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5-Fluorouracil Toxicity clinical trials

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NCT ID: NCT03486340 Recruiting - Clinical trials for Acute Coronary Syndrome

Prevention of Chest Pain in Chemo-treated Cancer Patients

CATCH
Start date: April 11, 2018
Phase: N/A
Study type: Interventional

This is a prospective, exploratory, randomised clinical trial. Patients with diagnosed cancer that are to be treated with 5-fluorouracil (5-FU) will be randomised into standard oncological treatment or a cardiological assessment prior to the 5-FU treatment. The investigators hypothesize that aggressive management of ischemic risk factors in asymptomatic patients will reduce the number of hospitalisations and investigations for acute coronary syndrome during and after 5-FU treatment and that patients with high coronary artery calcium scores are more likely to experience chest pain during the treatment with 5-FU.