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Abortion Early clinical trials

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NCT ID: NCT03736681 Recruiting - Clinical trials for Abortion, Spontaneous

Effect of Paracervical Block Volume on Pain Control for Dilation and Curettage

Start date: October 29, 2018
Phase: Phase 1
Study type: Interventional

We are conducting a study on pain control for D&C. You are eligible to participate if you are a planning to have a D&C in our clinic. We are studying how different ratios of medication to liquid affect pain when injected around the cervix. Both potential methods use the same dose of medication, though we would like to know which one works better. To be in this study you must be over the age of 18 with an early pregnancy loss or undesired pregnancy measuring less than 12 weeks gestation undergoing D&C while awake in clinic.

NCT ID: NCT03417362 Recruiting - Clinical trials for Abortion in First Trimester

Delivery of Audiovisual Information on Early Medical Abortion

Start date: March 5, 2018
Phase: N/A
Study type: Interventional

The majority of abortions in the United Kingdom (UK) are performed before 9 weeks (63 days) gestation using a method known as Early Medical Abortion (EMA). EMA involves an assessment visit and provision of two types of medication . The assessment visit usually involves Ultrasound to confirm gestation, detailed personal history, safeguarding assessment and contraception planning, before arranging treatment and follow up. The process is long and lots of information is given to women attending the service. In NHS Lothian (National Health Service, Lothian Health Board), the average appointment length for combined assessment and provision of the first part of treatment is 3 hours. Despite how common abortion is ( 1 in 3), many women presenting for abortion care are not aware of what the procedure will involve. This may in part to the social stigma surrounding abortion and unintended pregnancy in general. This stigma can in turn result in feelings of anxiety and shame about the decision to terminate a pregnancy. There is evidence that short videos shown to patients prior to abortion or contraception consultations can improve their ability to recall information and can make them feel more confident about the procedure. Additionally, abortion care providers have found patients who have seen videos to be better prepared and informed and this allows consultations to progress more easily and allow greater time for discussion of contraceptive methods. We have prepared a video approximately 3 minutes in length to provide information about EMA. It summarises the process described above using simple language and animated characters. The video has been translated into French, Portuguese and Swedish and has been adapted to reflect subtle differences in practice and law in these countries. We have partners in services in these three countries who will be conducting the trial there in accordance with this protocol and their own local ethics and clinical governance requirements.

NCT ID: NCT03320057 Recruiting - Pregnancy Related Clinical Trials

Medication Abortion Via Pharmacy Dispensing

Start date: June 1, 2018
Phase: Phase 4
Study type: Interventional

This mixed-methods study follows a prospective cohort of patients receiving Mifeprex ® (mifepristone) for medication abortion dispensed by pharmacists after undergoing standard clinical evaluation. Women participating in this study will obtain mifepristone and misoprostol from the pharmacy instead of in the clinic. To assess feasibility, acceptability, and effectiveness of pharmacy dispensing of mifepristone, the study will survey patients, evaluate their clinical outcomes from electronic health records, and survey and interview pharmacists at study sites.

NCT ID: NCT03047551 Completed - Abortion Early Clinical Trials

Transabdominal and Transvaginal Sonography in Medical Abortion

Start date: July 2016
Phase: N/A
Study type: Interventional

The investigator will perform a multicenter, randomized controlled trial in practices that routinely use transvaginal sonography (TVS) to compare how often clinicians order additional testing prior to medical abortion after the use of either TVS or transabdominal ultrasound (TAS) in medical abortion eligibility assessment. Women will be randomized to receive either TVS or TAS prior to medical abortion. We anticipate enrolling 800 patients receiving care from about 30 providers over 6-8 months. The primary study outcome will be the proportion of women that requires additional evaluation after sonography, prior to determination of medical abortion eligibility. The second primary outcome will be patient satisfaction, determined by a patient satisfaction questionnaire utilizing a visual analog scale.

NCT ID: NCT02522078 Completed - Abortion Early Clinical Trials

Dry vs Wet Misoprostol for Cervical Dilation in First Trimester Abortion

Start date: August 2015
Phase: Phase 4
Study type: Interventional

This study aims to verify whether the moisture of 400 µg of misoprostol pre uterine evacuation increases the dilatation of uterine cervix compared to dry misoprostol