Clinical Trials Logo

Clinical Trial Summary

Double blinded, randomized, placebo-controlled, dose finding, multi-center, phase 1 trial in 48 healthy volunteer subjects. After completion of screening procedures, the subjects are randomized to one of four treatment groups (different dosage strengths and placebo) All subjects will receive study treatment at day 0 and will return on day 28. Subjects randomized to treatment groups with two vaccinations will receive a second treatment at day 28. Subjects will return on day 56 for the final visit.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02996890
Study type Interventional
Source Themis Bioscience GmbH
Contact
Status Completed
Phase Phase 1
Start date May 3, 2017
Completion date April 17, 2018

See also
  Status Clinical Trial Phase
Enrolling by invitation NCT04182685 - Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua
Enrolling by invitation NCT04398901 - Neurodevelopmental Outcomes in ZIKV-Exposed Children
Active, not recruiting NCT03188731 - ZIKAlliance Pregnant Women Cohort
Completed NCT03110770 - VRC 705: A Zika Virus DNA Vaccine in Healthy Adults and Adolescents Phase 2
Recruiting NCT04917861 - A Study of Zika Vaccine mRNA-1893 in Adult Participants Living in Endemic and Non-Endemic Flavivirus Areas Phase 2
Completed NCT02794181 - Zika Virus and Related Arbovirus Infections in Deferred Blood Donors (ZVADD)
Recruiting NCT01099852 - Cohort of Patients Infected by an Arbovirus
Recruiting NCT03611946 - Evaluation of the Safety and Immunogenicity of the Live Attenuated Zika Vaccine rZIKV/D4Δ30-713 in Flavivirus-naïve Adults Phase 1
Completed NCT04064905 - Safety, Tolerability, and Immunogenicity of Zika Vaccine mRNA-1893 in Healthy Flavivirus Seropositive and Seronegative Adults Phase 1
Completed NCT03106714 - Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil
Completed NCT02979938 - Understanding Excretion and Infectivity of Zika Virus in Semen During and After Infection
Recruiting NCT03227601 - Effect of a Posture Adapter for 12 to 24-month Children With Zyka Virus Syndrome N/A
Recruiting NCT03393286 - ZIKAlliance Children Cohort (ZIKAllianceCH)
Completed NCT03425149 - Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults Phase 1
Completed NCT02733796 - Persistence of Zika Virus in Semen After Acute Infection
Completed NCT03014089 - Safety, Tolerability, and Immunogenicity of mRNA-1325 in Healthy Adult Subjects Phase 1
Completed NCT03263195 - Prospective Cohort Study of HIV and Zika in Infants and Pregnancy
Suspended NCT03204409 - ZIKAlliance Natural History Study