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Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients

Wounds and Injuries Clinical Trial

Official title:
Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients

Clinical Trial Summary

The purpose of this study is to determine whether an intravenous salt solution called "Plasmalyte" causes less abnormality of the body's acid levels than a solution called "Normal Saline."

Clinical Trial Description

Electrolyte-containing intravenous fluids are routinely administered to patients in the first few hours after acute traumatic injury. Although Normal Saline (0.9% sodium chloride) is commonly used in this setting, it causes a hyperchloremic acidosis that may exacerbate metabolic derangements that occur after acute injury. Plasmalyte A is a solution that more closely matches physiologic electrolyte levels. In this study, we will evaluate whether Plasmalyte A results in less disturbance of the base deficit 24 hours following traumatic injury than does Normal Saline. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01270854
Study type Interventional
Source University of California, Davis
Contact
Status Completed
Phase N/A
Start date February 2011
Completion date April 2012
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