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Anesthesia clinical trials

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NCT ID: NCT02013882 Completed - Anesthesia Clinical Trials

1-1-12 Wash-in for Desflurane Low Flow Anesthesia

Start date: January 2014
Phase: N/A
Study type: Observational

We propose a new wash-in technique for desflurane low flow anesthesia with fresh gas flow of O2:N2O 1:1 L/min with desfluraene 12%. The objective of this study is to identify time to achieve alveolar concentration of desflurane at1, 2, 3, 4, 5 and 6%.

NCT ID: NCT02011347 Terminated - Anesthesia Clinical Trials

Ketamine and Closed-Loop Anesthesia System

LoopKeta
Start date: July 2013
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the sparing effect of ketamine on the dose of propofol.

NCT ID: NCT01998165 Completed - Anesthesia Clinical Trials

A Study to Evaluate the Safety and Efficacy of Ultiva (Remifentanil Hydrochloride) in Pediatric Participants General Anesthetised

Start date: November 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of JNJ-268229 (Ultiva /Remifentanil Hydrochloride) in pediatric participants between 1 and 15 years of age during maintenance of general anesthesia.

NCT ID: NCT01969981 Completed - Anesthesia Clinical Trials

A Study to Assess Placement and Confirmation of Peripheral Inserted Central Catheters Tip Position Using a New Electrocardiographic Method

SHERLOCK 3CG
Start date: October 2013
Phase: N/A
Study type: Observational

This is a prospective, single center, observational study. Patients who require a Peripheral Inserted Central Catheters (PICC) will constitute the study population. The purpose of the study is to determine whether Sherlock 3CG, is adequate means for the total placement of PICC and confirmation of tip of PICC placement and if this method can be conducted safely and efficiently. Patients will be included during a 6-month period as well as they are ambulatory or hospitalized. The patient's routine care will not be modified and only PICC will be assessed in the present study. PICC placement will be performed using the Site Rite guidance and tip position will be confirmed using the Sherlock 3CG. The procedure is the same as the routine habits of the operator (nurse or anesthesiologist); the vascular access team already uses the previous device for CVC placement. Patients won't be followed up in the study.

NCT ID: NCT01969903 Withdrawn - Anesthesia Clinical Trials

Study of Use of Dexmedetomidine for Regional Anesthesia

Start date: November 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out the proper amount of a drug called dexmedetomidine added to the local anesthetic drug called lidocaine to prolong the time and effect of pain relief provided for surgery. Dexmedetomidine (trade name Precedex) is approved by U.S. Food and Drug Administration (FDA) and indicated for sedation (calming effect). It has both pain relieving and calming effects when added to lidocaine. In the past, addition of higher amounts of dexmedetomidine to lidocaine decreased blood pressure and heart rate. The investigators plan to study the effect of lower amounts of dexmedetomidine to achieve the same level and duration of pain relief without reduction of blood pressure and heart rate.

NCT ID: NCT01963546 Recruiting - Diabetes Clinical Trials

Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus

Start date: March 2014
Phase: N/A
Study type: Interventional

General anesthesia can be considered as a combination of hypnosis, antinociception and immobility. Explore the effect of three kinds of anesthesia,that is the total intravenous anesthesia, inhalation anesthesia and inhalation and intravenous anesthesia on stress reactions generated by patients with diabetes conducted gastric - bypass surgery , and choose a best way from three kinds of anesthesia to control stress reaction of diabetics. After selecting the appropriate anesthesia method, assess the effect of dexmedetomidine on controlling stress response from diabetics undergoing laparoscopic gastric-bypass surgical.

NCT ID: NCT01952990 Completed - Anesthesia Clinical Trials

Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects

Start date: September 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the pharmacokinetics and safety of a nasal spray containing the anesthetic drug Tetracaine in combination with Oxymetazoline in healthy pediatric subjects.

NCT ID: NCT01948765 Completed - Clinical trials for Coronary Artery Disease

Xenon as an Adjuvant to Propofol Anaesthesia in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery.

Start date: June 2013
Phase: Phase 2
Study type: Interventional

The investigators hypothesize that the application of 30% xenon as an adjuvant to general anesthesia with a target-controlled infusion of propofol is superior to general anesthesia with propofol alone with respect to hemodynamic stability.

NCT ID: NCT01925391 Completed - Anesthesia Clinical Trials

The Measurement of Intraocular Pressure in Normal Children Under General Anesthesia With and Without Nitrous Oxide and Anesthetic Eye Drops

IOP
Start date: January 2013
Phase: Phase 0
Study type: Interventional

Pediatric glaucoma is a rare but potentially blinding condition where the pressure in the eye is too high. Diagnosis is based on intraocular pressure (IOP) and assessment of the optic nerve, cornea and other structures. Accurate intraocular pressure measurements in young children is often impossible to obtain in an office setting. Children need sedation or general anesthesia to determine IOP. All volatile general anesthetics affect the IOP. Nitrous Oxide, a weak volatile anesthetic, does not affect IOP in healthy adults. Since Nitrous Oxide has shown to be safe and effective in a variety of practice environments, we want to evaluate the use of nitrous oxide in oxygen to obtain IOP measurements in children.

NCT ID: NCT01905904 Completed - Anesthesia Clinical Trials

Sevoflurane in Electroconvulsive Therapy

Start date: March 2013
Phase: Phase 4
Study type: Interventional

The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles