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Clinical Trial Summary

This study compares the success rate of Adjuvant isonicotinic acid hydrazide and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy among women with one or more previous cesarean deliveries.


Clinical Trial Description

In the past, the role of laminaria and prostaglandins in cervical dilatation and reducing intraoperative complications of cervical dilatation have been proven . Misoprostol is a synthetic analogue of prostaglandin E1 used to treat and prevent gastric ulcers, which is now widely used in obstetrics and gynecology. Its applications in obstetrics and gynecology include medical abortion in the first and second trimesters of pregnancy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04499976
Study type Interventional
Source Aswan University Hospital
Contact hany f Sallam, md
Phone +20102435461
Email hany.farouk@aswu.edu.eg
Status Not yet recruiting
Phase Phase 4
Start date September 1, 2020
Completion date June 30, 2021

See also
  Status Clinical Trial Phase
Active, not recruiting NCT03736681 - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage Phase 1
Completed NCT03636451 - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o Phase 3
Recruiting NCT05124314 - Comparison of Two Different Drug Regimens for Medical Treatment of Early Pregnancy Loss Phase 4
Recruiting NCT02917785 - Testing the Efficiency of Karman Curette in the Treatment of Misoprostol Failure in Women With Missed Abortion N/A
Completed NCT04906278 - Amniotomy for Second-trimester Pregnancy Termination N/A
Completed NCT03148314 - Vaginal Misoprostol In Management Of First Trimester Missed Abortion. Phase 2
Not yet recruiting NCT03799081 - Use of Fetoscopy in Missed Abortion N/A
Completed NCT00784797 - Misopristol Versus Pitocin for Second Trimester Abortion Phase 4
Completed NCT03767179 - Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases
Completed NCT02515604 - Comparison of Single and Repeated Dose of Vaginal Misoprostol for the Treatment of Early Pregnancy Failure Phase 4
Completed NCT00410345 - Cervical Rippening With Antiprogesterone in Midtrimester Abortions Phase 4