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Agoraphobia clinical trials

View clinical trials related to Agoraphobia.

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NCT ID: NCT03113175 Completed - Clinical trials for Post Traumatic Stress Disorder

Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice

Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The aim of the study Collabri Flex is to: - Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project. - Examine the impact of this model compared with liaison-consultation for people with anxiety in a randomized controlled design from selected endpoints.

NCT ID: NCT03101332 Completed - Panic; Agoraphobia Clinical Trials

Virtual Reality for Panic Disorder With Agoraphobia

Start date: May 1, 2017
Phase: N/A
Study type: Interventional

Panic disorder with agoraphobia (PDA) is associated with considerable personal distress, functional disability and societal costs. A large number of studies have shown that Cognitive Behavior Therapy (CBT) is a highly effective treatment for PDA. However, the CBT-protocols proven to be most effective involves repeated exposure to the particular environments the agoraphobic patient fears such as trains, tunnels, lifts and shops. This cause great practical problems for health care services as such therapeutic efforts involves spending considerable time outside the clinic. For primary care services this is particularly challenging due to the large number of patients expected to be seen. Normally clinicians meet up to 7 patients daily which makes it almost practically impossible to offer 2-hour sessions, which is necessary to carry out the relevant exposure tasks. Hence, the treatment proven to be most effective, which primary care services are commissioned to deliver, is too comprehensive and time consuming to be applied in real practice. The investigators believe that a possible solution to the above problem is to provide evidence-based CBT but with the exposure components carried out through Virtual Reality (VR) rather than in vivo. Some research has already been done with virtual reality and exposure therapy for anxiety disorders with promising results. The aim of this pilot study is to treat patients with agoraphobia with or with a history of panic disorder with a standardized exposure-based CBT-protocol through VR. The virtual environments that are used for the study are live sequences filmed in 360°. The investigators hypothesize that CBT with VR will be effective and lead to improvements on measures of panic disorder and agoraphobia.

NCT ID: NCT03061448 Completed - Clinical trials for Panic Disorder With Agoraphobia

Internet-based Exposure Therapy for Panic Disorder

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is examine if an internet-based exposure therapy based on inhibitory learning is feasible, acceptable and effective in reducing panic symptoms amongst patients who suffer from panic disorder and agoraphobia.

NCT ID: NCT03051074 Completed - Clinical trials for Major Depressive Disorder

Examining the Effects of Reduced Environmental Stimulation on Anxiety

Start date: December 1, 2016
Phase: N/A
Study type: Interventional

The studies proposed in this protocol aim to explore the anxiolytic properties of floating as it relates to the central and autonomic nervous system.

NCT ID: NCT02954731 Completed - Panic Disorder Clinical Trials

Trans-diagnostic Group CBT vs. Standard Group CBT for Depression, Social Anxiety and Agoraphobia/Panic Disorder

TRACT-RCT
Start date: December 2016
Phase: N/A
Study type: Interventional

Transdiagnostic Cognitive Behavior Therapy (CBT) delivered in the individual format, have been proven just as effective as traditional diagnosis specific CBT manuals. The investigators have translated and modified the "The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders" (UP-CBT) to make it applicable as group therapy in Danish Mental Health Service and a naturalistic trial of this manual has shown promising results. As the use of one manual instead of several diagnosis specific manuals in regional clinics could simplify logistics and reduce waiting time, the investigators want to compare group UP-CBT with diagnosis specific group CBT. Method: A partial blinded, pragmatic, non-inferiority, multicentre randomized clinical trial (RCT). UP-CBT is compared to treatment-as-usual CT. 124 patients are included in each intervention arm, recruited from three Danish regional Mental Health Service Clinics. 31st July 2018 suppl: Inclusion number expanded to 170 in each arm due to unexpected large drop-out.

NCT ID: NCT02852577 Completed - Panic Disorder Clinical Trials

Long Term Treatment of Panic Disorder With Clonazepam or Paroxetine

LTTPANIC
Start date: January 2000
Phase: Phase 4
Study type: Interventional

The purpose of this study was to determine whether clonazepam and paroxetine are effective in the treatment of panic disorder. Efficacy was evaluated in short-term, long-term and post-treatment.

NCT ID: NCT02811458 Completed - Clinical trials for Generalized Anxiety Disorder

Clinical Trial of Transdiagnostic Cognitive-Behavior Therapy for Anxiety Disorders

T-CBT
Start date: September 12, 2016
Phase: N/A
Study type: Interventional

Anxiety disorders are the most common mental disorders in community settings, and they are associated with significant psychological distress, functional and social impairment. Although pharmacological and psychological treatments for anxiety and depression have existed for several years now, only a minority of anxiety disorder sufferers are treated according to guidelines. Cognitive behavior therapy (CBT) is the most consistently efficacious psychological treatment for anxiety disorders, but implementation of CBT in primary care is challenging due to limited resources. Recent studies indicate that transdiagnostic group CBT for multiple anxiety disorders could be a promising alternative to individual CBT in primary care. The aim of the study is to examine the effectiveness of group CBT for anxiety disorders as a complement to usual care. The clinical trial will be conducted in three Health and Social Services Centers in the province of Québec (i.e. Sherbrooke, Laval and Québec). Patients will be French-speaking adults with anxiety disorders, and they will be randomly assigned to one of two treatment conditions: a) Transdiagnostic group CBT (12 weekly 2-hour sessions), b) usual care. The transdiagnostic group CBT will be offered as a differed intervention to participants in the usual care group after the 8-month follow up. Participants in both study arms will undergo a baseline clinical evaluation as well as outcome assessment interviews at post-treatment, 4, 8, and 12 month follow-up time-points. The primary study results will include improvement on a questionnaire on anxiety symptoms. Widespread implementation of group CBT could lead to better outcomes for a large number of patients living with anxiety.

NCT ID: NCT02810171 Completed - Anxiety Clinical Trials

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety

Anxiety-CBT
Start date: December 2016
Phase: N/A
Study type: Interventional

Anxiety is among the most prevalent, costly and disabling illnesses and tends emerge early in childhood. Cognitive behavioral therapy (CBT) is the first-line treatment for early life anxiety, but as many as 40% of young patients who receive CBT fail to get better. The proposed study will examine brain changes marking positive response to CBT for anxiety and how these changes may differ in children compared adolescents. By helping us to understand how CBT works, this study will pave the way for new treatments to stop anxiety early.

NCT ID: NCT02605668 Completed - Panic Disorder Clinical Trials

Providing Tools for Effective Care and Treatment of Anxiety Disorders

PROTECT-AD
Start date: December 12, 2015
Phase: N/A
Study type: Interventional

PROTECT-AD is a cognitive behavioral treatment study involving highly qualified psychotherapeutic centers at seven German universities. It is our goal to further investigate and optimize existing effective treatments of anxiety disorders. In order to achieve this, the investigators want to investigate the effect of extinction learning in an "intensified" psychological intervention on treatment outcome in adults and children with anxiety disorders. The intensified psychological intervention is characterized by a higher number of exposure trials over a short time period. In the control condition the exposure trials take place in a weekly interval, analog to standard care.

NCT ID: NCT02305537 Recruiting - Clinical trials for Obsessive-Compulsive Disorder

Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment

Start date: October 2014
Phase: N/A
Study type: Interventional

The collection of patient self-report and diagnostic data will allow us to examine the efficacy of the treatment delivered in the McLean Anxiety Mastery Program. Using data gathered through routine clinical care, the investigators seek to explore whether patients in treatment show improvements from admission to discharge, compared to patients on the waitlist, and whether these gains are maintained three months post-discharge. The following are included as examples of some of the study's hypotheses.