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Anemia clinical trials

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NCT ID: NCT00436202 Active, not recruiting - Anemia Clinical Trials

Evaluation of an Intervention Program for the Prevention of Anemia

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether improvement in the accessibility to iron supplement will decrease anemia rates in infants.

NCT ID: NCT00337441 Active, not recruiting - Anemia Clinical Trials

Treatment of Chronic Anemia With Epoetin Alfa in Elderly

Start date: January 2003
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if chronic anemia can be corrected with epoetin alfa and does the subsequent correction lead to an improvement in fatigue,quality of life or mobility among elderly.

NCT ID: NCT00247507 Active, not recruiting - Anemia Clinical Trials

The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients

Start date: September 2005
Phase: Phase 4
Study type: Interventional

The aim of this study is to explore and identify the effects of acetylcysteine, a common mucolytic with anti-oxidant property, on alleviating the damage caused by increased oxidative stress in hemodialysis patients.

NCT ID: NCT00238043 Active, not recruiting - Clinical trials for Chronic Kidney Disease

Cohort Study to Determine the Long-Term Safety and Efficacy of Biogeneric Epoetin Treatment for Renal Anemia

Start date: August 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to establish the long-term safety and efficacy of Biogeneric Epoetin, the attainability of therapeutic target for anaemia management, and the impact of Epoetin treatment on long-term health outcome and its cost effectiveness.

NCT ID: NCT00168948 Active, not recruiting - Anemia Clinical Trials

Intermittent Antimalaria Treatment With SP in African Children

Start date: March 2003
Phase: Phase 4
Study type: Interventional

- intermittent preventive treatment with SP in children to evaluate efficacy and safety of this drug combination in children in northern Ghana

NCT ID: NCT00148629 Active, not recruiting - Anemia Clinical Trials

Treatment and Prevention of Severe Anemia in Pregnant Zanzibari Women

Start date: April 2004
Phase: Phase 3
Study type: Interventional

The purpose of this research is to compare the efficacy of two low-cost low intervention packages to prevent and treat severe anemia in pregnant women in Zanzibar, Tanzania. The two packages are Standard of Care as described by the WHO (presumptive treatment for malaria and helminths plus daily iron + folic acid supplements) and Enhanced Care (Standard of Care plus daily multivitamins and a 2nd dose of anthelminthic.)

NCT ID: NCT00061568 Active, not recruiting - Sickle Cell Disease Clinical Trials

Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias

Start date: July 16, 2004
Phase: Phase 1/Phase 2
Study type: Interventional

People with severe congenital anemias, such as sickle cell anemia and beta-thalassemia, have been cured with bone marrow transplantation (BMT). The procedure, however, is limited to children younger than the age of 16 because the risks are lower for children than for adults. The purpose of this study is to explore the use of a BMT regimen that, instead of chemotherapy, uses a low dose of radiation, combined with two immunosuppressive drugs. This type BMT procedure is described as nonmyeloablative, meaning that it does not destroy the patient s bone marrow. It is hoped that this type of BMT will be safe for patients normally excluded from the procedure because of their age and other reasons. To participate in this study, patients must be between the ages of 18 and 65 and have a sibling who is a well-matched stem-cell donor. Beyond the standard BMT protocol, study participants will undergo additional procedures. The donor will receive G-CSF by injection for five days; then his or her stem cells will be collected and frozen one month prior to BMT. Approximately one month later, the patient will be given two immune-suppressing drugs, Campath 1-H and Sirolimus, as well as a single low dose of total body irradiation and then the cells from the donor will be infused. Prior to their participation in this study, patients will undergo the following evaluations: a physical exam, blood work, breathing tests, heart-function tests, chest and sinus x-rays, and bone-marrow sampling. ...

NCT ID: NCT00039884 Active, not recruiting - Anemia Clinical Trials

Will Radiation/Chemotherapy Treatment of Cervical Cancer Work Better With Medication That May Improve Anemia?

Start date: September 2001
Phase: Phase 2
Study type: Interventional

This is a clinical trial (a type of research study) designed to describe the efficacy (effectiveness) and toxicity (safety) of a new medical treatment, NESP (Novel Erythropoiesis Stimulating Protein). This study will be offered to patients with cervical cancer undergoing a combination of chemotherapy and radiation. This treatment may lower your red blood cells. The use of NESP may stimulate the body to produce more red blood cells. Our hypothesis is that higher red blood cells will be beneficial to the patient during treatment for cervical cancer.

NCT ID: NCT00017654 Active, not recruiting - Clinical trials for Graft Versus Host Disease

Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia

Start date: April 2001
Phase: N/A
Study type: Interventional

OBJECTIVES: I. Determine the effect of supplementation with donor T-cell depleted, CD34+ peripheral blood stem cells on durable engraftment and incidence of graft-versus-host disease in patients with aplastic anemia undergoing allogeneic bone marrow transplantation.

NCT ID: NCT00006127 Active, not recruiting - Fanconi's Anemia Clinical Trials

Phase I Study of Amifostine in Patients With Bone Marrow Failure Related to Fanconi's Anemia

Start date: April 2000
Phase: Phase 1
Study type: Interventional

OBJECTIVES: I. Evaluate the toxicity of amifostine in patients with bone marrow failure related to Fanconi's anemia. II. Determine the efficacy of this treatment regimen in this patient population. III. Evaluate the effect of this treatment regimen on bone marrow progenitor cell proliferation and peripheral blood mononuclear cell apoptosis in these patients.