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Anesthesia clinical trials

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NCT ID: NCT00741351 Completed - Anesthesia Clinical Trials

Anesthesiological Strategies in Elective Craniotomy

Neuromorfeo
Start date: December 2007
Phase: Phase 3
Study type: Interventional

This protocol, NeuroMorfeo, aims to assess equivalence between volatile and intravenous anesthetics for neurosurgical procedures.

NCT ID: NCT00723164 Completed - Anesthesia Clinical Trials

Premedication on Sevoflurane Induction

Start date: October 2005
Phase: N/A
Study type: Interventional

The goal of this study was to investigate the effects of fentanyl-midazolam premedication during sevoflurane induction pertaining to time to loss of eyelash reflex (LER), time and conditions of insertion of proseal laryngeal mask airway (PLMA), as well as cardio-respiratory data. Participants' anxiety level was also evaluated.

NCT ID: NCT00702715 Completed - Anesthesia Clinical Trials

Comparison of 4.0 mg/kg Sugammadex at 1-2 Post Tetanic Counts (PTC) in Renal or Control Patients (19.4.328)(P05769)

Start date: September 2008
Phase: Phase 3
Study type: Interventional

The current trial was designed to investigate the effects of 4.0 mg.kg-1 of sugammadex on efficacy, safety and pharmacokinetics in subjects with severe renal impairment in comparison to subjects with normal renal function.

NCT ID: NCT00690495 Completed - Anesthesia Clinical Trials

Use of a Modified Propofol Emulsion in Adults

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether a modified propofol preparation shows any effect on the incidence of injection pain in adults undergoing elective surgery under general anesthesia. Study hypothesis: The use of a modified propofol preparation will reduce the incidence of injection pain in the study group.

NCT ID: NCT00675792 Completed - Anesthesia Clinical Trials

Comparison of Sugammadex Administered at 1-2 Post Tetanic Counts (PTCs) or Better With Neostigmine Administered as Per Standard of Care to Reverse Rocuronium-Induced Neuromuscular Blockade in Adults Undergoing Elective Open Abdominal Procedure (19.4.334) (P05774)

Start date: May 2008
Phase: Phase 3
Study type: Interventional

The primary purpose of this study is to compare the incidence of residual neuromuscular blockade at the time of tracheal extubation after reversal of rocuronium bromide-induced neuromuscular blockade by 4 mg/kg sugammadex with that of 50 µg/kg neostigmine. Residual neuromuscular blockade is defined as the fourth twitch to first twitch (T4/T1) ratio of < 0.90.

NCT ID: NCT00674388 Recruiting - Surgery Clinical Trials

The Pediatric Anesthesia Quality Improvement Project

WUS
Start date: February 2008
Phase:
Study type: Observational [Patient Registry]

The Study is designed to collect information about adverse events that occur in children undergoing anesthesia in participating hospitals. Demographic information will be collected on all anesthetics. An analysis of each adverse event will be performed and entered into the database. From this information we will devise strategies to prevent these adverse events.

NCT ID: NCT00670696 Withdrawn - Healthy Clinical Trials

A Study to Compare the Efficacy of Rapydan Versus Tetracaine Gel

Start date: April 2008
Phase: Phase 4
Study type: Interventional

Tetracaine gel 4% is a topical anaesthetic gel commonly used in the UK that contains 40 mg of tetracaine base per gram. Adequate anaesthesia can usually be achieved following a 30 minute application time for venopuncture and a 45 minute application time for venous cannulation. The hypothesis is that Rapydan medicated plaster is more effective than tetracaine gel in preventing venous cannulation related pain when applied for the recommended treatment durations of 30 minutes and 45 minutes respectively.

NCT ID: NCT00597740 Completed - Anesthesia Clinical Trials

Propofol Sedation Study

SPIN
Start date: December 2007
Phase: N/A
Study type: Observational

Purpose of Protocol: The purpose of this study will be to compare the clinical utility of Propofol sedation with and without the use of the ICU Sedation Protocol. Patients will be treated according to the attending/consulting preference. No attempt will be made to influence the patient's routine care and management. The study will compare the average hourly infusion rates for the Propofol administration, as well as obtain the nursing staffs evaluation regarding the ease of neurological assessment during each 12 hour shift

NCT ID: NCT00594542 Completed - Anesthesia Clinical Trials

Comparison of the Total Dose and Efficacy of Two Lidocaine Concentrations Needed for Cutaneous Surgery Local Anesthesia

Start date: June 2007
Phase: N/A
Study type: Interventional

The purpose of the study will be to demonstrate whether Mohs micrographic surgery can be performed with a lower total dose of local anesthesia (and greater patient safety) when using 0.5% lidocaine with 1:200,000 epinephrine versus 1% lidocaine with 1:100,000 epinephrine.

NCT ID: NCT00564655 Terminated - Anesthesia Clinical Trials

Regional Anesthesia Block of the Transversus Abdominis Plane in Children Undergoing Gastric Tube Insertion

Start date: October 2007
Phase: Phase 3
Study type: Interventional

The objective of this trial is to examine if regional anesthetic blockade of the anterior abdominal wall via the transversus abdominis plane is a safe and feasible method of providing analgesia for children undergoing gastric tube insertion.