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Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response — COLIN  

Acute Myocardial Infarction Clinical Trial

Official title:
Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response

Clinical Trial Summary

Background:

Colchicine is an old well-known venerable drug routinely used in gout attacks for instance.

More recnetly it is regularly use in the treatment of pericarditis. It couls exert antiiflammatory effects targeting the adverse inflammation occuring incase of acute myocardial infarction, which is involved in poor outcomes or longer stay at hospital.

Endpoints:

- Main endpoint: AUC CRP during the initial hospital stay

- Secondary endpoints:

- Clinical: oucomes

- Imaging: ETT, MRI

- Biological: various biomarkers

Method Randomized, controled, open-labbelled, comparing two parallel arms: conventionnal optimal treatment versus conventionnal optimal treatment + colchicine

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02363725
Study type Interventional
Source University Hospital, Montpellier
Contact
Status Completed
Phase Phase 2
Start date December 2014
Completion date August 2016
View Details
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