Clinical Trials Logo

Clinical Trial Summary

Induction of midtrimester abortion includes cervical ripening and then contraction to induce uterine evacuation. There are several protocols, but most of them include using prostaglandins (PG). The disadvantages of using PG include uncomfortable side effects and limits of using it for women after cesarean section. Mifepristone is an antiprogesterone drug and been used for induction of abortion in first and second trimesters abortions. The aim of this study is to explore the effectiveness of Mifepristone for cervical ripening before high dose Oxytocin drip.


Clinical Trial Description

The aim of this study is to explore the effectiveness of Mifepristone for cervical ripening before high dose Oxytocin drip in midtrimester abortions. After informed consent, all the women will be randomized for Mifepristone or placebo. 48 hours later, high dose oxytocin drip will be started and we will examine the success rate to induce abortion, the duration from starting oxytocin till evacuation of uterus and side effects. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00410345
Study type Interventional
Source Hadassah Medical Organization
Contact
Status Completed
Phase Phase 4
Start date August 2004
Completion date May 2008

See also
  Status Clinical Trial Phase
Not yet recruiting NCT04499976 - Isonicotinic Acid Hydrazide Pretreatment With Misoprostol Induction of Abortion in First-trimester Missed Miscarriage Phase 4
Active, not recruiting NCT03736681 - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage Phase 1
Completed NCT03636451 - Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage.o Phase 3
Recruiting NCT05124314 - Comparison of Two Different Drug Regimens for Medical Treatment of Early Pregnancy Loss Phase 4
Recruiting NCT02917785 - Testing the Efficiency of Karman Curette in the Treatment of Misoprostol Failure in Women With Missed Abortion N/A
Completed NCT04906278 - Amniotomy for Second-trimester Pregnancy Termination N/A
Completed NCT03148314 - Vaginal Misoprostol In Management Of First Trimester Missed Abortion. Phase 2
Not yet recruiting NCT03799081 - Use of Fetoscopy in Missed Abortion N/A
Completed NCT00784797 - Misopristol Versus Pitocin for Second Trimester Abortion Phase 4
Completed NCT03767179 - Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases
Completed NCT02515604 - Comparison of Single and Repeated Dose of Vaginal Misoprostol for the Treatment of Early Pregnancy Failure Phase 4