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Analgesia clinical trials

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NCT ID: NCT04877574 Completed - Surgery Clinical Trials

ANI-guided Intraoperative Analgesia vs Conventional Intraoperative Analgesia

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

This study evaluates the effects of Analgesia Nociception Index (ANI)-guided intraoperative analgesia on postoperative pain in patients undergoing open gynecologic surgery.

NCT ID: NCT04875039 Completed - Analgesia Clinical Trials

Dexametasone Versus Dexametasone Plus Dexmedetomidine in Nerve Blocks

Start date: August 31, 2021
Phase: Phase 4
Study type: Interventional

This study will compare perineural dexamethasone 2mg and perineural mixture of dexamethasone 2mg plus dexmedetomidine 50mcg DX plus DXD as adjuvants to local anesthetics for ultrasound-guided infraclavicular brachial plexus blocks (ICBs). The protocol is designed as a superiority trial and hypothesizes that the mixture of both drugs results in longer block duration. Furthermore, since analgesic and sensory duration can be influenced by the intake of pain medications and surgical trauma to small cutaneous nerves, respectively, motor block duration was selected as the main outcome to better target the action of both adjuvants on the brachial plexus.

NCT ID: NCT04858984 Completed - Pain Clinical Trials

Virtual Reality, Experience During Labour; a Qualitative Research (VIREL)

VIREL
Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Childbirth is associated with labour pain and can be regarded as one of the most serious kinds of pain. Labour pain management methods include pharmacological and non-pharmacological methods. There is increasing evidence that virtual reality (VR) is effective in the reduction of labour pain. The aim of this qualitative study is to explore the experience, preference, and satisfaction of the use of two different VR scenario's during labour. The secondary outcome parameter is the effect of VR on pain reduction and anxiety during labour, measured by NRS score.

NCT ID: NCT04854395 Completed - Analgesia Clinical Trials

Femoral Triangle Block With Popliteal Plexus Block Versus Femoral Triangle Block Versus Adductor Canal Block for TKA

Start date: April 9, 2021
Phase: Phase 4
Study type: Interventional

In this study we wish to investigate the analgesic effect 3 different nerve block regimes in patients following primary total knee arthroplasty (TKA). All nerve blocks were performed as single shot blocks with the administration of Marcain 5 mg/ml. Regime A: proximal Femoral Triangle Block (FTB) with 10 ml including Intermediate Femoral Cutaneous Nerve Block (IFCNB) with 5 ml + Popliteal Plexus Block (PPB) with 10 ml. Regime B: proximal FTB with 10 ml including IFCNB with 5 ml. Regime C: Adductor Canal Block (ACB) with 25 ml.

NCT ID: NCT04835415 Completed - Analgesia Clinical Trials

Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate analgesic effect of ultrasound-guided retrolaminar block vs ultrasound-guided thoracic epidural analgesia in pain control following laparoscopic cholecystectomy.

NCT ID: NCT04814537 Completed - Analgesia Clinical Trials

Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques

Start date: February 25, 2021
Phase: Phase 4
Study type: Interventional

To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.

NCT ID: NCT04813016 Completed - Analgesia Clinical Trials

Intraperitoneal Tramadol Versus Dexmedetomedine for Analgesia After Abdominal Laparoscopic Cancer Surgeries

Start date: March 1, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Multiple modalities for postoperative analgesia after laparoscopic procedures has been used, of them intraperitoneal route (IP) was used to decrease the analgesic requirements. Both early and late bupivacaine and tramadol versus bupivacaine and dexmedetomedine will be tried to choose which is having a better analgesic profile.

NCT ID: NCT04800302 Completed - Surgery Clinical Trials

U/S-guided Continuous Quadratus Lumborum Block III in Percutaneous Nephrolithotomy

Start date: June 10, 2021
Phase: N/A
Study type: Interventional

Percutaneous nephrolithotomy (PCNL) is considered to be the first choice and a more conservative procedure than open stone surgery. Not only postoperative pain related to dilatation of the renal capsule and parenchymal tract, but also patient's discomfort & nephrostomy tube-related stress are reported to delay recovery time and increase the complication rates. This study is designed to provide postoperative analgesia by using ultrasound-guided continuous Quadratus Lumborum Block (QLB) III in patients undergoing PCNL and to assess pain scores & side effects with less opioids consumption.

NCT ID: NCT04796363 Completed - Breast Cancer Clinical Trials

US Guided Erector Spinae Plane Block in Breast Cancer Surgery: Analgesia, Spread and Immunomodulation

Start date: November 25, 2020
Phase: N/A
Study type: Interventional

Prospective interventional study

NCT ID: NCT04763876 Completed - Analgesia Clinical Trials

Intramuscular Ketorolac at Two Single-Dose Regimens

Start date: June 27, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate a single 15 mg intramuscular (IM) dose of ketorolac for analgesic non-inferiority versus a single 60 mg IM dose for the treatment of acute MSK pain in a military emergency department (ED) that services Department of Defense (DoD), Department of Veteran Affairs (VA), and foreign military beneficiaries