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Wound Heal clinical trials

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NCT ID: NCT04901325 Recruiting - Wound Heal Clinical Trials

Baricitinib in the Treatment of Adults With Pyoderma Gangrenosum (PG)

Start date: October 2023
Phase: Phase 2
Study type: Interventional

An Open-Label, Proof-Of-Concept, Study of Baricitinib for the Treatment of Pyoderma Gangrenosum

NCT ID: NCT04898816 Completed - Wound Heal Clinical Trials

Comparing the Effectiveness of Cyanoacrylate Tissue Adhesives and Conventional Sutures

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

This study compares the effectiveness of two materials used for intraoral wound closure after removal of impacted mandibular third molar tooth. One Group received braided black silk suture and the other group received N-butyl 2-octyl cyanoacrylate tissue adhesives.

NCT ID: NCT04886882 Enrolling by invitation - Wound Heal Clinical Trials

Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model

Start date: March 22, 2021
Phase: Early Phase 1
Study type: Interventional

An experimental study examining wound healing in 5 different groups on 30 rats.

NCT ID: NCT04865952 Completed - Wound Heal Clinical Trials

Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

NCT ID: NCT04849143 Recruiting - Diabetes Clinical Trials

The Effectiveness of Stingless Bee Honey (Kelulut Honey) Versus Gel in Diabetic Wound Bed Preparation

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

There has been no study yet on the effect of stingless bee honey (Kelulut honey) produced by Melipolini sp. in diabetic wound healing in Malaysia. Kelulut honey, apart from possessing similar pro-healing properties with other honey, is also found to have a better antioxidant capacity, anti-inflammatory, and free radical scavenging activity than Tualang honey. These effects are due to the much higher content of phenolic and flavonoid substances in Kelulut honey, the key bioactive factors promoting wound healing and preventing oxidative stress-related injury. Australian researchers have also recently discovered a novel source of the rare disaccharide trehalose in stingless bee's honey, which is highly anti-diabetic and antioxidating. This study aims to investigate the efficacy of honey against gel dressing for wound bed preparation among diabetic patients.

NCT ID: NCT04834817 Completed - Wound Heal Clinical Trials

Effect of Combined Red and Near Infrared Light-emitting Diode (LED) Therapy on Tissue Regeneration Post Laser Treatment

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of light therapy on wound healing after laser treatment.

NCT ID: NCT04829331 Terminated - Wound Heal Clinical Trials

Utility of Restrata With Split Thickness Skin Graft to Reconstruct the Forearm Donor Site

Start date: April 9, 2021
Phase: N/A
Study type: Interventional

Understand association between use of Restrata (Acera Surgical Inc., St. Louis, MO) in forearm flap reconstruction with donor site healing and function

NCT ID: NCT04805463 Completed - Wound Heal Clinical Trials

Different Platelet Concentrates After Gingivectomy and Gingivoplasty Evaluation of Its Effect on Early Wound Healing.

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effect of PRF, CGF and AFG application on early wound healing after gingivectomy and gingivoplasty operations. In the study designed split mouth, gingivectomy and gingivoplasty surgery were performed on 19 patients. The postoperative PRF, CGF, and AFG applied areas were compared with the control regions. 0th,7 th,14 th and 28 th on the days, the surgical area was painted with mira-2-tone solution and evaluated in the ImageJ program. Measurements of clinical periodontal parameters including PI, GI, SC and SD were recorded at the beginning, after IPT and 28 days after the operation. Wound healing was evaluated with H2O2 test, VAS-Pain, and LTH index on 7th, 14th and 28th days. The patients were asked to evaluate their aesthetic perceptions on the VAS aesthetic scale.

NCT ID: NCT04794621 Completed - Wound Heal Clinical Trials

Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection

EDT BioFilm
Start date: June 3, 2021
Phase: N/A
Study type: Interventional

There are currently limited treatments available that show anti-biofilm efficacy for wound infection management Biofilms account for over 80% of infections and approximately 65% of nosocomial infections caused by microorganisms in the developed world involve biofilms. There clearly is a need for cost effective, highly stable, easily obtained biofilm targeted strategies for treatment of chronic wound biofilm infections. The information generated from this project has the potential of providing considerable benefits to wound care by determining the efficacy of EDT dressing in managing wound biofilm infection and efficacy in wound healing and closure. Such knowledge could help therapeutic strategies and could provide information for future clinical studies to further understanding -of EDT wound dressings.

NCT ID: NCT04743375 Recruiting - Wound Heal Clinical Trials

Clinical Efficacy of Silk Sericin Dressing With Collagen for Split-thickness Skin Graft Donor Site Treatment

Start date: February 2021
Phase: N/A
Study type: Interventional

To examine the efficacy and safety of sericin dressing with collagen in STSG donor site treatment comparing with Bactigras®. Around 30 patients will be enrolled in this study.