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Wound Infection clinical trials

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NCT ID: NCT02664168 Recruiting - Clinical trials for Surgical Wound Infection

A Comparative Study to Assess the Prevention of Surgical Site Infection (SSI's) in Revision Total Joint Arthroplasty Patients Treated With Single-Use Negative Pressure Wound Therapy (PICO™) or Standard Care Dressings (AQUACEL® Ag SURGICAL Dressing)

Start date: January 2016
Phase: N/A
Study type: Interventional

The aim of this study is to assess the prevention of incision healing complications in patients undergoing revision TKA and THA treated with either Single-Use NPWT (PICO) compared to standard of care dressings (AQUACEL Ag Surgical Dressing). All patients undergoing a revision TKA and THA who consent to taking part in the study, and meet the eligibility criteria will be included onto the study. Patients will be followed up for a period of up to 3 months to determine if there are any latent incision healing complications

NCT ID: NCT02331485 Recruiting - Wound Infection Clinical Trials

Randomised Control Study to Asses the Role of Negative Pressure Wound Therapy (NPWT) in the Management of Wound in Surgical Patient

Start date: August 2014
Phase: N/A
Study type: Interventional

Aim of the study is to assess the role of negative pressure therapy in the prevention of the complication of the laparotomy wound in the high risk patients group. Primary outcome: Reduction in wound infection rate by 50% Secondary outcome: Reduction of the length of hospital stay Decrease of using abx. for wound management Decrease cost of patient treatment

NCT ID: NCT02143336 Recruiting - Colorectal Surgery Clinical Trials

Subcuticular Continuous Suture Versus Skin Staples to Reduce Surgical Site Infections in Colorectal Surgery Patients

Start date: September 2013
Phase: N/A
Study type: Interventional

A comparison of skin closure techniques (standard skin closure with staples versus a continuous (subcuticular) absorbable suture), to determine if this changes the rate of post operative wound infections in elective colorectal surgery patients.

NCT ID: NCT02143089 Recruiting - Wound Infection Clinical Trials

Catheterization During Second Elective Caesarean Delivery

CDSECD
Start date: August 2013
Phase: N/A
Study type: Interventional

Use versus non use of urinary catheterization during Second Elective caesarean delivery:

NCT ID: NCT02116010 Recruiting - Wound Infection Clinical Trials

Evaluation of Phage Therapy for the Treatment of Escherichia Coli and Pseudomonas Aeruginosa Wound Infections in Burned Patients

PHAGOBURN
Start date: July 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The objective of PHAGOBURN is to assess tolerance and efficacy of local bacteriophage treatment of E. coli or P. aeruginosa wound infections in burned patients.

NCT ID: NCT02084017 Recruiting - Clinical trials for Peripheral Vascular Diseases

Negative Pressure Wound Therapy for the Prevention of Surgical Site Infection Following Lower Limb Revascularization

Start date: July 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the current standard of wound care following vascular operations compared to to a negative pressure wound therapy (vacuum dressing) and the rate of surgical site infections (SSIs) in patients undergoing surgery to restore blood flow to the lower limb(s). Negative pressure wound therapy consists of a closed, sealed system that produces negative pressure (vacuum) to the wound surface. The device itself consists of open-cell foam that is sealed with an occlusive adhesive dressing (covers and sticks to the incision) and suction is maintained by connecting suction tubes to a vacuum pump and waste collector. The investigators objectives are to determine whether there will be any reduction in surgical site infection and this potential reduction will influence length of hospital stay, emergency room visits, antibiotic use and need for re-operation.

NCT ID: NCT01954719 Recruiting - Clinical trials for Complications; Cesarean Section

Is Routine Cervical Dilatation Necessary During Elective Caesarean Section? A Randomised Controlled Trial

Start date: November 2012
Phase: N/A
Study type: Interventional

The purpose of this prospective randomised study was to determine the effect of routine cervical dilatation during elective caesarean section on maternal morbidity

NCT ID: NCT01907542 Recruiting - Wound Infection Clinical Trials

A Trial Comparing Stapled Versus Monocryl Sutured Skin Closure for Elective Open Colectomy

Start date: June 2013
Phase: N/A
Study type: Interventional

Background Stapled skin closure is frequently performed following open colectomies. However, its pain and cosmetic outcomes have been suboptimal. Monocryl sutured skin closure has been shown to be cosmetically superior and does not require removal of the sutures. But its association with wound infection has been questioned Aims This study aims to compare the outcomes using skin stapler or Monocryl suture in the skin closure following open colectomy. Hypotheses We believe Monocryl suture is associated with reduced pain and better cosmesis. Methodology Inclusion criteria: All patients who underwent elective open colectomy for various etiologies Exclusion criteria: i) Emergency laparotomies ii) Patient who require the creation of a stoma After consenting for the trial, patients will be randomized into either the skin stapler or the Monocryl suture group. Randomization is performed using a computer model. To minimize confounders, the pre-operative preparation and antibiotics regime will be standardized. The closure of the fascia and the skin will also be performed by at least a Registrar. The wounds will then be covered with a thick sterile dressing to blind the patient and the research assistant. The wound will only be reviewed on the POD 3. The patient is scheduled to return on POD 14, POD 30, 3 and 6 months post operatively upon discharge. Some of the variables that will be collected for this study include: 1. Time taken for skin closure 2. Superficial surgical site infection 3. Pain score 4. Cosmesis We aim to enrol 72 participants in each group. Importance/Impact to Medicine This study will validate the role of Monocryl suture as an effective method for skin closure following open colectomy. We believe Monocryl sutured closure can potentially change the practice of surgeons worldwide for the benefits of the patients.

NCT ID: NCT01769144 Recruiting - Pain Clinical Trials

Acticoat Absorbent and BCT Antimicrobial for STSG Donor Site on Thigh

Start date: January 2013
Phase: N/A
Study type: Interventional

This study aims to compare the effectiveness of two wound dressings, Acticoat Absorbent (AA) and BCT Antimicrobial (BCT) on Split Thickness Skin Graft (STSG) donor site.

NCT ID: NCT01716273 Recruiting - Infected Wounds Clinical Trials

Use of White Granulated Sugar on Wounds

Start date: June 2011
Phase: N/A
Study type: Interventional

How effective is sugar in reducing the debriding of sloughy, necrotic or infected exudating wounds compared with standard treatment?