Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases

Abortion, Missed Clinical Trial

Official title:

Research of Serum Procalcitonin, Erythrocyte Sedimentation Rate, C-Reactive Protein And Leukocyte Levels in Fertile Missed Abortion Cases

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03767179
• Other study ID #: KTU
• Status: Completed
• Start date: January 1, 2018
• Est. completion date: May 15, 2018

Study information

• Verified date: June 2020
• Source: Karadeniz Technical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

Description:

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: May 15, 2018
• Est. primary completion date: April 15, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

Exclusion Criteria:

• Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus)

• Smoking

• Rejection to participate in the study.

Related Conditions & MeSH terms

• Abortion, Missed

Intervention

Diagnostic Test:
• study
procalcitonin, sedimentation, CRP, leukocyte identification

Locations

Country	Name	City	State
Turkey	Karadeniz Technical University, Medical Faculty of Medicine.	Trabzon	Ortahisar

Sponsors (1)

Lead Sponsor	Collaborator
Karadeniz Technical University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Serum LC	Serum leukocyte count in number	01.01.2018- 15.02.2019
Primary	CRP	Serum CRP level in microgram	01.01.2018- 15.02.2019
Primary	ESR	Erythrocyte sedimentation rate	01.01.2018- 15.02.2019
Primary	Prokalsitonin	Serum procalcitonin level in microgram	01.01.2018- 15.02.2019