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Anemia, Iron Deficiency clinical trials

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NCT ID: NCT00530374 Completed - Malnutrition Clinical Trials

Impact of Sprinkles on Infectious Morbidity When Moderate to Severe Pediatric Malnutrition Is Highly Prevalent

Start date: November 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety profile of oral iron supplementation (OIS) with Sprinkles in a pediatric population with high prevalence of Iron deficiency (ID) and moderate or severe malnutrition (MSM); the efficacy profile will also be investigated.

NCT ID: NCT00520780 Completed - Clinical trials for Chronic Heart Failure

Ferinject® Assessment in Patients With Iron Deficiency and Chronic Heart Failure (FAIR-HF)

FAIR-HF
Start date: April 2007
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate the efficacy of Ferinject® in improving symptoms of CHF in patients with iron deficiency. Analyses will focus both on subjective and objective measures. Furthermore, the tolerability and safety of Ferinject® treatment will be evaluated.

NCT ID: NCT00508131 Completed - Anemia Clinical Trials

Effectiveness of Iron-Fortified Milk on Iron Status and Anemia in Young Children in Mexico

Start date: May 2003
Phase: Phase 3
Study type: Interventional

Iron deficiency and anemia in infants and young children impair neurodevelopment. Efficacious interventions for reducing the prevalences of iron deficiency and anemia, under controlled conditions, are available. However, little information is published about the effectiveness of large-scale programs. Objective. Assess the effectiveness on iron deficiency and anemia in young children of a large-scale program that provides iron fortified milk at a subsidized price to low income households. Design, Setting, and Sampling. A randomized effectiveness study in 12 milk distribution clusters randomly selected from 542 clusters in 4 States in Mexico. Selected clusters were randomly assigned to receive iron-fortified milk FM, N=7) or non-fortified milk (NFM, N=5). Over 95% program beneficiaries with children 12-30 mo of age in the 12 clusters (490 in FM and 275 in NFM) were enrolled in the FM and NFM interventions and participated in a baseline survey. 635 children (405 in FM and 230 in NFM) and 584 children (371 in FM and 213 in NFM) completed the 6 and 12-mo follow-up surveys, respectively. Intervention: A daily portion of FM contained 5.28 mg of iron, 48 mg of sodium ascorbate and other added micronutrients. The FM and NFM were distributed to beneficiaries at a subsidized price in Milk Distribution Centers in the 12 clusters. Main outcome measures: Mild-to-moderate anemia (Hb: 90-109 g/L), mild anemia (Hb: 100-109 g/L), moderate anemia (Hb: 90-99 g/L),iron deficiency: Serum Ferritin (SF) <12 ug/L and soluble transferring receptors (sTfR) >6 mg/L.Serum Zinc deficiency (< 65ug/dL), and stunting (<2SD Height/Age. Intervention effects at 6 and 12 moths were assessed using General Linear Mixed Models with three repeated measures.

NCT ID: NCT00495781 Completed - Clinical trials for Functional Iron Deficiency

Out Come Study To Define Laboratory Parameters That Are Best Suited to Diagnose Functional Iron Deficiency

SFIDS
Start date: October 2004
Phase: N/A
Study type: Interventional

The purpose of the study is to define laboratory parameters which are best suited to diagnose functional iron deficiency. Functional iron deficiency is a condition where - due to the lack of iron bioavailability - the patient suffers from symptoms such as fatigue and weakness, or his/her capacity to produce red blood cells is reduced.

NCT ID: NCT00474682 Completed - Iron Deficiency Clinical Trials

Relative Bioavailability of Ferric Pyrophosphate From an Apple Juice Drink

Start date: n/a
Phase: N/A
Study type: Interventional

The aim of this study is to find out how well iron is absorbed when a newly developed form of ferric pyrophosphate is added to a commercial apple juice drink.

NCT ID: NCT00474500 Completed - Iron Deficiency Clinical Trials

Effect of Coca-Cola on Iron Absorption

Start date: May 2007
Phase: N/A
Study type: Interventional

The aim of this project is to measure the effect of Coca-Cola and Diet Coke, relative to mineral water, on non-haem iron absorption. The results from this study will quantify any enhancing effect of Coca-Cola or Diet Coke on non-haem iron absorption and will be of use to the Coca-Cola Company and the scientific and nutrition community in evaluating the nutritional value of these products.

NCT ID: NCT00458068 Completed - Iron Deficiency Clinical Trials

Early Versus Late Enteral Iron in Infants Less Than 1301 Grams

Start date: June 1996
Phase: N/A
Study type: Interventional

Background: Preterm infants are at risk of iron deficiency. The smaller the infants are at birth, the smaller the iron stores at birth and the higher the risk of iron deficiency. Hypothesis: Preterm infants with a birth weight of less than 1301g require iron supplementation earlier than previously recommended. Methods: Prospective randomized controlled clinical trial (1996-1999). Results: Early iron supplementation may reduce the incidence of iron deficiency and the need for late blood transfusions.

NCT ID: NCT00457990 Completed - Iron Deficiency Clinical Trials

Neurodevelopment After Early Iron Supplementation

Start date: April 2002
Phase: N/A
Study type: Interventional

Background: Iron deficiency in early childhood may impair neurodevelopment. Aim: To examine whether early iron supplementation improved neurodevelopment in preterm infants. Method: Children who participated in a clinical trial of iron supplementation were invited for a neurodevelopmental follow-up examination at the time of school entry.

NCT ID: NCT00456729 Completed - Iron Deficiency Clinical Trials

Malabsorption as a Cause of Iron Treatment Failure in Infants

Start date: May 2006
Phase: N/A
Study type: Interventional

Infants should receive prophylacatic iron supplementation since age 4 months till one year. Patients suffering from malabsorption, mainly Giardia infestation may develop iron deficiency resistent to further iron treatment. The purpose of this study is to assess the incidence of malabsorption in those infants and to examine the results of empiric treatment with metronidazole.

NCT ID: NCT00414479 Completed - Malaria Clinical Trials

Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment

Start date: July 2006
Phase: N/A
Study type: Observational

The purpose of this study is to determine the extend and the nature of anemia in school children and the correlation between anemia and schistosomiasis infections, malaria infections and/or malnutrition (iron deficiency).