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Clinical Trial Summary

In this study, The investigators aims to evaluate the efficacy and safety of topical hyaluronic acid nanoparticles as a novel nanodermatological tool in periocular rejuvenation as a replacement approach of invasive dermal filler injections.


Clinical Trial Description

Tear trough deformity is a main concern of many people (males or females) with age range of 21 to 65 years old or older. Such condition is characterized by a sunken appearance of the eye that results in an aged and dissipated appearance to the eye.Treatment modalities range from camouflage make up, laser resurfacing, platelet-rich plasma therapy, carboxy therapy, mesotherapy, volume augmentation with injectable hyaluronic acid fillers and fat, as well as surgical procedures such as blepharoplasty. Consequently, safe, effective and less invasive treatment options of the tear trough have remained a challenge. The study will include 30 adult patients (male or female) suffering tear trough deformity. They will be selected from Dermatology Outpatient Clinic of Alexandria Main University Hospital. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05742399
Study type Interventional
Source Alexandria University
Contact Shaimaa I Omar, MD
Phone +201001949540
Email shimoderma@yahoo.com
Status Recruiting
Phase N/A
Start date December 21, 2022
Completion date December 2023

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