study we aimed to compare the cost and time effectiveness of regional anesthesia and general anesthesia.

NCT ID: NCT05558826 Recruiting - Anesthesia Clinical Trials

Pressure Analysis of Trendelenburg Position Effect on Indices From Arterial Pressure

Start date: October 1, 2022
Phase:
Study type: Observational

Intraoperative fluid management is key component of care for patients undergoing surgery. Hypovolemia and hypervolemia both associate with increased morbidity, length of stay in the intensive care unit and mortality. Thus, maintaining adequate intravascular volume yet avoiding fluid overload is crucial to achieve optimal outcomes. Goal-directed fluid therapy based on arterial pressure waveform analysis is widely used for intraoperative fluid management and have been shown to improve surgical outcomes compared with conventional clinical assessment in several studies. However, dynamic indices of arterial pressure waveform analysis such as pulse pressure variation (PPV) and stroke volume variation (SVV) are altered by certain situations including elevated intra-abdominal pressure and Trendelenburg position. Intravascular fluid status might thus be misinterpreted. Carbon dioxide pneumoperitoneum with increased intra-abdominal pressure and Trendelenburg position are commonly seen in laparoscopic surgeries including colorectal, gynecological, and genitourinary procedures. Understanding how dynamic indices change in these clinical situations are essential for achieving appropriate intraoperative fluid management. This study focus on identifying the effects of different levels of intra-abdominal pressure and angles of Trendelenburg position on dynamic indices of arterial pressure waveform.