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Acute Renal Failure clinical trials

View clinical trials related to Acute Renal Failure.

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NCT ID: NCT02064244 Completed - Acute Renal Failure Clinical Trials

Inferior Vena Cava (IVC) Size in Acute Renal Failure

Start date: February 2014
Phase: N/A
Study type: Observational

Bedside ultrasonographic assessment of IVC size and IVC collapsibility index can be used to guide the management of patients with acute kidney injury with and without volume overload in the intensive care unit

NCT ID: NCT02055430 Completed - Children Clinical Trials

Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage

Start date: March 2010
Phase: N/A
Study type: Interventional

To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children

NCT ID: NCT01979042 Completed - Acute Renal Failure Clinical Trials

Urinary Markers for Unilateral Kidney Obstruction

Start date: October 2013
Phase: N/A
Study type: Observational

Renal colic is usually caused from an obstructing stone along the ureter. Some of the patients present with a high level of creatinin in the blood, even though there is a normal functioning contralateral kidney. Furthermore creatinin is not an ideal marker for renal function during acute changes. Several works have shown that modern urinary markers such as NGAL (neutrophil gelatinase-associated lipocalin), KIM-1 (Kidney Injury Molecule-1) and others rise earlier and are much more sensitive for kidney insult. There is a lack of research on their role in acute kidney obstruction

NCT ID: NCT01946113 Completed - Acute Renal Failure Clinical Trials

Mineral-Homeostasis in Continuous Renal Replacement Therapy

Start date: September 2013
Phase: N/A
Study type: Observational

Acute renal failure is a common complication in intensive care unit patients. In 10% of cases renal replacement therapy becomes necessary. Current devices have increase filter patency and efficacy. However, magnesium, calcium and phosphate are eliminated as well. However, the extend of this elimination hase not been quantified. Thus, we want to 1. record retrospectively how often abnormal values for phosphate, magnesium and calcium occurred during routine renal replacement therapy in 2011 and 2012. 2. prospectively evaluate the same parameters during routine treatment in 2013 and 2014

NCT ID: NCT01941823 Completed - Acute Renal Failure Clinical Trials

Carnitine, Aclycarnitine, Myocardial Function, and CRRT

Start date: December 2014
Phase:
Study type: Observational

Carnitine is essential for the transport of fatty acids into the mitochondria and energy production in different muscles, including the myocardium. It is also needed to protect myocyte cell membranes from oxidative damage by removing excess acyl carnitine groups. Patients receiving chronic intermittent hemodialysis (HD) are known to be at increased risk for carnitine deficiency as a result of its removal during the dialysis procedure, lack of endogenous synthesis by the kidney, and inadequate dietary intake. The carnitine status of children undergoing continuous renal replacement therapy (CRRT) has not been studied. Children undergoing CRRT in the intensive care unit (ICU) setting may be at increased risk for carnitine deficiency due to its continuous removal, lack of carnitine production by the kidney, and absence of carnitine intake (as majority of these children can not eat and there is no carnitine added to total parenteral nutrition (TPN). Carnitine deficiency may increase the risk of cardiac dysfunction in critically ill children. This is the first study to examine carnitine status in children undergoing CRRT. Standard echo as well as more sensitive speckle tracking echo will be used to evaluate the effect of carnitine deficiency on myocardial function.

NCT ID: NCT01907061 Completed - Acute Renal Failure Clinical Trials

Acute Renal Failure Post Liver Transplantation

Start date: July 2007
Phase: N/A
Study type: Interventional

Trial to test the effect of administering N-acetylcysteine on cytokines and markers of oxidant stress and the incidence of acute renal failure post liver tranplant

NCT ID: NCT01878968 Completed - Stroke Clinical Trials

Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?

Start date: April 2013
Phase: N/A
Study type: Interventional

There is evidence to suggest that patients make different end-of-life decisions if they understand the risks, benefits and alternatives of CPR and mechanical ventilation. This study will examine whether evidence-based informed consent impacts patients choices and healthcare outcomes compared to routine care.

NCT ID: NCT01866397 Completed - Acute Renal Failure Clinical Trials

Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration

Start date: March 2002
Phase: Phase 4
Study type: Interventional

Cidofovir is an acyclic nucleotide analog with broad-spectrum antiviral activity against herpesviruses. Its potency in inhibiting HCMV has been shown in conventional in vitro studies. It is approved for the systemic treatment of human cytomegalovirus (HCMV) retinitis in patients with AIDS and as a second line therapy for HCMV infections not responding to ganciclovir or foscarnet. In intensive care patients continuous venovenous haemofiltration (CVVH) is a well-established extracorporal renal replacement therapy with a high clearance rate. Pharmacokinetic studies of antifungal agents in critically ill patients treated with CVVH are rare. Elimination of any given drug by renal replacement therapy is determined by several major factors which are membrane specific, due to physico-chemical properties of the drug and characteristics of the renal replacement technique used. Study objective The trial is conducted to investigate the pharmacokinetics of cidofovir during CVVH in critically ill patients. It is suspected that Hemofiltration will influence cidofovir plasma levels.

NCT ID: NCT01819038 Completed - Acute Renal Failure Clinical Trials

Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury

EarlyRRT
Start date: January 2013
Phase: N/A
Study type: Interventional

This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in decision- making.

NCT ID: NCT01753024 Completed - Diabetes Clinical Trials

Pancreatic Exocrine Insufficiency and Pancreatic Enzyme Supplementation in Critically Ill Adult Patients

Start date: January 2012
Phase:
Study type: Observational [Patient Registry]

Malnutrition is a frequent problem in critically ill patients that is associated with detrimental clinical outcomes. To provide adequate nutritional support, current studies focused mostly on the choice of delivery timing, formula selection and the route of administration, little attention was paid to malnutrition related to exocrine pancreatic insufficiency (EPI). In fact, malnutrition is also a major consequence of pancreatic exocrine insufficiency and pancreatic damage is commonly observed in critically ill patients without prior pancreatic diseases. Hence, EPI associated malnutrition should be concerned due to the high prevalence of pancreatic damage in critically ill patients. The aims of this study is to evaluate the incidence of EPI in critically ill adult patients and explore its potential risk factors. Moreover, the efficacy of pancreatic enzyme supplementation therapy on malnutrition in ICU patients with specific clinical characteristics will be investigated.