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Clinical Trial Summary

The computerized cognitive rehabilitation therapy will be used to treat amphetamine-type stimulant (ATS) addiction.

Clinical Trial Description

The deficits in executive functions related to prefrontal-striatal circuits play a vital role in ATS addiction and relapse, and proposed computerized cognitive rehabilitation therapy as the novel interventions. Focused on evaluating and training executive functions including working memory, inhibitory control, cognitive flexibility, and congitive bias concerning prefrontal-striatal circuits, neuropsychological tests, electroencephalography tests, magnetic resonance spectroscopy (MRS) and functional MRI will be used to evaluate the therapeutic effect of ATS addiction treatment as well as investigate the mechanisms. The study will be very helpful to develop novel interventions in clinical practice and decrease ATS-related harm for both the patients and their families. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT03318081
Study type Interventional
Source Shanghai Mental Health Center
Contact Zhao Min, PhD, MD
Phone 021-54252689
Status Recruiting
Phase N/A
Start date October 20, 2017
Completion date January 31, 2018