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Wound Healing clinical trials

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NCT ID: NCT06459947 Recruiting - Pain Clinical Trials

Effect of Cyanoacrylate and Concentrated Growth Factor on Palatal Donor Site

Start date: March 2, 2024
Phase: N/A
Study type: Interventional

The aim of this planned randomized controlled clinical study is to evaluate the morbidity of the palatal donor area after free gingival graft (FGG) operations. In this study, wound healing and pain levels in the palatal region will be evaluated after cyanoacrylate and concentrated growth factor (CGF) applications.

NCT ID: NCT06109844 Not yet recruiting - Venous Leg Ulcer Clinical Trials

FORCEREPAIR - A Wound Exudate Investigation

Start date: January 30, 2024
Phase:
Study type: Observational

The observational longitudinal study will collect wound exudate from twenty patients with venous leg ulcers. Wound exudate samples are collected using twenty-four-hour collection with polyurethane foam, bandages and the NovaSwab method. Each patient is seen four times where wound exudate and the bacteria microbiome are sampled and wound size is monitored with advanced planimetric tools.

NCT ID: NCT06035523 Recruiting - Diabetic Foot Clinical Trials

Clinical Study Evaluating Wound Closure With Endoform™ and Symphony™

Start date: December 29, 2021
Phase: N/A
Study type: Interventional

Study will evaluate the performance and safety of Endoform™ Natural and Endoform™ Antimicrobial in conjunction with Symphony™ in the treatment of chronic non-healing diabetic foot ulcers after 12 weeks of treatment.

NCT ID: NCT05991921 Completed - Wound Healing Clinical Trials

The Effect of TENS Applied in the Early Postpartum Period on Incision Healing, Pain and Comfort

Start date: January 26, 2023
Phase: N/A
Study type: Interventional

Objective: In this study, it was aimed to determine the effect of TENS applied in the early postpartum period after cesarean section on incision healing, pain and comfort. Methods: This study was designed as randomized, single-blind, placebo-controlled. All participants signed an informed consent statement before starting the study. The study sample of 138 (TENS group n=46, placebo group n=46, control group n=46). TENS application, postpartum 10-12. at hours and 14-16. It was applied twice for 30 minutes each. Researcher 1 programmed the TENS unit and was the only researcher who knew whether TENS was active or in placebo mode. The pretest data were applied to the participants who met the inclusion criteria and volunteered to participate in the study, in the patient rooms 10 hours after the cesarean section. Post-test data were obtained by the same investigator 16 hours after cesarean section. Data were obtained with Personal Information Form, Postoperative Recovery Index (PoRI), REEDA Scale, Visual Analogue Scale (VAS), and Postpartum Comfort Scale (PPCQ).

NCT ID: NCT05942235 Enrolling by invitation - Clinical trials for Educational Problems

The Use of Microlearning in Nursing Education

Start date: October 6, 2022
Phase:
Study type: Observational

The goal of this randomized controlled study is to evaluation the effect of mobile application-based wound healing course on clinical reasoning skills in nursing student. The main questions it aims to answer are: - Does microlearning-based courses have an effect on clinical reasoning skills of nursing students compared to traditional courses? - Does microlearning-based courses have an effect on the retention of knowledge in nursing students compared to traditional courses? Participants will consist of students enrolled in the Surgical Diseases Nursing course in the fall and springs semester of the 2022-2023 academic year in the Department of Nursing at the Faculty of Health Sciences of Karadeniz Technical University. If there is a comparison group: Researchers will compare experimental group to see if control group.

NCT ID: NCT05902793 Recruiting - Wound Healing Clinical Trials

Evaluating the Efficacy and Safety of the VERAFLO™ Dressing Kit for Wound Bed Preparation in Open Wounds

Start date: August 11, 2020
Phase: N/A
Study type: Interventional

The objectives are to evaluate the efficacy and safety of the V.A.C. VERAFLO™ Dressing Kit for wound bed preparation in open wounds with extensive soft tissue damage in this trial.

NCT ID: NCT05846152 Not yet recruiting - Wound Healing Clinical Trials

Study of the Concordance of the Measurements Between the Evaluation of the Area of a Wound by the Technique of Transparent (Gold Standard) Compared to the Evaluation of the Area by the Algorithm of a Decision Support System (Wound-size)

PIXAIRE_I
Start date: April 30, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare the evaluation of a wound area and wound tissue content made by different methods on patient population with need for directed wound healing. The main question test of the concordance of the measurements between the evaluation of the area of a wound by the technique of transparent (Gold standard) compared to the evaluation of the area by the algorithm of a decision support system (WoundSize) Patient wounds will be examined: - by eye by the principal investigator - using a ruler by the principal investigator - by WoundCare algorithms (AKA WoundTrack) using smartphone photography by the principal investigator - tracing the outline of the wound using a transparent sheet by the principal investigator - by eye by a second investigator - using a ruler by a second investigator - by WoundCare (AKA WoundTrack) algorithms using smartphone photography by a second investigator. - tracing the outline of the wound using a transparent sheet by the second investigator

NCT ID: NCT05614557 Completed - Wound Healing Clinical Trials

Impact of Silicon-based Formulations on Wound Healing of Laser-induced Microscopic Skin Lesions

SPASM11
Start date: March 21, 2023
Phase: N/A
Study type: Interventional

Delayed wound healing is considered a health problem with devastating consequences for patients, healthcare systems, and societies. Over the past 20 years, many other groups, as well as ourselves, have evaluated various alternatives to improve wound healing. Despite this, the scientific evidence demonstrating the efficacy of recently developed treatments is often limited. Stratacel® and Stratamed® are two gels approved by Swissmedic and the FDA for use in improving wound healing. To this end, the efficacy of these formulations has been visually tested by a physician or by patients. Using the most advanced medical technologies (confocal microscopy and LCOCT), this study aims to investigate the effect of these formulations on the healing of human skin. For this research, a total of 20 volunteers will be included in this study. Volunteers will have up to 7 follow-up appointments over 21 days. Each appointment will last approximately 30 minutes and will be used to perform external measurements of skin healing. All volunteers will use the same formulations (Stratacel® and Stratamed®) with the only difference between volunteers being the anatomical area of application of the formulation. This will be determined by chance. The active participation of the participant is requested for the application of the formulations on the skin twice a day during the trial.

NCT ID: NCT05506215 Terminated - Diabetic Foot Clinical Trials

Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers

DFUs
Start date: July 10, 2022
Phase: N/A
Study type: Interventional

The study will evaluate the efficacy of SynPath™, a synthetic dermal matrix, in the treatment of diabetic foot ulcers in subjects with diabetes mellitus versus Standard of Care treatment. Half the subjects with be treated using SynPath™ while the other half will receive Standard of Care treatment

NCT ID: NCT05501327 Recruiting - Wound Healing Clinical Trials

Dose Regimen Study of SLI-F06 in Healthy Volunteers

Start date: July 25, 2022
Phase: Phase 2
Study type: Interventional

Multi-center, dose-regimen, double-blind study evaluating the safety and efficacy of 4 doses of SLI-F06 compared with vehicle for improvement in scar appearance