Acute Myocardial Infarction Clinical Trial
Official title:
Randomised Controlled Clinical Trial of the Use of Autologous Bone Marrow Derived Progenitor Cells to Salvage Myocardium in Patients With Acute Anterior Myocardial Infarction
Study hypothesis :
The purpose of this study is to determine whether Intracoronary infusion of autologous bone
marrow derived progenitor cells to patients undergoing primary angioplasty for acute anterior
myocardial infarction will lead to an improvement in cardiac function greater than that seen
by placebo alone.
Aims
- To demonstrate that it is safe and feasible to deliver autologous bone marrow derived
stem cells within hours of the primary angioplasty procedure
- To demonstrate the effects of autologous bone marrow derived stem cells on cardiac
function using cardiac MRI (or cardiac CT), echocardiography and left ventriculography.
- To demonstrate the effect of autologous bone marrow derived stem cells in addition to
standard care leads to improvement in cardiac function compared to patients
saline(placebo) and standard care.
n/a
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