Cannabioids as a New Intervention for Amphetamine Dependence

Status Withdrawn

Clinical Trial Summary

Addiction to amphetamine is characterized by alternating phases of intoxication and short abstinence, followed by recurrent drug-craving episodes which result in distress and relapse. Addiction involves a number of neurotransmission systems, including the endocannabinoid system (ECBS). It has been demonstarted that cannabidioids can have physiological, anxiolytic and neuroprotective properties. It has been shown to have multiple therapeutic properties for treating anxiety, schizophrenia and interestingly cannabinoids have been shown to be potentially helpful in treating addiction, due to their effects on various neuronal circuits involved in this disorder. The investigators overall hypothesis is that cannabinoids are an interesting pharmacological contender to decrease amphetamine craving and treat amphetamine addiction.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02952196
Study type	Interventional
Source	Centre hospitalier de l'Université de Montréal (CHUM)
Contact
Status	Withdrawn
Phase	Phase 2
Start date	November 2016
Completion date	December 2017

View Details

See also
Status	Clinical Trial	Phase
Not yet recruiting	`NCT05535101` - Non-invasive Brain Stimulation in Patients With Methamphetamine Use Disorder	N/A
Not yet recruiting	`NCT02836756` - Cannabidiol as a New Intervention for Amphetamine Dependence	Phase 2
Completed	`NCT03318081` - The Application of Cognitive Rehabilitation Therapy for Amphetamine-type Stimulants Addiction	N/A
Completed	`NCT03221283` - The Application of Music Therapy in Female Amphetamine Use Disorder	N/A
Completed	`NCT02285556` - The Diagnostic Assessment and Intervention Study of Amphetamine Type Stimulus	N/A
Completed	`NCT02713815` - Novel Intervention for Amphetamine-type Stimulants Addiction	N/A
Completed	`NCT00713479` - An Assessment of the Safety of Varenicline in Methamphetamine-dependent Volunteers	Phase 1
Completed	`NCT04993300` - Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction	N/A
Completed	`NCT02950376` - The Novel Addiction Assessment Study in Synthetic Drugs Addiction
Recruiting	`NCT04531384` - Robot-Assisted Intelligent Rehabilitation Treatment for Methamphetamine Use Disorders.	N/A
Recruiting	`NCT04687566` - Dextromethorphan, Memantine Monotherapy, or Combined Use of Dextromethorphan and Memantine in Amphetamine Addiction	Phase 2/Phase 3