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Prognostic Markers of Post-Stroke Depression (PROMoSD) — PROMoSD  

Acute Ischemic Stroke Clinical Trial

Official title:
Prognostic Markers of Post-Stroke Depression: A Single-center Prospective Observational Study

Clinical Trial Summary

Single-center prospective observational study investigating the association of brainstem raphe hypoechogenicity detected by transcranial sonography and post-stroke depression three months after an acute ischemic stroke.

Clinical Trial Description

Post-stroke depression (PSD) is an important complication after a stroke. Despite significant limitations between studies of PSD risk factors, stroke severity or post-stroke disability, prior depressive episodes, and female sex are arguably the most well-known risk factors for developing PSD, although the predictive value of these factors is limited. A hypoechogenic brainstem raphe (BR) detected by transcranial sonography (TCS) is associated with depressive symptoms in distinct diseases but is also common with approximately 25% of the non-depressed population in Europe. The primary aim of this study is to investigate the association between BR hypoechogenicity and PSD occurrence in a prospective observational study design. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05580198
Study type Observational
Source Ruhr University of Bochum
Contact Daniel Richter, Dr,
Phone 00492345090
Email daniel.richter-c34@rub.de
Status Recruiting
Phase
Start date January 1, 2021
Completion date March 2023
View Details
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