Hydration Status Assessment Through Body Composition Monitoring in

Status Recruiting

Clinical Trial Summary

Aims:

- evaluate the hydric status through bioimpedance spectroscopy in consecutive acute myocardial infarction patients referred for primary PCI;

- assessment of renal artery stenosis incidence through renal angiography in consecutive STEMI patients;

- fully characterize the complex hydration, metabolic and endothelial profile of these patients in the attempt to define the role played by dehydration in the complex dynamics of acute myocardial infarction.

Clinical Trial Description

Gathered data:

- descriptive general demographic data;

- previous pathologies (ischemic heart disease, peripheral arterial disease, stroke, heart failure, previous percutaneous coronary interventions, coronary artery bypass grafting - CABG, known renal disease);

- cardiovascular risk factors (age, weight, height, abdominal perimeter, body mass index, smoking, sedentariness, diabetes, hypertension, dyslipidaemia);

- routine biological data;

- metabolic data (obtained from two body composition monitoring evaluations - before and 12 hours after coronary intervention) - body water, body fat tissue;

- information regarding primary PCI (less than 12 hours of ischemic symptoms);

- coronarographic details, type of used stent, periprocedural specific complications, final TIMI - thrombolysis in myocardial infarction - flow);

- echocardiography at admission (LVEF);

- renal arteries angiographic details performed in the same time with PCI (two independent operators evaluate stenosis based on a predefined scale);

- renal diameters;

- measurement of arterial stiffness through Sphigmocore pulsed-wave-velocity (24 hrs post-procedural, 2 velocities: carotid - femoral and carotid - radial);

- in-hospital and one month follow-up MACE. ;

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02655341
Study type	Observational
Source	Grigore T. Popa University of Medicine and Pharmacy
Contact	Alexandru Burlacu, M.D.
Phone	0040744488580
Email	alburlacu@yahoo.com
Status	Recruiting
Phase	N/A
Start date	January 2016
Completion date	January 2018

View Details

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Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Hydration Status Assessment Through Body Composition Monitoring in Patients With Acute Myocardial Infarction — HYD-AMI

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms