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Wound Heal clinical trials

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NCT ID: NCT05357287 Recruiting - Wound Heal Clinical Trials

Closed Incisional Negative Pressure Wound Therapy in Post-surgical Wound Care of Patients With Periprosthetic Joint Infection

Start date: March 15, 2022
Phase: N/A
Study type: Interventional

In the proposed study, we will apply Prevena on the surgical wound right after closure of the wound in the operating theater. Prevena will be used for 7 days, unless there is ongoing infection or much wound drainage that requires debridement. Most periprosthetic joint infections are from hematogenous origin. Hence, it is considered clean wound unless there is a discharging sinus.

NCT ID: NCT05282615 Completed - Wound Heal Clinical Trials

Impact of Daily Use of The Emanate Tray Adjunct to Full Mouth Debridement Compared to Full Mouth Debridement Alone

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

The study is a 56-day (8-week), randomized, controlled, examiner-blinded, parallel-design study of patients with existing Stage II or Stage III periodontitis. After eligibility determination, subjects will be randomized to the following groups: - Group 1: Full mouth periodontal debridement + Emanate Tray (treatment group) - Group 2: Full mouth periodontal debridement alone (control group) Patients will be evaluated at Baseline and on Days 14, 28, and 56 for primary endpoint and at baseline and on day 56 post-treatment for secondary (efficacy) endpoints.

NCT ID: NCT05270382 Completed - Wound Heal Clinical Trials

Effect of Mouthwashes on Oral Wound Healing and Microbiome

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this clinical research study is to investigate if mouthwashes to be tested can affect oral mucosal wound healing and change the oral microbiome (bacteria colonization) or expression of selected biomarkers.

NCT ID: NCT05252260 Completed - Wound Heal Clinical Trials

Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional technique

NCT ID: NCT05234086 Recruiting - Wound Heal Clinical Trials

Cell Therapy for Diabetic Foot Ulcer

Start date: January 2, 2020
Phase: Phase 2
Study type: Interventional

Diabetes is a highly prevalent chronic disease that affects a large part of the world's population. Among the most costly complications is the diabetic foot ulcer, where its decompensation can result in limb amputation, a risk 10 to 20 times more frequent for diabetic population. Two underlying pathophysiological mechanisms are mainly identified: neuropathy and problems associated with vasculature and blood supply, in addition to the incidence of infections, which further impairs prognosis. Skin regeneration involves several overlapping and consecutive stages, which in the case of a diabetic patient are altered. Although healing protocols have been significantly improved at the country level, and there is also a large amount of medical supplies for treatment of these wounds, there are still patients with ulcers refractory to this care that end in amputation. In response to this, new treatments have emerged that use biomaterials and cells of the patient himself, which attempt to emulate the architecture and functionality of normal tissue. Cell therapy has gained strength in recent years, with more and more studies indicating the positive effect of cell application on healing of chronic wounds with underlying pathologies, such as diabetes. The product to be evaluated corresponds to a combined medical device, which conveys a cellular therapy, known as InbioDerm+C. The purpose of this Phase II clinical study is to determine whether InbioDerm+C treatment plus advanced healing is equal to or superior to advanced healing in a diabetic population with Wagner II grade foot ulcer treated in Villa Alemana primary care family centers, Las Américas, Juan Bautista Bravo Vega and Eduardo Frei.

NCT ID: NCT05186532 Completed - Pain, Postoperative Clinical Trials

Dry Heat Versus Sitz Bath On Episiotomy Wound Heating And Pelvic Pain

Dry_Heat
Start date: January 5, 2021
Phase: N/A
Study type: Interventional

Objective: To compare the effect of dry heat versus moist heat application on episiotomy wound healing and pain among postnatal mothers. Research hypothesis H0: Postnatal mothers who apply dry heat on their episiotomy wound experience the same wound healing and pain as those who apply moist heat. H1: Postnatal mothers who apply dry heat on their episiotomy wound experience faster wound healing and less pain than those who apply moist heat. H2: Postnatal mothers who apply moist heat on their episiotomy wound experience faster wound healing and less pain than those who apply dry heat.

NCT ID: NCT05169814 Recruiting - Wound Heal Clinical Trials

Micro/Nanobubbles (MNBs) for Treatment of Acute and Chronic Wounds

MNB
Start date: October 9, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of Micro/nanobubbles (MNB's) for the healing of acute and chronic wounds.

NCT ID: NCT05161403 Not yet recruiting - Wound Heal Clinical Trials

The Efficacy of Hyaluronic Acid and Honey in Healing of Multiple Extraction Sockets of Primary Teeth Compared to Saline

Start date: February 22, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of hyaluronic acid and honey compared to saline in healing of multiple extraction sockets of primary teeth in a group of children aging from Two to Seven years old.

NCT ID: NCT05133570 Recruiting - Wound Heal Clinical Trials

Study Evaluating the Effectiveness of Treatment With Vista Care®, in Arterial Ulcers of the Lower Extremities

VISTA CARE
Start date: October 29, 2021
Phase:
Study type: Observational

The prevalence of chronic wounds is around 2 million people in France per year. A chronic wound is a wound that has been evolving for more than 6 weeks. The main causes are: venous causes, arterial causes and microcirculatory causes. In some aetiologies (particularly arterial causes), there is no radical therapeutic solution (no possibility of revascularisation) and the wounds are often difficult to treat and may even eventually lead to amputation. The recommendations for treating wounds are (in addition to carrying out an etiological treatment when possible) to carry out mechanical detersion and to maintain a moist wound environment. In addition to various medical devices such as dressings, adjuvant treatments that are not specific to the etiology of the wound, such as electrotherapy, negative pressure therapy or other devices such as the VistaCare®, are indicated in France.

NCT ID: NCT05122130 Recruiting - Wound Heal Clinical Trials

Effect of Melatonin on Palatal Wound Healing (Randomized Controlled Clinical Trial)

Start date: November 20, 2021
Phase: Phase 2
Study type: Interventional

The aim of the study is to assess the effect of topical melatonin loaded gelatin sponge on donor palatal site healing, after palatal graft harvesting.