Novel Intervention for Amphetamine-type Stimulants Addiction

Status Completed

Clinical Trial Summary

The repetitive transcranial magnetic stimulation (rTMS) will be used to treat amphetamine-type stimulant (ATS) addiction.

Clinical Trial Description

The Glutamate and GABA deficits in prefrontal cortex play a vital role in ATS addiction and relapse, and proposed repetitive transcranial magnetic stimulation (rTMS) as a novel interventions. Focused on evaluating Glutamate/GABA functions in prefrontal cortex and functional connectivity with deep brain regions, neuropsychological tests, biochemical tests, magnetic resonance spectroscopy (MRS) and functional MRI will be used to investigate the neurobiological mechanism of ATS addiction and relapse. These methods will also be used to evaluate the efficacy of the novel intervention and investigate the mechanisms. The study will be very helpful to develop novel interventions in clinical practice and decrease ATS-related harm for both the patients and their families. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02713815
Study type	Interventional
Source	Shanghai Mental Health Center
Contact
Status	Completed
Phase	N/A
Start date	July 2016
Completion date	July 2019

View Details

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