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Clinical Trial Summary

This is an open-label, multicenter, dose-escalation Phase 1/1b study in patients with acute myelogenous leukemia (AML)/MDS or non-Hodgkin Lymphoma (NHL), intended to investigate safety, pharmacokinetics, and the pharmacodynamic effects of FT-1101 administered via one or more intermittent dosing schedules alone and in combination with azacitidine. Once the MTD has been established for a treatment cohort, up to 20 additional patients may be enrolled in up to 4 expansion cohorts each of select populations of patients with either AML/MDS or NHL at the recommended dose for future studies to confirm safety.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02543879
Study type Interventional
Source Forma Therapeutics, Inc.
Contact Lindsey Wilson
Email lwilson@formatherapeutics.com
Status Recruiting
Phase Phase 1
Start date September 2015
Completion date October 2019

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