Clinical Trials Logo
  1. Home
  2. Zika Virus
  3. NCT04064905

Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults

Zika Virus Clinical Trial

Official title:
A Phase 1, Randomized, Observer-Blind, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults

Clinical Trial Summary

This clinical study will evaluate the safety, tolerability and reactogenicity of mRNA-1893 Zika vaccines in flavivirus seronegative and flavivirus seropositive participants

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04064905
Study type Interventional
Source ModernaTX, Inc.
Contact
Status Completed
Phase Phase 1
Start date July 30, 2019
Completion date March 22, 2021
View Details
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT04182685 - Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua
Enrolling by invitation NCT04398901 - Neurodevelopmental Outcomes in ZIKV-Exposed Children
Completed NCT02996890 - Zika-Vaccine Dose Finding Study Regarding Safety, Immunogenicity and Tolerability (V186-001) Phase 1
Completed NCT03188731 - ZIKAlliance Pregnant Women Cohort
Completed NCT03110770 - VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents Phase 2
Active, not recruiting NCT04917861 - A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas Phase 2
Completed NCT02794181 - Zika Virus and Related Arbovirus Infections in Deferred Blood Donors (ZVADD)
Recruiting NCT01099852 - Cohort of Patients Infected by an Arbovirus
Completed NCT03611946 - Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults Phase 1
Completed NCT03106714 - Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil
Completed NCT02979938 - Understanding Excretion and Infectivity of Zika Virus in Semen During and After Infection
Recruiting NCT03227601 - Effect of a Posture Adapter for 12 to 24-month Children With Zyka Virus Syndrome N/A
Completed NCT03393286 - ZIKAlliance Children Cohort (ZIKAllianceCH)
Completed NCT03425149 - Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults Phase 1
Recruiting NCT05123222 - Evaluation of Two Zika Viruses for Use in Controlled Human Infection Models (CHIM) Phase 1
Completed NCT02733796 - Persistence of Zika Virus in Semen After Acute Infection
Completed NCT03014089 - Safety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects Phase 1
Completed NCT03263195 - Prospective Cohort Study of HIV and Zika in Infants and Pregnancy
Withdrawn NCT03204409 - ZIKAlliance Natural History Study